KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100603428
Entry
100603428         CDS       T03265                                 
Symbol
PIK3R4
Name
(RefSeq) phosphoinositide 3-kinase regulatory subunit 4 isoform X1
  KO
K08333  phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04136  Autophagy - other
nle04140  Autophagy - animal
nle04371  Apelin signaling pathway
nle05010  Alzheimer disease
nle05014  Amyotrophic lateral sclerosis
nle05016  Huntington disease
nle05017  Spinocerebellar ataxia
nle05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    100603428 (PIK3R4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100603428 (PIK3R4)
   04136 Autophagy - other
    100603428 (PIK3R4)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100603428 (PIK3R4)
   05014 Amyotrophic lateral sclerosis
    100603428 (PIK3R4)
   05016 Huntington disease
    100603428 (PIK3R4)
   05017 Spinocerebellar ataxia
    100603428 (PIK3R4)
   05022 Pathways of neurodegeneration - multiple diseases
    100603428 (PIK3R4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nle01001]
    100603428 (PIK3R4)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:nle04131]
    100603428 (PIK3R4)
Enzymes [BR:nle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100603428 (PIK3R4)
Protein kinases [BR:nle01001]
 Serine/threonine kinases: Other
  VPS15 family
   100603428 (PIK3R4)
Membrane trafficking [BR:nle04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    100603428 (PIK3R4)
 Autophagy
  Autophagosome formation proteins
   PI3K complex
    100603428 (PIK3R4)
SSDB
Motif
Pfam: Pkinase WD40 HEAT PK_Tyr_Ser-Thr NBCH_WD40 TCAD9 APH
Other DBs
NCBI-GeneID: 100603428
NCBI-ProteinID: XP_030672698
Ensembl: ENSNLEG00000002001
Position
8:19928875..19996085
AA seq 1376 aa
MTSLYCILTVLTPEVLAIMGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVAR
AKHREGLVVVKVFAIQDPTLPLTSYKQELEELKIRLNSAQNCLPFQKASEKASEKAAMLF
RQYVRDNLYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWV
LLTDFASFKPTYLPEDNPADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPL
VDLNSNQRTRGELKRAMDIFSAGCVIAELFTEGVPLFDLSQLLAYRNGHFFPEQVLNKIE
DRSIRELVTQMIHREPDKRLEAEDYLKQQRGNAFPEIFYTFLQPYMAQFAKETFLSADER
ILVIRKDLGNIIHNLCGHDLPEKAEGEPKENGLVILVSVITSCLQTLKYCDSKLAALELI
LHLAPRLSVEILLDRITPYLLHFSNDSVPRVRAEALRTLTKVLALVKEVPRNDINIYPEY
ILPGIAHLAQDDATIVRLAYAENIALLAETALRFLELVQLKNLNTENDPNNEEIDEVTHP
NGNYDTELQALHEMVQQKVVTLLSDPENIVKQTLMENGITRLCVFFGRQKANDVLLSHMI
TFLNDKNDWHLRGAFFDSIVGVAAYVGWQSSSILKPLLQQGLSDAEEFVIVKALYALTCM
CQLGLLQKPHVYEFASDIAPFLCHPNLWIRYGAVGFITVVAHQISTADVYCKLMPYLDPY
