KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100579396Help
Entry
100579396         CDS       T03265                                 

Gene name
HSPA8
Definition
(RefSeq) heat shock cognate 71 kDa protein
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle03040  Spliceosome
nle04010  MAPK signaling pathway
nle04141  Protein processing in endoplasmic reticulum
nle04144  Endocytosis
nle04213  Longevity regulating pathway - multiple species
nle04612  Antigen processing and presentation
nle04915  Estrogen signaling pathway
nle05134  Legionellosis
nle05145  Toxoplasmosis
nle05162  Measles
Brite
KEGG Orthology (KO) [BR:nle00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    100579396 (HSPA8)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100579396 (HSPA8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100579396 (HSPA8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100579396 (HSPA8)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    100579396 (HSPA8)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    100579396 (HSPA8)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    100579396 (HSPA8)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    100579396 (HSPA8)
  09172 Infectious disease: viral
   05162 Measles
    100579396 (HSPA8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100579396 (HSPA8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nle01009]
    100579396 (HSPA8)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:nle03041]
    100579396 (HSPA8)
   03009 Ribosome biogenesis [BR:nle03009]
    100579396 (HSPA8)
   03110 Chaperones and folding catalysts [BR:nle03110]
    100579396 (HSPA8)
   04131 Membrane trafficking [BR:nle04131]
    100579396 (HSPA8)
   03051 Proteasome [BR:nle03051]
    100579396 (HSPA8)
   03029 Mitochondrial biogenesis [BR:nle03029]
    100579396 (HSPA8)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nle04147]
    100579396 (HSPA8)
Protein phosphatases and associated proteins [BR:nle01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     100579396 (HSPA8)
Spliceosome [BR:nle03041]
 Complex B
  Other components
   Prp19 complex
    100579396 (HSPA8)
 Complex C
   Prp19-CDC5 complex
    100579396 (HSPA8)
Ribosome biogenesis [BR:nle03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    100579396 (HSPA8)
Chaperones and folding catalysts [BR:nle03110]
 Heat shock proteins
  HSP70 / DNAK
   100579396 (HSPA8)
Membrane trafficking [BR:nle04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    100579396 (HSPA8)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    100579396 (HSPA8)
Proteasome [BR:nle03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    100579396 (HSPA8)
Mitochondrial biogenesis [BR:nle03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    100579396 (HSPA8)
Exosome [BR:nle04147]
 Exosomal proteins
  Proteins found in most exosomes
   100579396 (HSPA8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: HSP70 MreB_Mbl FGGY_C DDR HORMA MetOD2
Motif
Other DBs
NCBI-GeneID: 100579396
NCBI-ProteinID: XP_003253350
Ensembl: ENSNLEG00000007419
UniProt: A0A2I3HNE7
Position
15
AA seq 646 aa AA seqDB search
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
NT seq 1941 nt NT seq  +upstreamnt  +downstreamnt
atgtccaagggacctgcagttggtattgatcttggtaccacctactcttgtgtgggtgtt
ttccagcacggaaaagtagagataattgccaatgatcagggaaaccgaaccactccaagc
tatgtcgcctttacggacactgaacgattgatcggtgatgccgcaaagaatcaagttgca
atgaaccccaccaacacagtttttgatgccaaacgtctgattggacgcagatttgatgat
gctgttgtccagtctgatatgaagcattggcccttcatggtggtgaatgatgctggcagg
cccaaggtccaagtagaatacaagggagagactaaaagcttttatccagaggaggtatcc
tctatggttctgacaaagatgaaggaaattgcagaagcataccttgggaagactgttacc
aatgctgtggtcacagtgccagcttactttaatgactctcagcgtcaggctaccaaagat
gctggaactattgctggtctcaatgtacttagaattattaatgagccaactgctgctgct
attgcttacggcttagacaaaaaggttggagcagaaagaaacgtgctcatctttgacctg
ggaggtggcactttcgatgtgtcaatcctcacaattgaggatggaatctttgaggtcaag
tctacagctggagacacccacttgggtggagaagattttgacaaccgaatggtcaaccat
tttattgctgagtttaagcgcaagcataagaaggacatcagtgagaacaagagagccgta
agacgcctccgtactgcttgtgaacgtgctaagcgtaccctctcttccagcacccaggcc
agtattgagatcgattctctctatgaaggaatcgacttctatacctccattacccgtgcc
cgatttgaagaattgaatgctgacctgttccgtggcaccctggacccagtagagaaagcc
cttcgagatgccaaactagacaagtcacagattcatgatattgtcctggttggtggttct
actcgtatccccaagattcagaagcttcttcaagacttcttcaatggaaaagaactgaat
aagagcatcaaccctgatgaagctgttgcttatggtgcagctgtccaggcagccatcttg
tctggagacaagtctgaaaatgttcaagatctgctgctcttggatgtcactcctctttcc
cttggtattgaaactgctggtggagtcatgaccgtcctcatcaagcgtaataccaccatt
cctaccaagcagacacagaccttcactacctattctgacaaccagcctggtgtgcttatt
caggtttatgaaggcgagcgtgccatgaccaaggataacaacctgcttggcaagtttgaa
ctcacaggcatacctcctgcaccccgaggtgttcctcagattgaagtcacttttgacatt
gatgccaatggtatcctcaatgtctctgctgtggacaagagtacaggaaaagagaataag
attactatcactaatgacaagggccgtttgagcaaggaagacattgaacgtatggtccag
gaagctgagaagtacaaagctgaagatgagaagcagagggacaaggtgtcatccaagaat
tcacttgagtcctatgccttcaacatgaaagcaactgttgaagatgagaaacttcaaggc
aagattaatgatgaggacaaacagaagattctggacaagtgtaatgaaattatcaactgg
cttgataagaatcagactgccgagaaggaagaatttgaacatcaacagaaagagctggag
aaagtttgcaaccccatcatcaccaagctgtaccagagtgcaggaggcatgccaggagga
atgcctgggggattccctggtggtggagctcctccctctggtggtgcttcctcagggccc
accattgaagaggttgattaa

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