KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100590200
Entry
100590200         CDS       T03265                                 
Symbol
FLT1
Name
(RefSeq) vascular endothelial growth factor receptor 1 isoform X1
  KO
K05096  FMS-like tyrosine kinase 1 [EC:2.7.10.1]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04014  Ras signaling pathway
nle04015  Rap1 signaling pathway
nle04020  Calcium signaling pathway
nle04066  HIF-1 signaling pathway
nle04151  PI3K-Akt signaling pathway
nle04510  Focal adhesion
nle05202  Transcriptional misregulation in cancer
nle05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100590200 (FLT1)
   04014 Ras signaling pathway
    100590200 (FLT1)
   04015 Rap1 signaling pathway
    100590200 (FLT1)
   04066 HIF-1 signaling pathway
    100590200 (FLT1)
   04020 Calcium signaling pathway
    100590200 (FLT1)
   04151 PI3K-Akt signaling pathway
    100590200 (FLT1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100590200 (FLT1)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    100590200 (FLT1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100590200 (FLT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nle01001]
    100590200 (FLT1)
Enzymes [BR:nle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100590200 (FLT1)
Protein kinases [BR:nle01001]
 Receptor tyrosine kinases (RTK)
  VEGFR family [OT]
   100590200 (FLT1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ig_3 I-set ig Pkinase Ig_2 VEGFR-1-like_Ig-like V-set VEGFR-2_TMD Ig_6 Ig_4 C1-set Ig_5 V-set_CD47 Herpes_gE Haspin_kinase Adeno_E3_CR1 Marek_A
Other DBs
NCBI-GeneID: 100590200
NCBI-ProteinID: XP_003270266
Ensembl: ENSNLEG00000000456
UniProt: G1QIB2
Position
9:10622316..10818037
AA seq 1338 aa
MVSCWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHVMQAGQTLRLQCRGEAAHK
WSLPETVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET
ESAIYIFISDTGRPFIEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLETLIPD
GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV
KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRQRIDQSNSHANIFYSVLTIDK
VQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQRVLETVAGKRSYRLSMKVK
AFPSPEVVWLKDGLPTTEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSDVFKNLTA
TLIVNVQPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC
DFCSNNEDSFILDPDSNTGNRIDSITQRMAIIEGKNKTASTLVVADSRISGIYICIASNK
VGTVARNISFYITDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTM
HYSISKQKMAITKEHSITLNLTIMNVSMEDSGTYACRARNVYTGEEILQKKEITIRDQEA
PYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIER
VTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFI
RKMKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGK
VVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTK
QGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEKMEPGLEQGKKPRLDSV
TSSESFASSGFQEDKSLSDVEEEEDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIH
RDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKS
DVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRD
PKERPRFAELVEKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKEGISA
PKFNSGSSDDVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTW
TDSKPKASLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHISDGKRRFTYDNAELERKIAC
CSPPPDYNSVVLYSTPPI
NT seq 4017 nt   +upstreamnt  +downstreamnt
atggtcagctgctgggacaccggggtcctgctgtgcgcgctgctcagctgtctgcttctc
acaggatctagttcaggttcaaaattaaaagatcctgaactgagtttaaaaggcacccag
cacgtcatgcaagcaggccagacactgcgtctccaatgcaggggggaagcagcccataaa
tggtctttgcctgaaacggtgagtaaggaaagcgaaaggctgagcataactaaatctgcc
tgtggaagaaatggcaaacaattctgcagtactttaaccttgaacacagctcaagcaaac
cacactggcttctacagctgcaaatatctagctgtacctacttcaaagaagaaggaaaca
gaatctgcaatctatatatttattagtgatacagggagacctttcatagagatgtacagt
gaaatccccgaaattatacacatgactgaaggaagggagctcgtcattccctgccgggtt
