KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100585801Help
Entry
100585801         CDS       T03265                                 

Gene name
ATP1A2
Definition
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-2
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04022  cGMP-PKG signaling pathway
nle04024  cAMP signaling pathway
nle04260  Cardiac muscle contraction
nle04261  Adrenergic signaling in cardiomyocytes
nle04911  Insulin secretion
nle04918  Thyroid hormone synthesis
nle04919  Thyroid hormone signaling pathway
nle04925  Aldosterone synthesis and secretion
nle04960  Aldosterone-regulated sodium reabsorption
nle04961  Endocrine and other factor-regulated calcium reabsorption
nle04964  Proximal tubule bicarbonate reclamation
nle04970  Salivary secretion
nle04971  Gastric acid secretion
nle04972  Pancreatic secretion
nle04973  Carbohydrate digestion and absorption
nle04974  Protein digestion and absorption
nle04976  Bile secretion
nle04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    100585801 (ATP1A2)
   04022 cGMP-PKG signaling pathway
    100585801 (ATP1A2)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100585801 (ATP1A2)
   04918 Thyroid hormone synthesis
    100585801 (ATP1A2)
   04919 Thyroid hormone signaling pathway
    100585801 (ATP1A2)
   04925 Aldosterone synthesis and secretion
    100585801 (ATP1A2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    100585801 (ATP1A2)
   04261 Adrenergic signaling in cardiomyocytes
    100585801 (ATP1A2)
  09154 Digestive system
   04970 Salivary secretion
    100585801 (ATP1A2)
   04971 Gastric acid secretion
    100585801 (ATP1A2)
   04972 Pancreatic secretion
    100585801 (ATP1A2)
   04976 Bile secretion
    100585801 (ATP1A2)
   04973 Carbohydrate digestion and absorption
    100585801 (ATP1A2)
   04974 Protein digestion and absorption
    100585801 (ATP1A2)
   04978 Mineral absorption
    100585801 (ATP1A2)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100585801 (ATP1A2)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100585801 (ATP1A2)
   04964 Proximal tubule bicarbonate reclamation
    100585801 (ATP1A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nle04147]
    100585801 (ATP1A2)
Enzymes [BR:nle01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     100585801 (ATP1A2)
Exosome [BR:nle04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100585801 (ATP1A2)
  Exosomal proteins of other body fluids (saliva and urine)
   100585801 (ATP1A2)
  Exosomal proteins of colorectal cancer cells
   100585801 (ATP1A2)
  Exosomal proteins of bladder cancer cells
   100585801 (ATP1A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Hydrolase Cation_ATPase_N Hydrolase_3 Sigma70_r4
Motif
Other DBs
NCBI-GeneID: 100585801
NCBI-ProteinID: XP_003258741
Ensembl: ENSNLEG00000028357
UniProt: A0A2I3HW78
Position
12
AA seq 1020 aa AA seqDB search
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG
LTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME
DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKIQINA
EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI
CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS
RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF
NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM
ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDEVNFPTEKLCFVGLMSMIDPPRAAVPDAV
GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC
VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP
ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN
IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK
LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG
QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA
LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
NT seq 3063 nt NT seq  +upstreamnt  +downstreamnt
atgggccgtggggctggccgtgagtactcacctgccgccaccacggcagagaatgggggc
ggcaagaagaaacagaaggagaaggaactggatgagctgaagaaggaggtggcaatggat
gaccacaagctgtccttggatgagctgggccgcaaataccaagtggacctgtccaagggc
ctcaccaaccagcgggctcaggacattctggctcgagatgggcccaacgccctcacacca
cctcccacaacccctgagtgggtcaagttctgccgtcagcttttcggggggttctccatc
ctcctgtggattggggccatcctctgcttcctggcctacggcatccaggctgccatggag
gatgaaccatccaacgacaatctatatctgggtgtggtgctggcagctgtggtcattgtc
actggctgcttctcctactaccaggaggccaagagctccaagatcatggattccttcaag
aacatggtacctcagcaagcccttgtgatccgggagggagagaagatacagatcaacgca
gaggaagtggtggtaggagacctggtggaggtgaagggtggagaccgcgtccctgctgac
ctccggatcatctcttctcatggctgtaaggtggataactcatccttaacaggagagtcg
gagccccagactcgctcccccgagttcacccatgagaaccccctggagacccgcaatatc
tgtttcttctccaccaactgtgttgaaggcactgccaggggcattgtgattgccacaggc
gaccggacggtgatgggccgcatagctactctcgcctcaggcctggaggttgggcggacg
cccatagcaatggagattgaacacttcatccagctgatcacaggggtcgctgtattcctg
ggggtctccttcttcgtgctctccctcatcctgggctacagctggctggaggcagtcatc
ttcctcatcggcatcattgtggccaacgtgcccgagggacttctggccactgtcactgtg
tgcctgaccctgacagccaagcgcatggcacggaagaactgcctggtgaagaacctggag
gcggtggagacgctgggctccacgtccaccatctgctcggacaagacgggcaccctcacc
cagaaccgcatgaccgtcgcccacatgtggtttgacaaccaaatccatgaggctgacacc
accgaagatcagtctggggccacttttgacaaacgatcccctacgtggacggccctgtct
cgaattgctggtctctgcaaccgcgccgtattcaaggcaggacaggagaacatctccgtg
tctaagcgggacacagctggtgacgcctctgagtcagctctgctcaagtgcatcgagctc
tcctgtggctcagtgaggaagatgagagacagaaaccccaaggtggcagagattcctttc
aactcgaccaacaagtaccagctgtccatccacgagcgagaagacagcccccagagccac
gtgctggtgatgaagggggccccagagcgcattctggaccggtgctccaccatcctggtg
cagggcaaggagatcccacttgacaaggagatgcaagatgcctttcaaaatgcctacatg
gagctggggggacttggggagcgtgtgctgggattctgtcaactgaatctgccatctgga
aagtttcctcggggcttcaagttcgatacggatgaggtgaactttcccacggagaagctt
tgctttgtggggctcatgtctatgattgaccctccccgggctgctgtgccagatgctgtg
ggcaagtgccgaagcgcaggcatcaaggtgatcatggtaaccggggatcaccctatcaca
gccaaggccattgccaaaggcgtgggcatcatatcagagggtaacgagactgtggaggac
attgcagcccggctcaacattcccatgagtcaagtcaaccccagagaagccaaggcgtgc
gtggtgcatggctctgacctgaaggacatgacatcggagcagctcgatgagatcctcaag
aaccacacagagatcgtctttgctcgaacgtctccccagcagaagctcatcattgtggag
ggatgtcagaggcagggagccattgtggccgtgacgggtgacggggtgaacgactcccct
gcactgaagaaggctgacattggcattgccatgggcatctctggctctgacgtctctaag
caggcagccgacatgatcctgctggacgacaactttgcctccatcgtcacaggggtggag
gagggccgcctgatctttgacaacttgaagaaatccatcgcctacaccctgaccagcaac
atccccgagatcacccccttcctgctgttcatcattgccaacatccccctacctctgggc
actgtgaccatcctttgcattgacctgggcacagatatggtccctgccatctccttggcc
tatgaggcagctgagagtgatatcatgaagcggcagccgcgaaactcccagacagacaag
ctggtgaatgagaggctcatcagcatggcctatggacagatcgggatgatccaggcactg
ggtggcttcttcacctactttgtgatcctggcagagaacggtttcctgccatcacggcta
ctgggaatccgcctcgactgggatgaccggaccatgaatgatctggaggacagctacgga
caggagtggacctatgagcagcggaaggtggtggagttcacgtgccacacggcattcttt
gccagcatcgtggtggtgcagtgggctgacctaatcatctgcaagacccgccgcaactca
gtcttccagcagggcatgaagaacaagatcctgatttttgggctcctggaggagacggct
ttggctgcctttctctcttactgcccaggcatgggtgtagccctccgcatgtacccactc
aaagtcacctggtggttctgcgccttcccctacagcctcctcatcttcatctatgatgag
gtccgaaagctcatcctgcggcggtatcctggtggctgggtggagaaggagacctactac
tga

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