KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103727317
Entry
103727317         CDS       T03372                                 
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase
  KO
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00790  Folate biosynthesis
ngi01100  Metabolic pathways
ngi01240  Biosynthesis of cofactors
ngi01523  Antifolate resistance
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    103727317 (Fpgs)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    103727317 (Fpgs)
Enzymes [BR:ngi01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.17  tetrahydrofolate synthase
     103727317 (Fpgs)
SSDB
Motif
Pfam: Mur_ligase_C
Other DBs
NCBI-GeneID: 103727317
NCBI-ProteinID: XP_008823382
Position
Un
AA seq 487 aa
MCLWKKSDWGRKGPGAREGSPDDPRSPGSSPHLVQVRERIRINGQPISPELFTKHFWRLY
HRLEETKDGSHAPMPAYFRFLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCG
VSSLGIDHTSLLGDTMEKIAWQKGGIFKPGVPAFTVPQPDGPLAVLRDRAQQISCPLYLC
PPLEALEEEGRPLMLGLEGEHQRSNAALALQLAHCWLQWQDHHDIWELKVSSPNTWWQLP
LAPRFQPTSRMQHGLRDTEWPGRTQVLRRGPLTWYLDGAHTTSSVQACVRWFHQSLQRNE
RPSGGPEVHVLLFNSTGDRDPAALLKLLQPCQFDYAVFCPNLTEVSATSNADQQNFTVTL
DQVLLRCLQHQQHWSCLSEKQASPDLWNTPSTEPDGPASLLLAPHPPHPTNTSSLVFSCI
SHALQWISQGRDPIFQPPSPPKGLFSHPTASSGASVLREAAAIHVLVTGSLHLVGGVLRL
LEPSLSQ
NT seq 1464 nt   +upstreamnt  +downstreamnt
atgtgtttatggaagaagtctgactggggcaggaaaggccctggggctcgggaaggaagt
cccgatgaccccagatctcccggcagctctcctcacctggtgcaggtgcgtgagcggatc
cgaatcaatgggcagcccatcagccctgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccaaggatggcagccacgcccccatgcccgcctacttccgcttc
ctcacactcatggccttccacatcttcctccaagagaaggtggacctggccgtggtagaa
gtgggcatcggtggggcttacgactgtaccaacatcattaggaagcctgtggtatgtgga
gtgtcctctcttggcattgaccacaccagcctgctaggagacaccatggagaagatagca
tggcagaaagggggcatctttaagcctggtgtccctgccttcactgtgccacagccagac
ggtcccctggccgtgctgagggatcgagcccagcagatctcatgtcctctctacctgtgt
cccccgctggaagccctggaggaggagggaaggccattgatgctgggcctggagggagaa
caccagcggtccaatgcagccttggccttgcagctggctcattgctggttacagtggcag
gaccaccatgatatctgggagctgaaggtgtctagcccaaacacatggtggcaactgccc
ctggcaccaaggttccaacccacatcccgtatgcaacatgggcttcgggacacggagtgg
cctggccggacacaggtgctgcggaggggaccccttacctggtacctggatggggcacac
accaccagcagcgtgcaggcctgtgttcgctggttccatcagtcgctgcagcgtaatgag
cgacccagtggtggacctgaggtacatgtcttgctcttcaactctactggagacagggac
ccagcagccctgctgaagttgctgcagccctgtcagtttgactatgctgtcttctgtccc
aacctgacagaggtgtcggccacaagtaatgcagaccagcagaacttcacagtgactctg
gaccaagtgctgctccgctgcctccaacaccagcagcactggagctgcctgagtgaaaag
caggccagcccggacctctggaacacccccagcacggaacctgacgggccagcctccctg
cttctggctccccaccctccccatcccaccaacaccagctcccttgtgttcagctgcatt
tcccacgccttgcagtggatcagccaaggccgggaccctatctttcagcccccaagtcct
ccaaagggcctgttcagccaccccactgccagcagtggggccagcgttctccgggaggct
gctgccatccatgtactggtcacaggaagcctgcatctggtgggtggagtcctgaggctg
ttggagccctccctgtcccagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (1)   
   Pfam (1)   
All databases (48)   

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