KEGG   NETWORK: N00398Help
Entry
N00398                      Network                                

Name
HCMV IE2-86 to TNF-NFKB signaling pathway
Definition
hcmvIE2-86 -| NFKB
  Expanded
K22775 -| (4790+5970)
Class
nt06123 TNF signaling (viruses and bacteria)
nt06167 Human cytomegalovirus (HCMV)
Type
Pathogen
Pathway
hsa05163  Human cytomegalovirus infection
Disease
H00368  Cytomegalovirus infection
Gene
4790  NFKB1; nuclear factor kappa B subunit 1
5970  RELA; RELA proto-oncogene, NF-kB subunit
Perturbant
K22775  UL122; viral transcription factor IE2
Reference
  Authors
Hancock MH, Nelson JA
  Title
Modulation of the NFkappab Signalling Pathway by Human Cytomegalovirus.
  Journal
Virology (Hyderabad) 1:104 (2017)
Reference
  Authors
Taylor RT, Bresnahan WA
  Title
Human cytomegalovirus IE86 attenuates virus- and tumor necrosis factor alpha-induced NFkappaB-dependent gene expression.
  Journal
J Virol 80:10763-71 (2006)
DOI:10.1128/JVI.01195-06
Reference
  Authors
Rahman MM, McFadden G
  Title
Modulation of NF-kappaB signalling by microbial pathogens.
  Journal
Nat Rev Microbiol 9:291-306 (2011)
DOI:10.1038/nrmicro2539

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