KEGG   NETWORK: N00528
Entry
N00528                      Network                                
Name
HCV core to extrinsic apoptotic pathway
Definition
Core -> CFLAR -| CASP8
  Expanded
K22271 -> 8837 -| 841
Class
nt06524 Apoptosis
nt06263 Hepatocellular carcinoma
nt06163 Hepatitis C virus (HCV)
Type
Pathogen
Pathway
hsa05160  Hepatitis C
Disease
H00048  Hepatocellular carcinoma
Gene
8837  CFLAR; CASP8 and FADD like apoptosis regulator
841  CASP8; caspase 8
Perturbant
K22271 (Core)  Core; HCV core protein
Reference
PMID:24788178
  Authors
Kim H, Ray R
  Title
Evasion of TNF-alpha-mediated apoptosis by hepatitis C virus.
  Journal
Methods Mol Biol 1155:125-32 (2014)
DOI:10.1007/978-1-4939-0669-7_11
Reference
PMID:16611896
  Authors
Saito K, Meyer K, Warner R, Basu A, Ray RB, Ray R
  Title
Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein.
  Journal
J Virol 80:4372-9 (2006)
DOI:10.1128/JVI.80.9.4372-4379.2006

  All links  
Pathway (1)   
   KEGG PATHWAY (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2)   
Literature (2)   
   PubMed (2)   
All databases (6)   

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