KEGG   NETWORK: N00351
Entry
N00351                      Network                                

Name
HPV E6 to extrinsic apoptotic pathway
Definition
E6 -| FADD
  Expanded
K21807 -| 8772
Class
nt06131 Apoptosis (viruses and bacteria)
nt06166 Human papillomavirus (HPV)
Type
Pathogen
Pathway
hsa05165  Human papillomavirus infection
Disease
H00030  Cervical cancer
Gene
8772  FADD; Fas associated via death domain
Perturbant
K21807 (E6)  E6; HPV protein E6
Reference
  Authors
Garnett TO, Duerksen-Hughes PJ
  Title
Modulation of apoptosis by human papillomavirus (HPV) oncoproteins.
  Journal
Arch Virol 151:2321-35 (2006)
DOI:10.1007/s00705-006-0821-0
Reference
  Authors
Filippova M, Parkhurst L, Duerksen-Hughes PJ
  Title
The human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis.
  Journal
J Biol Chem 279:25729-44 (2004)
DOI:10.1074/jbc.M401172200

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