KEGG   NETWORK: N01058
Entry
N01058                      Network                                

Name
Mutation-inactivated DJ1 to to p53-mediated transcription
Definition
DJ1* // TP53 => DUSP1
  Expanded
11315v1 // 7157 => 1843
Class
nt06440 Transcription
nt06463 Parkinson disease
Type
Variant
Pathway
hsa05012  Parkinson disease
Disease
H00057  Parkinson disease
Gene
11315  PARK7; Parkinsonism associated deglycase
7157  TP53; tumor protein p53
1843  DUSP1; dual specificity phosphatase 1
Variant
11315v1 (DJ1*)  PARK7 mutation
Reference
  Authors
Oh SE, Mouradian MM
  Title
Regulation of Signal Transduction by DJ-1.
  Journal
Adv Exp Med Biol 1037:97-131 (2017)
DOI:10.1007/978-981-10-6583-5_8
Reference
  Authors
Kato I, Maita H, Takahashi-Niki K, Saito Y, Noguchi N, Iguchi-Ariga SM, Ariga H
  Title
Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner.
  Journal
Mol Cell Biol 33:340-59 (2013)
DOI:10.1128/MCB.01350-12

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