KEGG   Maylandia zebra (zebra mbuna): 101474135
Entry
101474135         CDS       T02814                                 
Symbol
plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mze  Maylandia zebra (zebra mbuna)
Pathway
mze00562  Inositol phosphate metabolism
mze01100  Metabolic pathways
mze04020  Calcium signaling pathway
mze04070  Phosphatidylinositol signaling system
mze04261  Adrenergic signaling in cardiomyocytes
mze04270  Vascular smooth muscle contraction
mze04310  Wnt signaling pathway
mze04371  Apelin signaling pathway
mze04540  Gap junction
mze04621  NOD-like receptor signaling pathway
mze04912  GnRH signaling pathway
mze04916  Melanogenesis
Module
mze_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mze00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101474135 (plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101474135 (plcb3)
   04371 Apelin signaling pathway
    101474135 (plcb3)
   04020 Calcium signaling pathway
    101474135 (plcb3)
   04070 Phosphatidylinositol signaling system
    101474135 (plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101474135 (plcb3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    101474135 (plcb3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101474135 (plcb3)
   04916 Melanogenesis
    101474135 (plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101474135 (plcb3)
   04270 Vascular smooth muscle contraction
    101474135 (plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mze04131]
    101474135 (plcb3)
Enzymes [BR:mze01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     101474135 (plcb3)
Membrane trafficking [BR:mze04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    101474135 (plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    101474135 (plcb3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PH_14 DUF1154 EF-hand_like
Other DBs
NCBI-GeneID: 101474135
NCBI-ProteinID: XP_014266589
UniProt: A0A3P9B1T5
Position
LG3:27978125..28034743
AA seq 1254 aa
MAGAKPGVHALQLKPVAVHEELKKGGKFVKWDEEPNSTQPTLINLKVDPEGFFLYWTIGA
GQDVEILDISYIRDTRTGKYAKQPKDAKVKEVLGLTKEVNGEGKLLTVVYGNDLVNVSFL
NFQAMQEDVAKIWTDELFALSTNILSQNVSRNIFLYKAYTKLKLQVNQEGKIPVKNVIKM
FSDKKRVETALEQCGLINNKSEGIKPDDITWDAFQKLLDNLCLRPEIQSIFEESGSKRKP
FISLDQLMDFINRRQRDSRLNEVLYPPLKRDQVRQIMEKYETNTSQLERDQISLQAFSRY
LGGEENTIVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGNSSVEMYRQVLLTGCR
CIELDCWKGRPQDEEPYITHGFTMTTEIPFKEVIEAIAESAFKTSPYPVILSFENHVDSA
KQQAKMAEYCRTIFGDALLIEPLEKYPLSEGQLLPSPQELMGKILIKNKKKHHHHRPSES
GSIRRKEPGEQSSPHNDCPLTEEGSQLLSNGEEKLAERMVKDSEPRKSIGGEGESEEEEE
DESVAELKKPNSDEGTASSEANATEEMSNLVNYIEPVKFKTFEWAAKRKRFFEMSSFVET
KGMDALKSFPIEFVEYNKNQLSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLPM
QLNMGVFEYNGLSGYLLKPEFMRRTDKHFDPFTENIVDGIVANTVKIKVISGQFLTDKKV
GVYVEVDIFGLPADTKRKYRTKTSNGNSLDPVWDDEMFVFNKVVLPTLASLRIAVFEENG
KFIGHRILPVSAIRPGYHYINLKNELNQPLMLPSLLVYTEAQDYIPNEHQEYAEALTNPI
KHISEKHKRETQLASLLEDNSEVRQPLTNQPKEGENKRELSPGFGIPSPSPTPHPPPKED
PPDVIKLPAPVQSQKEDLIGTVLTDVKVQSVEELQQNKHYEKLLKKQRKELKELRKKHLK
KVSNLSKDQKTQLQSDTQRKRSQIEKQLKRSFKKSESQELVQSELAALDDLEKQKNQLKE
IHMQQLLKLREELFAIEREKQKTHLQEAHQKLKEIASECQAAQVKKVKELCEKEKKELQK
ILDRKRLNSISEAKNREKDKAESELNEINRKHIQDSVSLIRGLEEAQTRRDDKLLQRHRD
VLQRIDEELPQLKSQLDRKLEEEYHRLPEEICQHLQLELQNKNLQKNALFSALSNHSSPS
TGSGPPSNCSTPSNSSTPSRSTLHRSRDNSTVSLADSTSSSTTPVLSDAEMSFN
NT seq 3765 nt   +upstreamnt  +downstreamnt
atggccggggccaagccgggagtccacgcgctgcagctgaaacccgtggccgtccacgaa
gagctgaagaagggcggcaaattcgtcaagtgggacgaggagcctaacagtacacagccg
acgctgataaacctgaaagttgatccggaaggattcttcctctactggaccataggtgct
ggccaggatgtcgagattttggacatcagttacatcagggacaccagaacgggaaagtat
gccaaacagccaaaggacgcaaaggtgaaagaagtgctgggccttactaaggaggtgaac
ggagaagggaagctgttaaccgtcgtctatggcaatgacctggtcaacgtttctttcctc
