KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100601385
Entry
100601385         CDS       T03265                                 
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb
  KO
K06476  integrin alpha 2B
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04015  Rap1 signaling pathway
nle04151  PI3K-Akt signaling pathway
nle04510  Focal adhesion
nle04512  ECM-receptor interaction
nle04611  Platelet activation
nle04613  Neutrophil extracellular trap formation
nle04640  Hematopoietic cell lineage
nle04810  Regulation of actin cytoskeleton
nle04820  Cytoskeleton in muscle cells
nle05165  Human papillomavirus infection
nle05200  Pathways in cancer
nle05222  Small cell lung cancer
nle05410  Hypertrophic cardiomyopathy
nle05412  Arrhythmogenic right ventricular cardiomyopathy
nle05414  Dilated cardiomyopathy
nle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100601385 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    100601385 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    100601385 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100601385 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    100601385 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    100601385 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100601385 (ITGA2B)
   04611 Platelet activation
    100601385 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    100601385 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100601385 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    100601385 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100601385 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100601385 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    100601385 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100601385 (ITGA2B)
   05414 Dilated cardiomyopathy
    100601385 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nle01009]
    100601385 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nle04147]
    100601385 (ITGA2B)
   04515 Cell adhesion molecules [BR:nle04515]
    100601385 (ITGA2B)
   04090 CD molecules [BR:nle04090]
    100601385 (ITGA2B)
Protein phosphatases and associated proteins [BR:nle01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     100601385 (ITGA2B)
Exosome [BR:nle04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100601385 (ITGA2B)
Cell adhesion molecules [BR:nle04515]
 Integrins
  Integrin alpha subunits
   100601385 (ITGA2B)
CD molecules [BR:nle04090]
 Proteins
  100601385 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3
Other DBs
NCBI-GeneID: 100601385
NCBI-ProteinID: XP_003282434
Ensembl: ENSNLEG00000000152
Position
19:31772848..31789811
AA seq 1040 aa
MARALCPLQALWLLEWVLRLLGPCAAPPAWALNLDPVQLTFYAGPNGSHFGFSLDFHKDS
HGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA
RQGLGASVVSWSDIIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN
TLSRIYKENNFGLDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPIADIFSSYRP
GILLWHVPSQSLSFDSSTPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTRSGTLGAVEI
LDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY
LFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLNRDGYNDVAVAAPYGGPSGGGQV
LVFLGQSEGLSSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLLVGAYGANQVAVYR
AQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ
LDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSL
NVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADN
VLELQMDTANEGEGAYEAELAVHLPQGAHYMWALSNVEGFERLICNQKKENETTRVVLCE
LGNPMKKNTQIGITMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQV
ELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQ
PSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPTPSPSPIHRAHHKRDRRQIFLPEPEQ
PSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHA
WFNVSSLPYAVPQLSLPRGEAQVRTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMW
KVGFFKRNRPPLEEDDEEGE
NT seq 3123 nt   +upstreamnt  +downstreamnt
atggccagagccttgtgtccactgcaagctctctggcttctggagtgggtgctgcggctc
ttgggaccttgtgctgcccctccagcctgggccttgaacctggacccagtgcagctcacc
ttctatgcaggccccaatggcagccactttggattttcactggacttccacaaggacagc
catgggagagtggccatcgtggtgggcgccccgcggaccctgggccccagccaggaggag
acgggcggagtgttcctgtgcccctggagggccgagggcggccagtgcccctcgctgctc
tttgacctccgtgatgagacccgaaatgtaggttcccaaactttacaaaccttcaaggcc
cgtcaaggactgggggcgtcggtcgtcagctggagcgacatcattgtggcctgcgccccc
tggcagcactggaacgtcctagaaaagactgaggaggctgagaagacgcccgtaggcagc
tgctttttggctcagccggagagcggccgccgcgccgagtactccccctgtcgcgggaac
accctgagccgcatttacaaggaaaataattttggcttggacaagcgttactgtgaagcg
ggcttcagctccgtggtcactcaggccggagagctggtgcttggggctcctggcggctat
tatttcttaggtctcctggcccaggctccaattgcggatattttctcgagttaccgccca
ggcatccttttgtggcacgtgccctcccagagcctctcctttgactccagcaccccagag
tacttcgacggctactgggggtactcggtggccgtgggcgagttcgacggggatctcaac
actacagagtatgtcgtcggtgcccccactcggagcgggaccctgggagcggtggaaatt
ttggactcctactaccagaggctgcaccggctgcgcggagagcagatggcgtcgtatttt
gggcattcagtggctgtcactgatgtcaacggggatgggaggcatgatctgctggtgggc
gctccactgtatatggagagccgggcagaccgaaaactggccgaagtggggcgtgtgtat
ttgttcctgcagccgcgaggcccccacgcgctgggtgcccccagcctcctgctgactggc
acacagctctatgggcgattcggctctgccatcgcacccctgggcgacctcaacagggat
ggctacaatgacgttgcagtggctgccccctacgggggtcccagtggcgggggccaagtg
ctggtgttcctgggtcagagtgaggggctgagctcacgtccctcccaggtcctggacagc
cccttccccacaggctctgcctttggcttctcccttcgaggtgccgtagacatcgatgac
aacggatacccagacctgctcgtgggagcttacggggccaaccaggtggctgtgtacaga
gctcagccagtggtgaaggcctctgtccagctactggtgcaagattcactgaatcctgct
gtgaagagctgtgtcctaccccagaccaagacacccgtgagctgcttcaacatccagatg
tgtgttggagccactgggcacaacattcctcagaagctatccctaaatgccgagctgcag
ctggaccggcagaagccccgccagggccggcgggtgctgctgctgggctctcaacaggca
ggcaccaccctgaacctggatctgggcggaaagcacagccccatctgccacaccaccatg
gccttccttcgagatgaggcagacttccgggacaagctgagccccattgtgctcagcctc
aatgtgtccctaccgcccacggaggctggaatggcccctgctgtcgtgctgcatggagac
acccatgtgcaggagcagacacgaatcgtcctggactgcggggaagatgacgtgtgtgtg
ccccagcttcagctcactgccagcgtgacgggctccccgctcctagttggggcagataat
gtcctggagctgcagatggacacagccaacgagggcgagggggcctatgaagcagagctg
gcagtgcacctgccccagggcgcccactacatgtgggccctaagcaacgttgagggcttt
gagagactcatctgtaatcagaagaaggagaatgagaccaccagggtggtgctgtgtgag
ctgggcaaccccatgaagaagaacacccagataggaatcacgatgttggtgagcgtgggg
aatctggaagaggctggggagtctgtgtccttccagctgcagatacggagcaagaacagc
cagaatccaaacagcaagattgtgctgctggacgtgccggtccgggcggaggcccaagtg
gagctgcgagggaactcctttccagcctccctggtggtggcggcagaagaaggtgagagg
gagcagaacagcttggacagctggggacccaaagtggagcacacctatgagctccacaac
aatggccctgggactgtgaatggccttcacctcagcatccacctccccgggcagtcccag
ccctccgacctgctctacatcctggatatacagccccaggggggccttcagtgcttccca
cagcctcctgtcaaccccctcaaggtggactgggggctgcccacccccagcccctctccc
attcaccgggcccatcacaagcgggatcgcagacagatcttcctgccagagcccgagcag
ccctcgaggcttcaggatccagttctcgtaagctgcgactcggcgccctgtactgtggtg
cagtgtgacctgcaggagatggcgcgcgggcagcgggccatggtcacggtgttggccttc
ctgtggctgcccagcctctaccagaggccactggatcagtttgtgctgcagtcgcatgca
tggttcaacgtgtcctccctcccctatgcggtgccccagctcagcctgccccgaggggaa
gctcaggtgcggacacagctgctccgggccttggaggagagggccattccaatctggtgg
gtgctggtgggtgtgctgggtggcctgctgctgctcaccatcctggtcctggccatgtgg
aaggttggcttcttcaagcggaaccggccacccctggaagaagatgatgaagagggggag
tga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (50)   

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