acatcacctaacatcactgttactttaaaaaagtttccacttgaaactttgatccctgat
ggaaaacgcataatctgggacagtagaaagggcttcatcatatcaaatgcaacgtacaaa
gaaatagggcttctgacctgtgaagcaacagtcaatgggcatttgtataagacaaactat
ctcacacatcgacaaaccaatacaatcatagatgtccaaataagcacaccacgcccagtc
aaattacttagaggccatactcttgtcctcaattgtactgctaccactcccttgaacacg
agagttcaaatgacctggagttaccctgatgaaaaaaataagagagcttctgtaaggcaa
cgaattgaccaaagcaattcccatgccaacatattctacagtgttcttactattgacaag
gtgcagaacaaagacaaaggactttatacttgtcgtgtaaggagtggaccatcattcaaa
tctgttaacacctcagtgcatatatatgataaagcattcatcactgtgaaacatcgaaaa
cagcgggtgcttgaaaccgtagctggcaagcggtcttaccggctctctatgaaagtgaag
gcatttccctccccggaagttgtatggttaaaagatgggttacctacaactgagaaatct
gctcgctatttgactcgtggttactcgttaattatcaaggacgtaactgaagaggatgca
gggaattatacaatcttgctgagcataaaacagtcagatgtgtttaaaaacctcactgcc
actctaattgtcaatgtgcaaccccagatttatgaaaaggccgtgtcatcgtttccagac
ccggctctctacccactgggcagcagacaaatcctgacttgcaccgcatatggtatccct
caacctacaatcaagtggttctggcacccctgtaaccataatcattccgaagcaaggtgt
gacttttgttccaataatgaagactcctttatcctggatcccgacagcaacacaggaaac
agaattgatagcatcactcagcgcatggcaataatagaaggaaagaataagacggctagc
accttggttgtggctgactctagaatttctggaatctacatttgcatagcttccaataaa
gttgggactgtggcaagaaacataagcttttatatcacagatgtgccaaatgggtttcat
gttaacttggaaaaaatgccgacggaaggagaggacctgaaactgtcttgcacagttaac
aagttcttatacagagacgttacttggattttactgcggacagttaataacagaacaatg
cactacagtattagcaagcaaaaaatggccatcactaaggagcactccatcactcttaat
cttaccatcatgaatgtttccatggaagattcaggcacctatgcctgcagagccaggaat
gtatacacaggggaagaaatcctccagaagaaagaaattacaatcagagatcaggaagca
ccatacctcctgcgaaacctcagtgatcacacggtggccatcagcagttccaccacttta
gactgtcatgctaatggtgtccccgagcctcagatcacttggtttaaaaacaaccacaaa
atacaacaagagcctggaattattttaggaccaggaagcagcacgctgtttattgaaaga
gtcacagaagaggatgaaggtgtctatcactgcaaagccaccaaccagaagggctctgtg
gaaagttcagcatacctcactgttcaaggaacctcggacaagtctaatctggagctgatc
actctaacatgcacctgtgtggctgcgactctcttctggctcctattaaccctctttatc
cgaaaaatgaaaaggtcttcttctgaaataaagactgactacctatcaattataatggac
ccagatgaagttcccttggatgagcagtgtgagcggctcccttatgatgccagcaagtgg
gagtttgcccgggagagacttaaactgggcaaatcacttggaagaggggcttttggaaaa
gtggttcaagcatcagcatttggcattaagaaatcacctacatgccggactgtggctgtg
aaaatgctgaaagagggggccacggccagcgagtacaaagctctgatgactgagctcaaa
atcttgacccacattggccaccatctgaacgtggttaacctgctgggagcctgcaccaag
caaggagggcctctgatggtgattgttgaatactgcaaatatggaaatctctccaactac
ctcaagagcaaacgtgacttattttttctcaataaggatgcagcattacacatggagcct
aagaaagaaaaaatggagccaggcctggaacaaggcaagaaaccaagactagatagcgtc
accagcagcgagagctttgcgagctccgggtttcaggaagataaaagtctgagtgatgtt
gaggaagaggaggattctgacggtttctacaaggagcccatcactatggaagatctgatt
tcttacagctttcaagtggccagaggcatggagttcctgtcttctagaaagtgcattcat
cgggacctggcagcgagaaacattctgttatctgagaacaatgtggtgaagatttgtgat
tttggcctcgcccgagatatttataagaaccccgattatgtgagaaaaggagatactcga
cttcctctgaaatggatggctcctgaatctatctttgacaaaatctacagcaccaagagc
gacgtgtggtcttacggagtattgctgtgggaaatcttctccttaggtgggtctccatac
ccaggagtacaaatggatgaggacttttgcagtcgcctgagggaaggcatgaggatgaga
gctcctgagtactctactcctgaaatctatcagatcatgctggattgctggcacagagac
ccaaaagaaaggccaagatttgcagaactcgtggaaaaactaggcgatttgcttcaagca
aatgtacaacaggatggtaaagactacatcccaatcaatgccatactgacaggaaatagt
gggtttacatactcaactcctgccttctctgaggacttcttcaaggaaggtatttcagct
ccgaagtttaattcaggaagctccgatgatgtcagatatgtaaatgctttcaagttcatg
agcctggaaagaatcaaaacctttgaagaacttttaccaaatgccacctccatgtttgat
gactaccagggggacagcagcactctgttggcctctcccatgctgaagcgcttcacctgg
actgacagcaaacccaaggcctcgctcaagattgacttgagagtaaccagtaaaagtaag
gagtcggggctatctgatgtcagcaggcccagtttctgccattccagctgtgggcacatc
agcgacggcaagcgcaggttcacctacgacaacgctgagctggaaaggaaaattgcgtgc
tgctccccgcccccagactacaactcggtggtcctgtactccaccccacccatctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (18)   
   Pfam (18)   
All databases (54)   

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