KEGG   NETWORK: N01036
Entry
N01036                      Network                                

Name
L-DOPA generation
Definition
Tyrosine -- TH -> L-Dopa
  Expanded
C00082 -- 7054 -> C00355
Class
nt06422 Dopamine metabolism
nt06463 Parkinson disease
Type
Reference
Pathway
hsa00350  Tyrosine metabolism
hsa04728  Dopaminergic synapse
Gene
7054  TH; tyrosine hydroxylase
Metabolite
C00082  L-Tyrosine
C00355  3,4-Dihydroxy-L-phenylalanine
Reference
  Authors
Segura-Aguilar J, Paris I, Munoz P, Ferrari E, Zecca L, Zucca FA
  Title
Protective and toxic roles of dopamine in Parkinson's disease.
  Journal
J Neurochem 129:898-915 (2014)
DOI:10.1111/jnc.12686
Reference
  Authors
Jones DR, Moussaud S, McLean P
  Title
Targeting heat shock proteins to modulate alpha-synuclein toxicity.
  Journal
Ther Adv Neurol Disord 7:33-51 (2014)
DOI:10.1177/1756285613493469

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