KEGG   Neisseria meningitidis MC58 (serogroup B): NMB0416Help
Entry
NMB0416           CDS       T00027                                 

Gene name
murF
Definition
(RefSeq) UDP-MurNAc-pentapeptide synthetase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
nme  Neisseria meningitidis MC58 (serogroup B)
Pathway
nme00300  Lysine biosynthesis
nme00550  Peptidoglycan biosynthesis
nme01100  Metabolic pathways
nme01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:nme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    NMB0416 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    NMB0416 (murF)
 09160 Human Diseases
  09175 Drug resistance: Antimicrobial
   01502 Vancomycin resistance
    NMB0416 (murF)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:nme01011]
    NMB0416 (murF)
Enzymes [BR:nme01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     NMB0416 (murF)
Peptidoglycan biosynthesis and degradation proteins [BR:nme01011]
 Precursor biosynthesis
  Amino acid ligase
   NMB0416 (murF)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Motif
Other DBs
NCBI-GeneID: 902532
NCBI-ProteinID: NP_273464
UniProt: Q9K0Y8
Position
424872..426239
Genome map
AA seq 455 aa AA seqDB search
MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRAGDVFFALAGERFDAHDFVEDVLAA
GAAAVVVSREDCAAMDGALKVDDTLAALQTLAKAWRENVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDDAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
NAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDGIALIPQEDANMAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGDERAAVVLPVPGRHNVHNAAAAAALALAAG
LSLNDVAEGLKGFSNIKGRLNVKSGIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFV
MGDMGELGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDP
LIQVLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq 1368 nt NT seq  +upstreamnt  +downstreamnt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
agcaaacccgtgtcgcgcatcgtaaccgacagccgcgacatccgcgcgggcgatgtgttt
ttcgcattggcgggcgagcggtttgacgcgcatgattttgttgaagacgtattggctgct
ggtgcggcggcggttgtggtttcgcgcgaagattgtgctgcaatggatggcgcgttgaaa
gtcgatgacacgcttgccgcattgcaaacgctggcaaaggcgtggcgtgaaaatgtgaat
ccgtttgtgttcggcattaccggttcgggcggcaagacgacggtgaaggaaatgctggct
gcggtattgcgccgccgtttcggcgatgatgccgtgttggcgacggcaggcaacttcaac
aaccatatcggattgccgctgactttgttgaagttaaacgaaaaacaccgctatgccgtg
attgaaatgggcatgaaccatttcggcgaactggcggttttaacgcaaatcgccaaacca
aatgccgcattggtcaacaacgccatgcgcgcccatgtcggctgcggtttcgacggagtg
ggcgatattgccaaagcgaaaagcgagatttaccaaggtttatgttcagacggcattgca
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgttcacgcggaaaatattgtgctgaaaccg
ttgtcgtgcgaatttgatttggtgtgcggcgatgagcgcgccgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctggctttggctgcgggt
ttgagtttgaacgatgtggcggaaggtttgaaaggcttcagcaatatcaaaggccgtctg
aacgtcaaatccggaatcaagggcgcaaccctgattgacgatacttataatgcgaaccct
gacagcatgaaagctgcgattgacgtgttggcgcgtatgcctgcgccgcgtattttcgtg
atgggcgatatgggcgaactgggcgaactgggcgaggacgaagccgccgctatgcacgcc
gaagtcggcgcgtatgcccgcgaccaaggcatcgaagcggcttattttgtcggcgacaac
agcgtcgaagcggcggaaaaatttggcgcggacggtttgtggttcgccgccaaagacccg
ttgattcaagtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcg
cgctttatgcagatggaagaagtggtcgaggcattggaggataagtga

DBGET integrated database retrieval system