KEGG   NETWORK: N00920
Entry
N00920                      Network                                

Name
PRL-JAK-STAT signaling pathway
Definition
PRL -> PRLR -> JAK2 -> STAT5
  Expanded
5617 -> 5618 -> 3717 -> (6776,6777)
Class
nt06325 PRL signaling
Type
Reference
Pathway
hsa04917  Prolactin signaling pathway
Gene
5617  PRL; prolactin
5618  PRLR; prolactin receptor
3717  JAK2; Janus kinase 2
6776  STAT5A; signal transducer and activator of transcription 5A
6777  STAT5B; signal transducer and activator of transcription 5B
Reference
  Authors
Bernard V, Young J, Chanson P, Binart N
  Title
New insights in prolactin: pathological implications.
  Journal
Nat Rev Endocrinol 11:265-75 (2015)
DOI:10.1038/nrendo.2015.36
Reference
  Authors
Binart N, Bachelot A, Bouilly J
  Title
Impact of prolactin receptor isoforms on reproduction.
  Journal
Trends Endocrinol Metab 21:362-8 (2010)
DOI:10.1016/j.tem.2010.01.008
Reference
  Authors
Bachelot A, Binart N
  Title
Reproductive role of prolactin.
  Journal
Reproduction 133:361-9 (2007)
DOI:10.1530/REP-06-0299

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