KEGG   NETWORK: N00477
Entry
N00477                      Network                                

Name
EBV BHRF1 to crosstalk between extrinsic and intrinsic apoptotic pathways
Definition
BHRF1 -| BID
  Expanded
K19463 -| 637
Class
nt06131 Apoptosis (viruses and bacteria)
nt06165 Epstein-Barr virus (EBV)
Type
Pathogen
Pathway
hsa05169  Epstein-Barr virus infection
Disease
H00008  Burkitt lymphoma
H00007  Hodgkin lymphoma
H00054  Nasopharyngeal cancer
Gene
637  BID; BH3 interacting domain death agonist
Perturbant
K19463 (BHRF1)  BHRF1; EBV apoptosis regulator BHRF1
Reference
  Authors
Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM
  Title
Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.
  Journal
PLoS Pathog 6:e1001236 (2010)
DOI:10.1371/journal.ppat.1001236
Reference
  Authors
Fu Q, He C, Mao ZR
  Title
Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells.
  Journal
J Zhejiang Univ Sci B 14:8-24 (2013)
DOI:10.1631/jzus.B1200189

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