KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103744945Help
Entry
103744945         CDS       T03372                                 

Gene name
Pla2g4e
Definition
(RefSeq) phospholipase A2 group IVE
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00564  Glycerophospholipid metabolism
ngi00565  Ether lipid metabolism
ngi00590  Arachidonic acid metabolism
ngi00591  Linoleic acid metabolism
ngi00592  alpha-Linolenic acid metabolism
ngi01100  Metabolic pathways
ngi04010  MAPK signaling pathway
ngi04014  Ras signaling pathway
ngi04072  Phospholipase D signaling pathway
ngi04217  Necroptosis
ngi04270  Vascular smooth muscle contraction
ngi04370  VEGF signaling pathway
ngi04611  Platelet activation
ngi04664  Fc epsilon RI signaling pathway
ngi04666  Fc gamma R-mediated phagocytosis
ngi04724  Glutamatergic synapse
ngi04726  Serotonergic synapse
ngi04730  Long-term depression
ngi04750  Inflammatory mediator regulation of TRP channels
ngi04912  GnRH signaling pathway
ngi04913  Ovarian steroidogenesis
ngi04921  Oxytocin signaling pathway
ngi05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    103744945 (Pla2g4e)
   00565 Ether lipid metabolism
    103744945 (Pla2g4e)
   00590 Arachidonic acid metabolism
    103744945 (Pla2g4e)
   00591 Linoleic acid metabolism
    103744945 (Pla2g4e)
   00592 alpha-Linolenic acid metabolism
    103744945 (Pla2g4e)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103744945 (Pla2g4e)
   04010 MAPK signaling pathway
    103744945 (Pla2g4e)
   04370 VEGF signaling pathway
    103744945 (Pla2g4e)
   04072 Phospholipase D signaling pathway
    103744945 (Pla2g4e)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    103744945 (Pla2g4e)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103744945 (Pla2g4e)
   04664 Fc epsilon RI signaling pathway
    103744945 (Pla2g4e)
   04666 Fc gamma R-mediated phagocytosis
    103744945 (Pla2g4e)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103744945 (Pla2g4e)
   04913 Ovarian steroidogenesis
    103744945 (Pla2g4e)
   04921 Oxytocin signaling pathway
    103744945 (Pla2g4e)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    103744945 (Pla2g4e)
  09156 Nervous system
   04724 Glutamatergic synapse
    103744945 (Pla2g4e)
   04726 Serotonergic synapse
    103744945 (Pla2g4e)
   04730 Long-term depression
    103744945 (Pla2g4e)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103744945 (Pla2g4e)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    103744945 (Pla2g4e)
Enzymes [BR:ngi01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     103744945 (Pla2g4e)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: cPLA2_C2 PLA2_B C2 CEP76-C2
Motif
Other DBs
NCBI-GeneID: 103744945
NCBI-ProteinID: XP_008845032
Position
Un
AA seq 878 aa AA seqDB search
MQSIPASREVDLEGMNQALEDHHSLGTNMFFPQNLQENQEDNRSGRNFSDFEDTQDLETP
KCLHLLSIASCNSQEGTSPCHLLTVRVIRMKNVRRADILSQTDCFVSLWLPTASQEKLRT
RTISNCLHPEWNESFTFQIQTQVKNVLELSVCDEDTVTPDDHLLTVLYDLSKLCFRNKTH
VKFPLNPEGMEELEVEFLLAESPSPPETLTTNGVLVSRQVSCLEVHAESRRQRQRKRKKT
KDLLVAVTDSFENTQCISPCMEPCCPNPACFHYPKYFQPQLLVEVPKSCWNCRFCCCGAH
KDGPVCQSLNCLSDGQAVTLPVGENFELHMKSTPCPDTLDVRLGFSLCQKEMEFLQKRKV
VVAEALRQVLQLEEDLPEDEVPLIAIMATGGGARSMTAMYGHLLGLQKLNLLNCSTYITG
