KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103744649
Entry
103744649         CDS       T03372                                 
Symbol
Alk
Name
(RefSeq) anaplastic lymphoma receptor tyrosine kinase
  KO
K05119  anaplastic lymphoma kinase [EC:2.7.10.1]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi05200  Pathways in cancer
ngi05223  Non-small cell lung cancer
ngi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103744649 (Alk)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103744649 (Alk)
  09162 Cancer: specific types
   05223 Non-small cell lung cancer
    103744649 (Alk)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ngi01001]
    103744649 (Alk)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ngi04090]
    103744649 (Alk)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103744649 (Alk)
Protein kinases [BR:ngi01001]
 Receptor tyrosine kinases (RTK)
  ALK family
   103744649 (Alk)
CD molecules [BR:ngi04090]
 Proteins
  103744649 (Alk)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase MAM Gly_rich Ldl_recept_a FXa_inhibition
Other DBs
NCBI-GeneID: 103744649
NCBI-ProteinID: XP_008844703
Position
Un
AA seq 1622 aa
MQALGLRWLLLQLLSAAAWGFRASADQRAGFPVAGPPLQPREPLSYSRLQRKSLAVDFVV
PSLFRVYARDLLLPPPPSPSEPRTGGPEARGSLALDCAPLLRLLGPRLGVSWAAGTSSPS
SEGGPTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEAAAVGLLQFNLSELFS
WWIRHGEGRLRIRLMPEKKASEMGREGKLSAAIRASQPRLLFQIFGTGHSSLESPSSTPS
PDNFVWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHNHGNQSWSWRRVPSEE
ASQMDLLDGPEAEHSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCMLAVSVHRHLQP
SGRYIAQLLPHNEAGREILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAV
DFFALRNCSEGTSPGSKMALQSSFTCWNGTVLQLGHACDFHRDCAQGEDEGPLCSKLPAG
FYCNFEDDFCGWTQSILSPHMPQWQVRNLKNAQSQGRQGHALLLSTTDVPTSESATVTSA
TFPAPMKNSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMVWHVATNDASNEGLSLW
QWTVLSLLDVSDRFWLQIVVWWGQGSRATVAFDNISISLDCYLTISGEDKMPLNAAPKSR
NLFERNSHKDSKANVSGTTPIFDPTVHWLFTTCGASGPYGPTQAQCNNAYQNSNLSVVVG
NEGPLKGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDTLYILV
GQQGEDACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATFVFKMKDGVP
VPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKS
LLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDG
VSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLA
EDGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQS
PEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV
SGTPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFIL
LELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNC
LLTCAGTGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSF
GVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPN
FAIILERIEYCTQDPDVINTALPIEYGPVVEEEEKVPMRPKDPEGMPPLLVSPPAKHEDA
PAAPQQQSAQAAPAKAVKKAPAAGAGSSRVPRGPAAEGGHVNMAFAQSNPPAELHKAPGS
RNKPTSLWNPTYGSWFAEKPAKKHAPRAAAEPQGRAGAGCEGGWTRPGVPGPRGAGAALL
LEPSALTASMKEVPLFRLRHFPCGNVNYGYQQQGLPLEATAGAGHLEDSVLKNKSSATQP
GP
NT seq 4869 nt   +upstreamnt  +downstreamnt
atgcaagcccttgggctccggtggctgctgctacagctgctttcggcggcagcctggggc
ttccgcgcctcagcggatcagcgcgcgggcttcccggtcgcagggccgccactgcaaccc
cgggagccgctcagctactcgcgcctgcagaggaagagtctggcggtggacttcgtggtg
ccctcgctcttccgcgtttacgctcgagacctgctgctgccgccgccgccgtctccctcg
gagcctaggactggcgggccggaggcgaggggctcgctggctctggactgtgcccctctg
ctcagactgctggggccccggctcggggtctcctgggcagcaggcaccagctcgcccagt
tcagaaggaggtccgacgctgtccagggtgctgaagggaggctctgtgcgcaagctccgg
cgagccaagcagctggtgctggagctgggcgaggaggcgatcctggagggctgcgttggg
cccccagaggaggcagcggctgtggggttgctccagttcaacctcagcgagctgtttagc
tggtggattcgccacggcgaagggcggttgaggatccgcctgatgccggagaagaaggct
tcggaaatgggcagggagggaaagctgtcggcggctatccgtgcctcccagccccgcctt
ctcttccagatcttcgggaccggtcacagctccttggagtcaccctcaagcactccttct
cctgataattttgtgtggaatctgacctggataatgaaagattccttccctttcctgtcc
catcgcagtcgatatggtctggagtgcagctttgacttcccttgtgaactggaatactct
cctccattgcataatcatgggaaccagagctggtcctggcgtcgtgtgccctctgaggag
gcgtcgcagatggacttgttggatgggccagaggcagagcattctaaagagatgcccaga
ggctccttcctcctcctgaacacctctgcagattccaagcacaccatcctgagcccgtgg
atgaggagcagcagtgagcactgcatgctggctgtctcggtgcataggcatctacagcct