aacttccaggccatgcaagaggatgtagcgaagatttggacagatgagctgttcgctttg
tccacaaacatactttcccagaatgtatcgcggaacatctttctttacaaagcgtacacg
aagttaaagcttcaagtgaaccaggaagggaagattccagtgaagaatgtcatcaagatg
ttttctgataaaaagagagtggagacagctctggagcagtgtggcctcattaataacaag
tcagagggaataaagccagatgatatcacctgggatgccttccagaagcttctggacaac
ttatgtcttcgacctgagatccagagcatctttgaggaaagtggctccaagaggaagccg
ttcatctctttggaccagctaatggacttcatcaaccgcaggcagagagactccagacta
aacgaggtgctctaccccccactgaaaagagaccaagtccgacagatcatggagaaatac
gagaccaacaccagtcagctggagagagaccaaatcagtttgcaggcattcagtcggtat
ctggggggagaggaaaacaccatcgtacctccagagaggctggacatcatcgacgacatg
aaccaaccgctctctcactactttatcaactcgtcacacaacacgtacctcacagtgggc
cagctgaccgggaattcttcggtggagatgtataggcaggtgctgctcaccggttgtcgc
tgtattgagctggactgctggaagggccgaccacaagatgaagaaccctacatcacccac
gggttcaccatgaccactgagatcccctttaaggaagtgattgaagccatagcagagagt
gctttcaagacctcgccataccccgtcatcctgtcctttgaaaaccacgtggattcagca
aagcagcaggctaagatggcagagtactgcaggacaatctttggagatgcgctgctcatc
gagccattggagaaatatccactgagcgaaggtcagctgctgccttcgccgcaggaattg
atggggaagattcttatcaaaaacaagaagaaacatcaccatcaccgaccctctgagagt
ggcagcataaggcgcaaagagccaggggagcagtcttcgcctcacaacgactgccctctg
acagaagagggaagccaactcctgtccaatggagaggaaaagctggctgaaaggatggtg
aaagactccgagcctcggaagtccattggaggtgaaggagagagcgaggaggaggaggag
gacgagtcggtggcagagctgaaaaagccaaactccgacgagggtaccgccagcagcgag
gcgaacgccacggaggagatgtcaaatctcgtcaactacattgaacccgtcaaatttaag
acctttgaatgggcagctaagaggaagaggttctttgagatgtcatcgtttgttgaaacc
aaaggcatggatgccctgaagagcttccctatagagtttgttgagtacaataagaaccag
ctgagccgaatctatcctaaaggaacaagagtagacagctccaactacatgcctcagctt
ttctggaacgtcggatgccagatggtggcgctaaacttccagacacttgaccttcctatg
cagctgaacatgggtgtgtttgagtataatggcctgagcggttacctgttgaagccagag
ttcatgagaaggacagacaaacactttgaccctttcacagaaaacatagtagacggcata
gtcgctaacacggtcaaaattaaagtgatctcaggccagttcctgacagataagaaggtt
ggtgtgtatgtggaagtggacatttttggacttccagctgacacaaaaaggaagtacaga
accaaaacatctaatgggaactcgctggaccctgtgtgggatgatgaaatgtttgtcttt
aacaaggtggtcctccctacactggcctctctgagaatagctgtgtttgaggaaaacggc
aagttcattggacaccggattctccctgtttcggctattaggccgggctaccattacatc
aacctgaagaatgagctaaaccagccgcttatgctgccgtcacttctggtttatactgaa
gctcaggactacatccctaatgaacaccaggagtatgcagaagctctcaccaaccctatt
aagcatatcagtgagaagcacaagagagagacacagctagctagtctcttagaagacaac
agtgaggtgagacagcctctcaccaaccagcccaaagaaggagagaacaagagagaactc
agtccaggatttggaatcccctccccttccccaacaccccatccccccccaaaggaagat
cctcctgatgtcatcaagttacctgcaccagtacaatctcagaaggaggacctcataggt
actgtcctaacagatgtcaaggttcagtctgtagaggagctgcagcagaataaacattat
gaaaagctccttaaaaaacaaagaaaagaactcaaagagctgcgcaagaaacatctgaag
aaggtgtctaatctaagtaaggaccagaaaacccagcttcagtctgacacccaaaggaaa
cgcagccagattgagaaacaactcaaacgcagtttcaagaaaagtgagtcccaggaactg
gtgcagagcgagttggctgccttggatgatctggagaagcagaagaatcagctgaaagag
attcacatgcagcaactcctaaaactacgtgaagagctttttgcaatcgaaagagagaag
caaaaaacacacctgcaagaggcccaccagaagttgaaggagattgccagtgaatgccaa
gcagctcaggtgaaaaaggtcaaggaactatgcgagaaggagaagaaagaactccagaag
atcctggacaggaaacgactaaacagcatcagtgaagccaagaaccgtgaaaaagacaaa
gctgaatcggaactgaatgagatcaacaggaaacacattcaagattctgtctctctaatc
cgtgggctggaggaagcgcagaccaggagagacgacaagctgctgcagaggcatcgggac
gtcctacaacgcatagacgaggagcttccacagcttaagtctcagttggatcggaaactg
gaagaggagtatcaccgccttcccgaggagatctgccagcacctacagctcgagctgcaa
aacaaaaatctccaaaagaacgcgctgttctccgccttgtccaatcatagcagtcccagt
acaggctcaggcccgccctccaactgctccacgccctctaactcgtcaacgcccagtcgg
agcactttgcacaggagccgggacaatagcaccgtctctctggccgattccacttcgtcg
tccaccacgcccgtcttgtcagacgcagaaatgtcgttcaattaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (50)   
   KEGG ORTHOLOGY (1)   
   RefGene (46)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (6)   
   Pfam (6)   
All databases (94)   

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