KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103743005
Entry
103743005         CDS       T03372                                 
Symbol
Pak1
Name
(RefSeq) p21 (RAC1) activated kinase 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04010  MAPK signaling pathway
ngi04012  ErbB signaling pathway
ngi04014  Ras signaling pathway
ngi04024  cAMP signaling pathway
ngi04062  Chemokine signaling pathway
ngi04360  Axon guidance
ngi04392  Hippo signaling pathway - multiple species
ngi04510  Focal adhesion
ngi04625  C-type lectin receptor signaling pathway
ngi04650  Natural killer cell mediated cytotoxicity
ngi04660  T cell receptor signaling pathway
ngi04666  Fc gamma R-mediated phagocytosis
ngi04810  Regulation of actin cytoskeleton
ngi05132  Salmonella infection
ngi05170  Human immunodeficiency virus 1 infection
ngi05205  Proteoglycans in cancer
ngi05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103743005 (Pak1)
   04012 ErbB signaling pathway
    103743005 (Pak1)
   04014 Ras signaling pathway
    103743005 (Pak1)
   04392 Hippo signaling pathway - multiple species
    103743005 (Pak1)
   04024 cAMP signaling pathway
    103743005 (Pak1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103743005 (Pak1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103743005 (Pak1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103743005 (Pak1)
   04650 Natural killer cell mediated cytotoxicity
    103743005 (Pak1)
   04660 T cell receptor signaling pathway
    103743005 (Pak1)
   04666 Fc gamma R-mediated phagocytosis
    103743005 (Pak1)
   04062 Chemokine signaling pathway
    103743005 (Pak1)
  09158 Development and regeneration
   04360 Axon guidance
    103743005 (Pak1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103743005 (Pak1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    103743005 (Pak1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103743005 (Pak1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103743005 (Pak1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ngi01001]
    103743005 (Pak1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ngi04131]
    103743005 (Pak1)
   03036 Chromosome and associated proteins [BR:ngi03036]
    103743005 (Pak1)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103743005 (Pak1)
Protein kinases [BR:ngi01001]
 Serine/threonine kinases: STE group
  STE20 family
   103743005 (Pak1)
Membrane trafficking [BR:ngi04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    103743005 (Pak1)
 Endocytosis
  Macropinocytosis
   Kinases
    103743005 (Pak1)
Chromosome and associated proteins [BR:ngi03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     103743005 (Pak1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT Kdo
Other DBs
NCBI-GeneID: 103743005
NCBI-ProteinID: XP_008842432
UniProt: A0A8C6QTT4
Position
Un
AA seq 544 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD
DDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaaataacggtttagacatccaagacaaacccccagcccctccaatgagaaacacc
agcactatgattggagctggcagcaaagacgccggaaccctaaaccacggctccaagcct
ctgcctccaaacccagaggagaagaagaagaaggaccgattttaccgctccatcttacct
ggagataaaacaaataagaagaaggagaaggagcggccagaaatttctcttccttcagat
tttgagcatacaattcatgttggttttgatgctgtcacaggggagtttacggggatgcca
gagcaatgggcccgcttgcttcaaacatcaaatatcactaagtcagagcagaagaaaaac
ccacaggctgttctggatgtgttggaattttataactctaagaagacctccaatagtcag
aagtacatgagctttacagataagtcagctgaagactataattcttctaacactttgaat
gtgaagactgtgtctgagaccccagcagtgccaccagtttcagaagatgaagatgatgac
gatgatgctaccccacctccagtgattgctccacgcccagagcacacaaaatctgtatat
acacgatctgtgatcgaaccacttcctgttactccaactcgtgatgtggctacatctccc
atttcacctactgagaataacaccactccgccagatgctttgactcggaatactgagaag
cagaagaagaagcctaaaatgtctgatgaggagatcttggagaaattacggagcatagtg
agtgtgggcgatcctaagaagaagtatacacggtttgagaagattggacaaggtgcttca
ggcaccgtgtatactgcaatggatgtggccacaggacaggaggtggccattaaacagatg
aatctccagcagcaaccgaagaaagagctgattattaatgagattctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagttaccttgtgggagatgaactatgg
gttgtcatggaatacttggctggaggctccctgacagatgtcgtgacagaaacctgtatg
gatgaaggccagatagcagctgtatgtcgtgagtgtctacaggctttggagttcctgcat
tcaaaccaagtcattcacagagacatcaagagtgacaatattctgctaggaatggatggc
tctgtcaagttaactgactttggattctgtgcacagatcacgccagagcagagcaaacgg
agcaccatggtaggaactccatattggatggcacccgaggttgtgacgcggaaggcctat
ggacccaaggttgacatctggtctctgggcatcatggccattgaaatgattgagggggag
cccccatacctcaatgaaaaccctttgagagccttgtacctcattgccaccaacgggacc
ccagagctgcagaacccagagaagctgtcggctattttccgggactttttgaaccgctgt
cttgagatggatgtggagaagaggggttcagccaaagagctactgcagcatcagttcctg
aagattgccaagcccctctccagcctcactccactgattgctgcagcaaaggaggcaacc
aagaacaatcactaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (9)   
   Pfam (9)   
All databases (53)   

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