tctgggagatacattgctcagctactgccccacaatgaggctggaagagagattctcttg
gtgcctactccagggaagcatggctggacagtgctgcagggaaggatcgggcgcccagag
aatccattccgagtggccctggaatacatctccagtggaaaccgaagcttgtctgcagtg
gacttctttgccctgaggaactgcagtgaaggaacatccccaggctccaagatggccctg
cagagctccttcacttgttggaatgggacagttctccagctggggcatgcctgtgacttc
caccgggactgtgctcagggagaagacgagggaccgctgtgcagtaaacttcctgctggg
ttttactgcaactttgaagatgacttctgtggttggacccaaagcatactctcaccccac
atgccccagtggcaagtcaggaacctgaagaatgcccagtcccagggtcgccaaggtcat
gccctattgctcagtaccactgatgttcccacttctgaaagtgcgacggtgaccagtgct
acatttcctgcaccgatgaagaactctccttgtgagctccggatgtcctggctcatccgt
ggagttttgagaggaaatgtgtccttggtgctggtggagaacaaaaccggaaaggagcaa
agtcggatggtctggcatgttgccaccaatgatgcctcaaatgaaggcttgagcctatgg
cagtggacagtattgtctcttctcgatgtgtctgacaggttctggctgcagatagtcgta
tggtggggtcaaggatccagggcaacggtggcgtttgacaatatctccatcagcctggac
tgctacctcaccatcagtggggaggataagatgcccctgaatgcagcacccaaatccaga
aatctgtttgagagaaactcacacaaggattcaaaggccaatgtatcaggaacaactccc
atctttgaccctacagttcactggctgtttaccacatgtggggccagtggaccctatggc
cccacacaggcccagtgcaacaatgcctaccagaactccaatctgagcgtggtggtgggg
aacgaagggcccttgaagggcatccagatttggaaagtgccagccacagacacctacagc
atctcaggctatggagcagctggcgggaaaggcgggaagaacaccatgatgcggtcccat
ggagtatctgtgctgggtattttcaacctggagaaggatgacacgttatacatcctggtc
gggcaacagggagaggatgcctgtcctagtacaaaccaactaatccagaaagtttgcatc
ggagagaacaacgtgatagaagaagagatccgtgtgaacagaagcgtgcatgagtgggca
ggaggaggaggaggtgggggtggagccaccttcgtgtttaagatgaaagatggcgtgccg
gtacccctgatcattgcagctggcggtggtggcagggcctacggggccaagacagacacg
ttccacccagaaagattggagaataactcctcagttctagggctgaatggcaattccgga
gccgcaggtggtggaggcggctggaatgataacacttccttgctctgggccggaaagtct
ttgctggagggtgccacaggaggacattcctgcccccaggccatgaagaagtgggggtgg
gagacaagagggggtttcggagggggtggaggggggtgctcctcaggtggaggaggcgga
ggatatataggtggcaatgcagcatcaaacaatgacccagaaatggatggggaagatggg
gtttctttcatcagtccattgggtatcctgtacaccccagccttaaaagtgatggagggc
catggggaggtgaatatcaagcattacctaaactgcagtcactgtgaggtagatgaatgc
cacatggaccccgagagccacaaggtcatctgcttctgtgaccatgggaccgtactggct
gaggatggtgtctcctgcattgtgtcacccaccccggagccccatctgccactctcgctg
atcctctccgtcgtgacctctgccctggtggctgccctcgtcctggcattctctggcatc
atgattgtgtaccgccggaaacaccaggagctgcaagccatgcagatggaactgcagagc
cctgagtacaagctgagcaagctgcgcacctcgaccatcatgacggactacaaccccaac
tactgctttgccggcaagacttcatccatcagtgacctgaaggaggtgccacggaaaaac
atcaccctcatccggggcctgggccatggcgcatttggagaagtgtatgaaggccaggtg
tctggaacgcccaatgacccaagccccctacaagtggctgtaaagacgctgccagaagtg
tgttcagaacaggacgagctggatttcctcatggaagccctgatcatcagcaaattcaac
caccagaacatagtgcgctgcatcggagtgagtctgcaagccctgccccgcttcattctg
ctggagctcatggcaggtggagacctcaagtccttcctccgagagacacgccctcgccct
aaccagccctcctcactggccatgctggatcttctgcacgtggctcgggacattgcctgc
ggctgtcagtaccttgaggaaaaccacttcatccaccgggacattgctgctagaaactgc
cttttgacttgtgctggaactggaagaatagcaaagattggggactttgggatggctcga
gacatctacagagccagctactacagaaagggagggtgtgccatgctgccagtgaaatgg
atgcctccagaggccttcatggaaggaatatttacttctaaaactgacacatggtctttt
ggagtgttgctgtgggaaatattttctcttgggtatatgccataccccagtaaaagtaac
caggaagttctggagtttgtcaccagtggaggacggatggacccacctaagaactgcccc
gggcctgtataccggataatgactcagtgctggcagcatcaacctgaagacagacccaac
tttgccatcattttggagaggattgaatactgcacccaggacccagatgtcatcaacacc
gctctgcccatagagtatggcccggtggtggaagaggaggagaaagtacccatgaggccc
aaagaccccgaggggatgccccctctgctggtgtctccgcccgccaagcacgaggacgcg
cccgcggccccgcagcagcagtccgcccaggcggcgcccgccaaagcggtgaagaaggcc
ccggccgcgggcgcgggctccagccgggtccctcgaggccctgccgccgagggggggcac
gtgaacatggcgttcgctcagtccaacccgccggccgagctgcacaaggccccgggatcc
agaaacaagccgaccagcctgtggaacccgacctacggctcgtggttcgcggagaaaccg
gctaaaaagcacgctcctcgggcggccgcggagccgcagggccgggcaggtgcgggctgc
gagggcggctggacccggccgggcgtgcccgggccgcgaggagccggggcggcgctgctg
ctcgagccgtcggcgctgacagccagcatgaaggaggtgcctctgttcaggctgcgccac
ttcccctgcgggaacgtcaactatggctaccagcagcagggcctacccctggaggccacg
gcgggggccggccacttggaggacagtgttctgaaaaacaagagcagcgcgacccagccc
gggccctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (46)   
   KEGG ORTHOLOGY (1)   
   RefGene (42)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (63)   

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