KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103736448
Entry
103736448         CDS       T03372                                 
Symbol
Gart
Name
(RefSeq) phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
  KO
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230  Purine metabolism
ngi00670  One carbon pool by folate
ngi01100  Metabolic pathways
ngi01523  Antifolate resistance
Module
ngi_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    103736448 (Gart)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    103736448 (Gart)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    103736448 (Gart)
Enzymes [BR:ngi01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.2  phosphoribosylglycinamide formyltransferase 1
     103736448 (Gart)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.1  phosphoribosylformylglycinamidine cyclo-ligase
     103736448 (Gart)
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.13  phosphoribosylamine---glycine ligase
     103736448 (Gart)
SSDB
Motif
Pfam: GARS_A Formyl_trans_N GARS_N AIRS_C GARS_C AIRS CPSase_L_D2 ATP-grasp_3 ATP-grasp Dala_Dala_lig_C ATP-grasp_2 ATP-grasp_4 RimK LUD_dom ATP-grasp_5
Other DBs
NCBI-GeneID: 103736448
NCBI-ProteinID: XP_008834168
UniProt: A0A8C6QMT9
Position
Un
AA seq 1010 aa
MAVRVLVIGSGGREHTLAWKLAQSHHVKEVLVAPGNAGTACCGKISNAAISINDHNVLAQ
FCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAEAARLESSKKFAKEFMDRHGIP
TARWKAFTKPEDACSFIMSANFPALVVKASGLAAGKGVIVAKNKEEACKAVQEIMQEKSF
GAAGETIVVEEFLEGEEVSCLCFTDGKTVAPMPSAQDHKRLLDGDQGPNTGGMGAYCPTP
QVPKELLLKIKSSVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLSTSLPVWLENHSAITVVMASKGYPGAYIKGVEITGFPEA
QALGLEVFHAGTALKDGKVVTSGGRVLTVTAMRENLLSALEEARRGLAAIKFEGAVYRTD
IGFRAIAFLQQPRALTYKESGVDIAAGNTLVKKIQPLAKATSRPGCSVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNRHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSTTEAVVAGVAKACGQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVVGVASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGHQSLGDLLLTPTK
IYSQSLLPIIRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDACTWRIPKVFSWLQWEG
QLSEEEMARTFNCGVGAALVVSKDQAEQILRDIRQHQEEAWVIGSVVLCPEDSPRVKVKN
LIETMQINRSVLTNGFLTDRFPTQPRKARVAVLISGTGSNLQALIDSTQDTKSSSHIVVV
ISNKAAVAGLEKAERAGIPTRVINHKLYKSRVEFDNAVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKVAEHKIFPAALQLVASGTVQLGENGKICWVKEK
NT seq 3033 nt   +upstreamnt  +downstreamnt
atggcagtccgagtccttgtaattggcagtggaggaagggaacatacactggcctggaaa
cttgcacagtctcatcatgtcaaagaagtgttggttgccccaggaaatgcaggcactgcc
tgctgtggaaagatttcaaatgctgccatctccatcaatgatcataatgtccttgctcaa
ttctgcaaagatgagaagattgaacttgtggttgttggaccagaggcccctctagctgct
ggaatcgttggggacctgacttctgcgggagtgcgatgctttggtcccacagcagaagca
gctcggttagagtccagtaaaaagtttgccaaagagtttatggaccgacatggaatccca
acagcacggtggaaagctttcaccaaacctgaagatgcctgtagctttattatgagtgca
aattttcctgctttggttgtgaaggccagtgggcttgcagctggaaagggggtgatagtt
gcaaagaacaaggaggaagcatgcaaagctgtacaggagatcatgcaagaaaaatctttt
ggagcagctggagaaacaattgttgttgaagaatttcttgaaggagaagaagtatcttgt
ctttgtttcactgatgggaagacggtggctcccatgccctcagcacaagaccataaacga
ttactggatggagatcagggccccaacacagggggaatgggagcctattgtccaacacct
caggttcctaaagagttattactaaaaattaaaagcagtgttcttcagaggacagtagat
ggcatgcagcaggagggtacgccttatactggaattctctatgctggtataatgctgacc
aaagatggcccaaaagttctggagtttaattgccgttttggtgatcccgagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttagatggcctg
ctgagtacatctctccctgtttggctagaaaaccacagtgccataactgttgtcatggca
agtaaaggttatcctggagcctacatcaagggtgtagagataacagggtttcctgaagca
caagctttaggactagaagtgttccatgcaggcactgccctcaaagatggcaaagtagtg
accagcgggggtagagtccttacagtcacagccatgcgggaaaatctcctatcagccctt
gaagaagccaggagaggactggctgctataaagtttgagggggcagtttataggacggac
attggcttccgtgccatagccttcctccagcagcccagggccctgacttataaggaatcg
ggggtagatattgcagccggaaatacgctagttaagaaaattcagcctttagccaaagct
acctcaagaccaggttgcagtgtggatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagatcgcccagctgtgcaataggcatgataccattggtcaggatttggttgcaatgtgc
gtaaatgacattctagcacaaggagcagagcccctcttcttccttgattacttctcctgt
ggaaaacttgacctcagtacgactgaagctgttgtagctggagttgctaaagcttgtggc
caagctggatgtgctctccttggtggggaaacagcagaaatgcctgacatgtatcctcct
ggagagtatgatcttgccgggtttgccgttggtgctatggagcgggatcaaaaactccct
cacctggaaaggatcaccgaaggggatgttgttgttggagtagcttcatctggtcttcac
agcaatggatttagccttgtgcggaaaattgtggcaaagtcttccctccagtactcctct
ccagcacctgatggttgtggtcaccagtctttaggagacttacttctcactccaaccaag
atctacagccaatcactgttacctatcatacgttcaggacatgtcaaagcctttgctcat
attactggaggaggactgctagaaaatattcccagagtgctccctcagaagtttggagtg
gatttagatgcctgcacctggaggatccctaaggtcttctcatggttacagtgggaagga
cagctctctgaagaagagatggccagaacatttaactgtggagttggagctgcactggtg
gtatccaaggaccaggcagagcagattctgcgtgatattcgacagcaccaggaagaagcc
tgggtaataggcagtgttgttctgtgtcccgaagattctcctcgtgtaaaagtcaagaat
ttgattgaaaccatgcaaataaacaggtcagtgttgacaaatggcttcctgacagatcgt
ttccctacccaaccaagaaaggcaagagtggctgtgctgatatctggaacaggatcaaat
ctccaagccctcatagacagtacacaggatacaaaaagttcttcacacattgttgttgtt
atctccaacaaagctgctgtggctggcttagaaaaagcagaaagagctggtattcccacc
agagtaattaatcataaattatataaaagtcgtgtggaatttgacaatgcagttgaccaa
gtccttgaagagttctctacagacatagtctgtcttgcaggatttatgagaattctgtct
ggcccttttgtcagaaaatggaatgggaaaatgctcaatatccacccatctttgctccct
tctttcaagggttcaaatgctcatgagcaggtcctggaagctggagtcacaatcactggg
tgcactgtacactttgtagctgaagacgtagatgctggacaaattatcttacaagaagca
gttcctgtgaagaggggtgacactgttgcaactttgtctgaaagagtaaaagtagcagaa
cataaaatctttcctgcagccctccagctggtggccagtgggactgtacagcttggagaa
aatggcaagatctgctgggtcaaagagaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (8)   
   RefSeq(nuc) (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (15)   
   Pfam (15)   
All databases (70)   

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