KEGG   Necator americanus (New World hookworm): NECAME_04225
Entry
NECAME_04225      CDS       T04867                                 
Name
(RefSeq) cullin family protein
  KO
K10609  cullin 4
Organism
nai  Necator americanus (New World hookworm)
Pathway
nai03420  Nucleotide excision repair
nai04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:nai00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    NECAME_04225
  09124 Replication and repair
   03420 Nucleotide excision repair
    NECAME_04225
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:nai04121]
    NECAME_04225
   03400 DNA repair and recombination proteins [BR:nai03400]
    NECAME_04225
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nai04147]
    NECAME_04225
Ubiquitin system [BR:nai04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Cullin
     NECAME_04225
DNA repair and recombination proteins [BR:nai03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      NECAME_04225
    TCR (transcription coupled repair) factors
     Cul4-CSA complex
      NECAME_04225
Exosome [BR:nai04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   NECAME_04225
SSDB
Motif
Pfam: Cullin Cullin_Nedd8 HbrB
Other DBs
NCBI-GeneID: 25344257
NCBI-ProteinID: XP_013296060
UniProt: W2SWF9
Position
Unknown
AA seq 986 aa
MTMCQKGCLQILTTAGETPMAENRRRGERGVIQPSLQHLRNPEKEEEAGPSVCNFLPQER
RICVQRSNGVNTSSGGGGSTSNSEHCPCAIVLFNVLITHNIFWMQSTNNGDTGVEVKSNS
SSPGTVNPKKSTFVLQKGAQKRSLSVFSPIQTVPIQKRPKMSEISDEMLSDEDSAEMYQQ
EFGEGEPEYMFERLIEGPNEEQFAADKGRDETFENMVDARAMRQISRGLPTVKKLTIKNF
RSKFRSISFLAKICQIRPHCLFIEKNDDVADLMATGWVTLEASINAIQTKQHITTSLEQL
YKVVESLCENKMARTTYDKLLENVRKWIRSFREDLKQKSNAGGVEFMKAIENLWSDYCQQ
MILIRNVFLYLDRTFILENIDESPIWESSLVIFREEIVVHGCVLKKLVDGILECIAAERA
GDQVDRSLLRALLRMLRTLDLYKQSFEEEFLTSTSVHYTHESMSLVRALETVEFLLYIER
RLREENERVDLYLDESTRTPLLMRAEKCMISDHMQDIVDNGLASLLNDNRVKDVTRLYSL
LSRVEGGVALLKTGFSTYIKKVGKAMIMDTQRDQTMVEDLMAFKDKLDVFVETCFGSEDE
KMKFAQAEKDAFDYFINTRGNKPAELIAKYMDARLRSANKEASDEQLDQLMNKVITLFRF
IQGKDVFEVFYKKDLAKRLLLGRSASVDAEKIMLSKLRQECGAGFTQKLEGMFRDMELSK
DLGVAFRNCQCSHDGTMASVRKCTGEGKFSLDTILYKIELGLTMMTVTLPKQLNACLQLY
ERFYDSRHTGRKLQWQPRLGQCVLKANFRTGCDKELKVSLFQAIVLLLFNNQSSWTATDI
MMATKLEQKEFVRTMVSLSCAKVRVLAKTPMNKEIKDDDVFTVNTDMKEMRFRIRISEVQ
MKETEEEYKAVEEEVNQDRQYQIDAAIVRVMKTRKKLNHQLLISELFAQLRFPVRAADLK
KRIGSLMERDYLRRCDEDPNAYQYVA
NT seq 2961 nt   +upstreamnt  +downstreamnt
atgacaatgtgtcagaaaggctgcctgcagattctcaccaccgctggtgagacacccatg
gctgagaatcgtcgtcgaggcgaaaggggagtaatacaaccttcactacaacatctacgt
aatccagaaaaggaagaagaggcaggtccctctgtttgcaacttcttgccccaagagaga
cgtatttgcgtacagcgatcaaatggcgtaaatacttcttcggggggggggggttcgaca
tcaaattcagaacactgtccttgcgctattgttttgttcaatgtgctgatcacacataat
atattttggatgcaatcaacaaataacggcgacaccggtgttgaagtgaagtcgaattca
tcgtcacctggaaccgtcaatccgaaaaagtccacttttgttttgcagaaaggcgcacag