LSGATWTMATLYSDPEWSSKNLEPAVFEARRHAVKDKMPALFPDQLCKCREELQQHSQEG
YRVTLTDFWGKLIEYCLGDKKNECKLSEQRAALCRGQNPLPIYLTINVKDDVSNQDFREW
FEFSPYEVGMQKYGAFIPTELFGSEFFMGRLMKRIPEPEMCHMLGLWSSIFSLNLLDAWN
LSHTSEEFFYRWTREKLQDIEDEPLLPEIPRCDANPLETTVVIPGSWLSNAFREILTHRP
FVSEFHNFLYGLQLHTDYLQDSQFSKWKDTVLDHLPNQLTQFTKHLYLLDTAFFVNSSYA
PLLRPERRVDLIIHLNYSAGSQTKHLKHTCEYCTTQNIPFPSYSIEEDDNNLKECYLMEN
PQELDAPIVAFFPLISDTFQKYKAPGVERSPEELELGQLNIYGPKSPYATKELTYSESAF
DKLVKLSEYNILNNKDKLLQALRLAVEKKKRMKSQCPS
NT seq 2637 nt NT seq  +upstreamnt  +downstreamnt
atgcagtctatcccagcctccagagaggtggacctggagggaatgaaccaagccttggaa
gaccatcatagtctggggaccaacatgttcttcccacagaacctacaagagaatcaagaa
gacaataggtcaggaagaaatttcagtgactttgaagacactcaggaccttgaaactccc
aagtgtctacatttactttccatagcctcctgcaactctcaggaggggacgtctccatgc
cacctgttgacagtgagggtcatccggatgaagaatgttcggcgggctgatattttgagc
cagacagactgctttgtgagcctctggctgcctactgcctctcaggaaaagctgaggacc
aggaccatctccaactgcctacacccagagtggaatgagagcttcaccttccagatccag
actcaagtgaagaatgtgctggagttgagtgtctgtgatgaagacacagtgacaccagat
gatcatctcttgacggttctctatgacctctctaagctctgctttcggaataaaacccac
gtgaagttcccactcaacccagagggaatggaagagctagaggtggagttcctgcttgca
gagagtccttctcctccggaaaccctcaccaccaacggcgtgcttgtgtctcgtcaagtc
tcttgcttggaggttcatgcagaatccaggaggcagaggcagaggaagaggaaaaaaact
aaagacctcctggtggcagtaacagactcctttgagaatacccagtgcatctcaccctgt
atggaaccctgctgccccaaccctgcctgcttccactaccctaagtacttccagccccag
ctacttgtagaagtgcctaagagctgctggaactgcaggttttgctgctgtggagcgcac
aaggatggccctgtctgtcaatccctcaattgcctttctgatggtcaggcagtgaccctg
cctgtgggcgaaaactttgaattacacatgaagtccacaccctgccctgacacgctggat
gtgcggctaggctttagcctgtgccaaaaagagatggagttcctgcagaagcggaaggtg
gtggtggctgaggcactgcggcaggtgctgcagctggaggaagacctgcctgaggatgag
gtaccactaatagccatcatggccactgggggtggagcaaggtctatgactgccatgtat
ggccacctgctggggctgcagaagctgaacctcctgaactgttccacttacatcaccggc
ttgtcaggtgccacctggaccatggctaccttgtacagtgaccctgagtggtcttccaaa
aacctggagcctgctgtctttgaggcccggagacatgctgtcaaagacaagatgcctgcc
ctgttcccagaccagctctgcaaatgccgagaagagctccaacagcacagccaggagggc
tacagggtcaccctaacagacttctggggcaagctgatcgagtattgtctgggggacaag
aaaaatgaatgcaaactgtcagagcagcgtgctgctttatgccggggccagaaccctctg
ccaatctacctcaccatcaatgtcaaggatgatgtaagcaaccaggatttcagagaatgg
ttcgagttctccccctatgaggtgggcatgcaaaagtatggggccttcatccctactgag
ctctttggctccgagttcttcatggggcggctgatgaagaggatccctgagccagagatg
tgccacatgctaggtttatggagcagcatcttctccctgaacctgcttgatgcctggaat
ttgtcacacacctcagaagagtttttttacagatggacaagggagaaactacaagacatt
gaagatgagccacttttgcctgaaatccccagatgtgatgctaaccctttggaaaccaca
gtagtaatcccagggtcatggctgtccaatgctttccgagagatcctcacacataggccc
ttcgtgtctgagttccacaacttcctgtatgggctgcaactgcacaccgactacttacag
gacagccagttctccaagtggaaagacacagtgctggaccacctcccaaaccagctgaca
cagtttacgaagcacttgtacctgctggacaccgcattcttcgtcaactccagctatgca
cccctcctcaggccagagagaagagttgacctcatcatccatctcaattattctgcagga
tcccagacaaagcacctgaaacacacatgtgagtactgcaccacacagaacatccccttc
cccagctactcgatcgaggaggatgacaacaatctcaaggaatgctacctgatggagaat
ccccaggagctggatgcccccattgtggctttcttcccactcatcagtgacaccttccag
aagtataaggctccaggtgtggaaagaagtcccgaggagctggagctgggccagctgaac
atctatggccccaaatctccctatgccaccaaagagctgacttactcggagtctgccttt
gacaaattggtaaagctgtcagagtacaatatcctcaataacaaagacaagctccttcag
gccttgagactggcggtggagaagaagaaacgcatgaagagccagtgtccctcctag

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