ITQPIIQIERKLVLLSVLKEPVSRSIFDYALRSKDITSLFRHLHMRQKKRNGSLPDCPPP
EDPAIAQLLKKLLSQGMTEEEEDKLLALKDFMMKSNKAKANIVDQSHLHDSSQKGVIDLA
ALGITGRQVDLVKTKQEPDDKRARKHVKQDSNVNEEWKSMFGSLDPPNMPQALPKGSDQE
VIQTGKPPRSESSAGICVPLSTSPQVPEVTTVQNKKPVIPVLSSTILPSTYQIRITTCKT
ELQQLIQQKREQCNAERIAKQMMENAEWESKPPPPGWRPKGLLVAHLHEHKSAVNRIRVS
DEHSLFATCSNDGTVKIWNSQKMEGKTTTTRSILTYSRIGGRVKTLTFCQGSHYLAIASD
NGAVQLLGIEASKLPKSPKIHPLQSRILDQKEDGCVVDMHHFNSGAQSVLAYATVNGSLV
GWDLRSSSNAWTLKHDLKSGLITSFAVDIHQCWLCIGTSSGTMACWDMRFQLPISSHCHP
SRARIRRLSMHPLYQSWVIAAVQGNNEVSMWDMETGDRRFTLWASSAPPLSELQPSPHSV
HGIYCSPADGNPILLTAGSDMKIRFWDLAYPERSYVVAGSTSSPSVSYYRKIIEGTEVVQ
EIQNKQKVGPSDDTPRRGPESLPVGHHDIITDVATFQTTQGFIVTASRDGIVKVWK
NT seq 4131 nt   +upstreamnt  +downstreamnt
atgacctcgttgtattgtatcctaaccgtactgaccccagaggtgcttgccattatggga
aatcagcttgctggcattgctccgtcccagatcctttctgtagagagttatttttcagat
attcatgactttgaatatgataaaagcctggggagtactcggttttttaaagttgctcga
gccaagcaccgagaaggcctggttgttgtgaaggtttttgcaattcaggatcccacattg
cctttaaccagctataaacaagagctggaggaactgaaaatcaggcttaattctgcacag
aattgtctacctttccagaaagcatcagaaaaagcatctgagaaagcagctatgctcttt
aggcagtatgtgcgagacaatctctatgatcgtatcagtacccgtccattcttgaataac
attgagaagcgctggattgctttccagatcctgacagctgtggaccaagcacacaaatct
ggagttcgtcatggggacatcaagactgagaatgtgatggtcaccagttggaattgggtt
cttctaactgactttgccagttttaagcccacttatcttccagaagacaacccggcagat
ttcaattatttctttgacacatcacggaggagaacttgctatattgctcccgaacgtttt
gttgacggtgggatgtttgccactgagttagaatatatgagagatccctcaactccactt
gtagacttaaatagcaatcagagaacaagaggagagttgaagagagcaatggatatcttt
tcagcaggttgtgtgatagctgagctttttacagaaggtgtaccattatttgatctctct
caacttttggcttatagaaatggacattttttccctgaacaagtgctaaataaaattgaa
gatcgcagtatcagagaattggtaactcagatgattcaccgtgagccagataaacgttta
gaggcagaagattacttaaaacagcagcgtggcaacgcctttcctgaaatattttacact
tttcttcagccctacatggcccagtttgccaaggaaacgttcctttctgcagatgagcgt
attctggttatacggaaggatttgggcaacattattcataatctctgtggacatgatctg
ccagaaaaagccgaaggagagcctaaggaaaatgggctggttatcttggtatctgttata
acatcctgcctacagacccttaaatactgtgattccaaactagctgctttggaacttatt
cttcatttggctccaagattaagtgttgaaatccttttggatcgtattactccatatctt
ttgcatttcagcaatgactctgttcctagggtgagggccgaagccttgaggacgttgacc
aaagttcttgctctcgtcaaagaggttcctcgtaatgatatcaatatttatccggaatac
attctgccaggcatagcccacttagcccaagatgatgctactatcgttagactagcctat
gctgaaaacatagctctgctggcagaaacagctctgagattcctggaattagtacagtta
aaaaatcttaatacggaaaatgaccccaataatgaagaaatagatgaagttacacatcca
aatggaaattatgacactgagctccaagccttacatgaaatggtccagcagaaagttgtt
actttgctaagtgaccctgaaaatattgtaaaacaaaccttgatggaaaatggaataaca
cggctgtgtgtattctttggacgtcagaaagccaatgatgttttgttgtcccacatgatt
