KEGG   Maylandia zebra (zebra mbuna): 101473981Help
Entry
101473981         CDS       T02814                                 

Definition
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
mze  Maylandia zebra (zebra mbuna)
Pathway
mze00562  Inositol phosphate metabolism
mze04012  ErbB signaling pathway
mze04068  FoxO signaling pathway
mze04070  Phosphatidylinositol signaling system
mze04140  Autophagy - animal
mze04150  mTOR signaling pathway
mze04210  Apoptosis
mze04218  Cellular senescence
mze04370  VEGF signaling pathway
mze04510  Focal adhesion
mze04620  Toll-like receptor signaling pathway
mze04625  C-type lectin receptor signaling pathway
mze04810  Regulation of actin cytoskeleton
mze04910  Insulin signaling pathway
mze04914  Progesterone-mediated oocyte maturation
mze04933  AGE-RAGE signaling pathway in diabetic complications
Module
mze_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:mze00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101473981
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    101473981
   04370 VEGF signaling pathway
    101473981
   04068 FoxO signaling pathway
    101473981
   04070 Phosphatidylinositol signaling system
    101473981
   04150 mTOR signaling pathway
    101473981
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    101473981
  Cell growth and death
   04210 Apoptosis
    101473981
   04218 Cellular senescence
    101473981
  Cellular community - eukaryotes
   04510 Focal adhesion
    101473981
  Cell motility
   04810 Regulation of actin cytoskeleton
    101473981
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    101473981
   04625 C-type lectin receptor signaling pathway
    101473981
  Endocrine system
   04910 Insulin signaling pathway
    101473981
   04914 Progesterone-mediated oocyte maturation
    101473981
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    101473981
Enzymes [BR:mze01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     101473981
Membrane trafficking [BR:mze04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    101473981
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_p85B PI3K_C2 DUF2321 DUF4135 C2
Motif
Other DBs
NCBI-GeneID: 101473981
NCBI-ProteinID: XP_004570542
Position
LG18
AA seq 1068 aa AA seqDB search
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt NT seq  +upstreamnt  +downstreamnt
atggctcccagaccatcatcgggagaactatgggggatgcacttgatgccccccagcatt
ctagtggactgccttctgccaaatggcatgattctcacgttggagtgcctccgggaggcc
acacttactacagtcaagcatgagcttttcaaagaggccaggaagtaccctctctaccat
ctgctgcaggaggagagctcctacatctttgttagtgtcacccaggaagcagagcgggag
gagttttatgatgagaccaggaggttatgtgatcttaggcttttccaggccttcctcaag
gttattgagccagtaggcaacagagaagagaagattctcaacagagagataggttttgct
attggtatgcctatatgtgagtttgatttggtgaaagaccctgaggtgcaggacttcaga
aggaacattttaaacgtttgcaaagaagctgtggacctcagagacagcaacggaccccac
agcagagcattgtacgtctaccctcccaatgttgaatcctcagcagagcttcccaggcac
atctatagcaagctagacaaaggtcaaatcattgtggtcatttgggtcattgtttcgccc
accaatgacaaacagaagtacaccctgaagatcaatcatgattatgtaccagagcaagtg
attgcagaagccattcggaagaagacgcgcagcatgctgctctcccaggagcagttaaag
atgtgtgtgcaggagtatcagggaaagtacatcctcaaagtctgcggctgtgatgagtac
ttactggagaaataccctctgagtcagtacaagtatgtgcgcagctgtatcatgctggga
agaatgcctaacctgatgctaatgtcaaaagacagcctgtattcccaactgcccatggat
ttcttcaccatgccgtcatatgcaaggcgaatatccacagcaacaccctacatgaatggg
gaaacagccaccaagaatctgtggactatcaacggaacgctaaggattaagatactgtgc
gccacttatgtcaatgtcaacatcagagacattgacaagatctatgtcaggactgggata
taccatggtggagagcagctgtgcgacaatgtcaacacgctacgtgtgccgtgctcaaac
cccaggtggaacgagtggctgacttacgacatgtacattccagaagttccccgagctgcc
cgactctgcctctccatttgctctgtcaaaggacggaagggagctaaagaggaacactgt
cccctcgcctggggcaacattaacctgtttgactacacccacacactagtagcagggaag
atggctctcaacctgtggcctgtcccacatggcctggaagacctgctcaaccctatcggt
gtcacgggctccaaccctaacaaggaaaccccatgtctggagctggagtttgaccattac
agctcccctgtcaagtttcctgatatgtctaccattgaggatcatgcaaactggaacata
tccagagagcttggctttaattactgccacactggtttgagtaacagactggcacgggac
aaccccctgactgacggcgacaatgagcagctacggcaagtgtgtaacagagacccgctt
tctgaaatcactgagcaggagaaggacttcctgtggagacacagacatgactgcatcaat
atgccagagatccttcccaagatcctcctggctgtgaagtggaactccagagatgaggtt
gcacagatgtattgccttctaaaggactggcctgctatcaaaccagaacaagccatggag
ttgttggattgcaacttccccgatcctatggtcagagagtttgctgtgaagtgccttgag
aaatacctaactgatgacaaactctcccagtatctcattcagctggttcaggttctgaag
tacgagcagtaccttgataacccactcgcacggttcctgctgaaaaaggcgttaaccaat
cagaggataggacatttcttcttctggcatttaaagtcagagatgcacaacaagacagtg
agccagcggtttggtctgcttctggagtcctactgccgggcctgtggcatgtatctgaag
cacttgagcagacaggtggaggccatggagaagctcatcaatctcactgacctcctcaaa
caggagaaaaaagatgaggctcagaaggttcaaatgaagtttctggtggagcagatgaaa
agacctgactacatggatgcactgcaaagcttcacctctccgctgaatccggcacatcag
ctgggaaacctccgcctggaggaatgcaggatgatgtcgtcagcaaagagacctctgtgg
cttaactgggaaaacccagatatgatgtcggagctgctctttcagaacaatgaaatcatc
ttcaaaaatggagatgatctgaggcaggacatgctgacgctacagatcattaggataatg
gagaacatctggcagaaccaaggccttgatctcaggatgctgccctatggctgtttgtct
atcggcgactgcgtgggtttgatcgaggtggtgaggaactctcacaccatcatgcagatc
cagtgcaaaggaggcctaaagggggcgctgcagttcaacagccacactctacatcagtgg
ctcaaggataagaacaagggagagatgtacgaccaggccatcgatctgttcacacggtcg
tgcgcaggctactgtgtagctacatttatcctgggcataggagataggcacaacagcaac
atcatggttaaagatgatgggcagctgttccacatagattttggtcacttccttgaccac
aaaaagaagaagtttgggtacaagagggagcgcgtcccctttgtgctcacacaggacttt
ttgattgttattagcaaaggaacgcaagagtgcaccaaaacgagggagtttgaaagattc
caggagatgtgctacaaagcgtacctggcaatccggcagcacgccaacctcttcatcaac
ctcttctccatgatgctgggctcgggaatgcctgagctgcagtcgttcgacgacatcgct
tacatcaggaagaccctggccctggacaagtcggagcaggaggccctggactacttcatg
aagcagatgaacgacgctcaccacggcggctggactaccaagatggactggatcttccac
acgattcgccagcatgccatgaactga

DBGET integrated database retrieval system