aagcgatcactttctgttttttctccaatacaaactgtaccaatacaaaaacgacctaag
atgtcagaaattagcgatgaaatgttgagtgatgaggactctgcggagatgtatcaacaa
gagttcggtgaaggtgagcctgagtacatgttcgaacgactcattgaaggacctaatgaa
gaacaatttgctgcagacaagggacgcgacgaaacgttcgagaatatggtagatgcaaga
gcaatgagacaaatttcgcgaggtttgcctactgtaaagaaactgactatcaaaaacttt
cgcagtaagttcagaagtatatcctttcttgcaaaaatctgtcagattagaccgcattgt
ttgttcatagagaaaaatgacgatgttgccgacttgatggcaacgggttgggttacacta
gaggctagtataaatgcaatacaaacgaaacaacatattactactagtcttgagcaattg
tacaaggttgtggagtcattgtgtgaaaacaaaatggcaagaaccacttatgacaagttg
cttgaaaatgtgcgaaaatggattcggagcttcagagaggatttaaaacaaaaaagcaac
gcaggaggtgtcgagtttatgaaagcaatagagaacctttggagcgattactgtcagcaa
atgattcttataaggaatgtcttcttgtatcttgatagaacgttcattctggagaatatt
gatgaatctccgatatgggagtcgtctttggttatcttccgggaagagattgtggtgcac
ggctgcgtcctgaaaaaattggttgatggaattttagaatgtattgctgctgaaagggct
ggagatcaggtggatcgatcgcttctccgagctttgctgcgcatgcttcgaacactggat
ctgtacaaacaatcgttcgaggaagagtttttaactagtacaagtgtgcattatactcat
gaaagtatgtccttggtacgggctcttgagaccgtagagtttctgctatatatcgaaagg
cggctcagggaagaaaacgagagggttgatctatacttggatgagagcactagaacacct
ttgcttatgagagctgaaaagtgtatgatcagtgatcatatgcaggacattgttgataat
ggtctcgcatcgttgttgaacgataatcgggtgaaagatgtcacgagattatattcgctg
ctgagtagagtggagggaggagttgcactgctcaaaactgggttctccacctatattaag
aaggttggcaaagctatgattatggacacgcaacgagatcaaaccatggttgaagatttg
atggctttcaaggataaactggatgtttttgtggaaacttgttttggctccgaggacgaa
aaaatgaagttcgctcaagctgagaaggacgcatttgactatttcattaacacccgtgga
aataagccggctgaattgatcgctaaatatatggacgcaagacttcgaagtgctaataaa
gaggcatctgatgaacagttagaccagcttatgaacaaagttatcactctgtttcggttt
attcaaggaaaagacgtatttgaagtattctacaagaaagacctcgcaaagcgattactt
ctgggccgtagcgcctccgtggatgctgagaaaattatgctaagcaaactgagacaagag
tgcggtgccggtttcactcagaagctggagggcatgttccgagacatggaattgtcaaaa
gatttaggtgttgcattcagaaattgtcagtgttctcacgatgggacaatggccagcgta
cgaaaatgtacaggtgagggaaaattttcattagatacgattttatacaaaatagaatta
ggacttactatgatgacagtcactctaccgaagcagctgaatgcttgccttcagctgtat
gaacgattctatgactcgagacatactggtcgcaagctgcagtggcaacctcgactcggg
caatgtgttctcaaggctaattttagaactgggtgcgacaaagaattaaaagtatcgctc
ttccaagccatagttctgctcctttttaataaccagtcctcgtggacagcaacagacatt
atgatggccacgaaattagagcaaaaggagttcgtccgaactatggtgtcgctgtcctgt
gcgaaagtccgtgtgctagctaaaactcctatgaataaggagatcaaagacgatgacgtg
ttcactgttaacacggacatgaaagaaatgcgattccgtatccgcatctctgaagtacaa
atgaaggagacggaagaggaatacaaggccgtggaagaggaagtcaatcaagatcggcag
taccaaatagatgcagcgattgtacgcgtgatgaaaacacgcaaaaagctcaaccaccaa
ctgctgatctcagagttatttgcacaacttagattcccggttcgagcagccgatttgaaa
aagcgaataggctcgctcatggaaagagattatttgcggcgttgcgatgaagatccgaat
gcttatcaatatgtcgcctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (3)   
   Pfam (3)   
All databases (41)   

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