KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103744942Help
Entry
103744942         CDS       T03372                                 

Gene name
Pla2g4b
Definition
(RefSeq) phospholipase A2 group IVB
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00564  Glycerophospholipid metabolism
ngi00565  Ether lipid metabolism
ngi00590  Arachidonic acid metabolism
ngi00591  Linoleic acid metabolism
ngi00592  alpha-Linolenic acid metabolism
ngi01100  Metabolic pathways
ngi04010  MAPK signaling pathway
ngi04014  Ras signaling pathway
ngi04072  Phospholipase D signaling pathway
ngi04217  Necroptosis
ngi04270  Vascular smooth muscle contraction
ngi04370  VEGF signaling pathway
ngi04611  Platelet activation
ngi04664  Fc epsilon RI signaling pathway
ngi04666  Fc gamma R-mediated phagocytosis
ngi04724  Glutamatergic synapse
ngi04726  Serotonergic synapse
ngi04730  Long-term depression
ngi04750  Inflammatory mediator regulation of TRP channels
ngi04912  GnRH signaling pathway
ngi04913  Ovarian steroidogenesis
ngi04921  Oxytocin signaling pathway
ngi05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    103744942 (Pla2g4b)
   00565 Ether lipid metabolism
    103744942 (Pla2g4b)
   00590 Arachidonic acid metabolism
    103744942 (Pla2g4b)
   00591 Linoleic acid metabolism
    103744942 (Pla2g4b)
   00592 alpha-Linolenic acid metabolism
    103744942 (Pla2g4b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103744942 (Pla2g4b)
   04010 MAPK signaling pathway
    103744942 (Pla2g4b)
   04370 VEGF signaling pathway
    103744942 (Pla2g4b)
   04072 Phospholipase D signaling pathway
    103744942 (Pla2g4b)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    103744942 (Pla2g4b)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103744942 (Pla2g4b)
   04664 Fc epsilon RI signaling pathway
    103744942 (Pla2g4b)
   04666 Fc gamma R-mediated phagocytosis
    103744942 (Pla2g4b)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103744942 (Pla2g4b)
   04913 Ovarian steroidogenesis
    103744942 (Pla2g4b)
   04921 Oxytocin signaling pathway
    103744942 (Pla2g4b)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    103744942 (Pla2g4b)
  09156 Nervous system
   04724 Glutamatergic synapse
    103744942 (Pla2g4b)
   04726 Serotonergic synapse
    103744942 (Pla2g4b)
   04730 Long-term depression
    103744942 (Pla2g4b)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103744942 (Pla2g4b)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    103744942 (Pla2g4b)
Enzymes [BR:ngi01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     103744942 (Pla2g4b)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B cPLA2_C2 C2
Motif
Other DBs
NCBI-GeneID: 103744942
NCBI-ProteinID: XP_008845030
Position
Un
AA seq 784 aa AA seqDB search
MALAKVPGTCLLTVRVLQAYGLPSKDLVTPADCYVTLWLPTASSHILQTRTVKNSRNPIW
NQNFHFQIHRQLKNIVELKVFDQDLLTKDDPVLSVLFDVGTLRAGESRRQSFSLNSQGEG
RLEVEFRLQTLTDCAEQLISNGILVARELSCLHVQLTRTGAPQGSEGRVQLVVPGACESP
QDFSVGTGSFRFHSPAFWEQELSIHLKDDPQEQLKVPLRALPSSQLVTLVFPTSQEPLMR
VQLKKEEGPRELAVRLDCGPCPEEQAFLSRRKQMVATALKQVLQLGQDLQEDEIPVVAVM
ATGGGIRAMTSLYGHLAGLRELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTK
LLKTQVTKSKLGALAPSQLRRYQQELAERARLGYPTCFTNLWSLINEALLHDEPHEHKLS
DQREALSRGQNPLPIYCALNSKEQGLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF
FMGRLVKQLPESRICFLEGIWSNLFAASLQDSLYWSSEPSQFWDRWAQDQASLDKEQVPH
LKIGEPPTTAGRIAGFFTDLLTKRPLAQATHNFLRGLHFHKDYFHHPHFSTWKATKLDGL
PNQLTPMEPHLCLLDVGYLINTSCPPLLQPTRDVDLILSLDYNLHGAFQQLQLLDRFCQQ
QGIPFPPILPSPEEQHRPGECHVFCDPAQPEAPAVLHFPLVNNSFREYSAPGVPRTQEEK
TAGEVNLSSSDSPYHYTKVTYSQEDVDKLLSLTHYNICNNQERLREALYQAVQRRRQRKQ
RRPE
NT seq 2355 nt NT seq  +upstreamnt  +downstreamnt
atggctctggcaaaggtgccagggacatgcctgctcactgtgcgtgtcctccaggcctat
ggcctgccttccaaggacctagtgacacctgctgactgctatgtgactctgtggctgccc
acggcctccagccacatactccagacacgcacagtcaagaacagcagaaaccccatctgg
aatcagaacttccacttccagatccacaggcagctcaagaatattgtggagctgaaagtc
tttgaccaggatctgttgaccaaagatgaccctgtgttgtcagtgctgtttgatgtgggg
acactacgagctggggagtctcggcgccagagcttctcactgaattcgcagggtgaggga
cggctggaagttgaatttcggctgcagactctgacagattgtgcagaacagctcatcagc
aatggcatcctggtggcccgggagctctcctgcttgcatgttcaactgacaaggacagga
gccccacagggatcagagggcagagttcaacttgtggttcctggggcctgtgagagccca
caggatttctctgtgggcactggctctttcagattccatagtccggccttctgggagcaa
gagctgagcattcatctgaaggatgacccccaggagcaattgaaggtaccactacgagcc
ctgccctcttcacagttggtgacactcgtcttccccacatcccaggagccactgatgagg
gtgcaactgaagaaggaagaaggaccaagggagctggctgtgcgactggactgtgggccc
tgcccggaagagcaggccttcctaagcaggagaaaacagatggtggccacagccctgaaa
caagtcctgcagctgggccaagacttacaggaggacgagatcccagtggtcgctgttatg
gccactggtggtgggatccgggcaatgacttccttatatgggcatctggctggcctcagg
gagctaggccttttggactgcatctcctacatcactggggcctcgggctccacctgggcc
ttggccaacctctatgaggatccagagtggtctcagaaggacctcgcaggtcctaccaag
ttgctgaagactcaggtgacaaagagcaagctgggtgcactggcccccagccagctgagg
cgataccagcaggagctggctgagcgcgctcgcctaggctatccgacctgcttcaccaac
ctatggtccctcatcaacgaggcactgctacatgatgagccccatgagcacaaactctct
gatcaacgggaggccctgagtcgaggccagaaccctctgcctatctactgtgccctcaac
agcaaggagcagggcctgacgacctttgaatttggggaatggtgcgagttctccccctac
gaagtcggcttccccaagtatggcgccttcatcccctctgagctctttggctctgagttc
ttcatggggcggctggtgaagcagctccctgagtcccgcatctgcttcctggaaggtatc
tggagcaacctatttgcagccagcctccaagacagcctgtattggtcctcagaacccagt
caattctgggaccgttgggcccaggatcaggccagcctggacaaagagcaggtcccccat
ctgaagatcggagaaccacccacaacagctggcaggattgctggatttttcactgacctc
ctgacaaagcgaccacttgcccaggccacccataattttctgcgtggcctccatttccac
aaggattatttccatcatcctcacttctccacttggaaggctaccaaactggatgggctc
cccaaccaactgactcccatggagcctcacctctgcctgttggatgttggctacttaatc
aataccagctgcccaccacttctgcagcccacacgggacgtggacctcatcctgtcactg
gactacaacctccacggagcctttcagcagttgcagctcctggaccgcttctgtcagcag
cagggcattccgttccctcctatcttacccagccctgaggagcagcatcggcctggggag
tgccatgtgttctgtgaccctgcccagccagaagccccagcagtgctgcatttccctctg
gtcaacaactccttcagggagtactctgcccctggggtaccacgaacacaggaggaaaag
acagctggagaagtgaatctgtcttcttctgactctccataccactacacaaaagtgacc
tacagccaagaggacgtggacaagctgctaagcctaacgcattacaacatctgcaataac
caggaaaggctgcgggaggccctgtaccaggccgtgcagcggcggaggcagcgcaagcag
cgaaggcccgagtga

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