actttcctaaatgataagaatgattggcatctacgtggagcattttttgatagtatagtt
ggtgttgctgcctatgttggctggcaaagctcctcgattctcaagcccctgctgcaacaa
ggtcttagtgatgctgaggaatttgtcattgtgaaagctctttatgcccttacttgtatg
tgccagttaggactgctacaaaaaccccatgtttatgaatttgccagtgatattgccccc
ttcctgtgtcatcccaatttatggatacgttatggtgccgtgggatttatcacagtggta
gctcatcaaataagtacagctgatgtctactgtaaactgatgccttatcttgacccatat
attacccaaccaataatacagattgaaagaaaacttgttctgctcagtgttttaaaggaa
ccagtaagccgttctatatttgattatgctttgaggtctaaagatattacgagcttgttc
agacatcttcacatgcgtcagaagaaacgaaatggttctcttcccgactgccctccgcca
gaggatcctgccatagcacagcttctgaagaagctgctctcacagggaatgacagaggaa
gaggaagacaaacttctggcactgaaagacttcatgatgaaatctaataaagcaaaggcc
aatatagtggaccagagccatcttcatgatagtagtcagaaaggtgtaattgacttggcg
gctttaggcataactgggagacaagttgatcttgttaaaaccaaacaagaaccagacgac
aaacgggccagaaaacatgtaaaacaagactcaaatgtaaatgaagaatggaaaagcatg
tttgggtcactggacccaccaaacatgccacaggccctacctaaagggagtgatcaggag
gtgattcagactgggaaacctcctcgttccgagtcctctgctggcatttgtgtccctttg
tcaacttctccacaggttccagaagtgacaactgtccaaaataaaaaaccagtaataccg
gttttaagtagtacaattttaccatccacctatcagattcgaattacaacttgtaaaact
gaacttcagcaactcatccagcaaaagcgggagcagtgcaatgctgagagaatagctaag
cagatgatggaaaatgctgaatgggagagtaaaccaccaccacctggatggcgtcctaaa
gggctgttagttgcccatcttcatgagcataaatctgctgtgaatcgaattagagtctct
gatgaacactcactttttgcaacatgttcaaatgatggcacagtgaaaatctggaacagt
caaaagatggaggggaagaccaccactaccagatctattcttacatacagccgaattgga
ggacgagtcaagacgctcacattctgccaaggctctcactatttagccatagcatctgat
aatggtgctgtccagcttcttggaattgaggcttctaagctgcccaagtctcctaaaatc
catcctctacaaagcagaattctagatcagaaggaggacggttgtgttgtggatatgcat
cacttcaactctggggcacagtctgttcttgcctatgccactgtgaatggctctctggtt
ggctgggaccttaggtcttcaagcaatgcgtggactttaaagcatgatttaaagtcgggc
ctcatcacttcctttgctgtggacatccaccaatgctggctctgcattggtacaagcagt
ggtaccatggcttgttgggacatgaggttccagttgccaatttcaagtcactgtcatcct
tccagggctcgaatcaggcgcctctcaatgcaccctctgtatcagtcctgggtgattgca
gctgttcagggcaacaacgaagtgtccatgtgggacatggagactggtgacagaagattt
actctctgggccagcagtgcaccaccactttctgaattacagccttctcctcatagcgtc
catggtatctactgtagtcctgcagatggaaatcctatcctgctaacagctggctcagat
atgaaaataaggttttgggacttggcttacccagaaaggtcctatgttgttgcaggaagt
actagttccccatctgtgtcctactacaggaaaataattgaaggcactgaagttgtccag
gaaattcagaataagcagaaagtaggaccaagtgatgacacccctcgaaggggcccagag
tccctgcccgtgggacatcacgacatcatcaccgatgtcgccacattccagacaacacag
ggcttcatcgtaactgcttctagagatgggattgtgaaggtgtggaaataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (7)   
   Pfam (7)   
All databases (46)   

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