KEGG   Neisseria meningitidis MC58 (serogroup B): NMB1194Help
Entry
NMB1194           CDS       T00027                                 

Gene name
cysG-2
Definition
(RefSeq) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
nme  Neisseria meningitidis MC58 (serogroup B)
Pathway
nme00860  Porphyrin and chlorophyll metabolism
nme01100  Metabolic pathways
nme01110  Biosynthesis of secondary metabolites
nme01120  Microbial metabolism in diverse environments
Module
nme_M00846  Siroheme biosynthesis, glutamate => siroheme
Brite
KEGG Orthology (KO) [BR:nme00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    NMB1194 (cysG-2)
Enzymes [BR:nme01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     NMB1194 (cysG-2)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     NMB1194 (cysG-2)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     NMB1194 (cysG-2)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M
Motif
Other DBs
NCBI-GeneID: 903614
NCBI-ProteinID: NP_274220
UniProt: P95370
Position
complement(1196035..1197486)
Genome map
AA seq 483 aa AA seqDB search
MNYFPIFANLAGRPVLVVGGGAVAARKISLLLKAGAEVRVAAKHLNAELSALAAENKILW
LAEEFRAEHIRTVFLIIAASSDQALNRRVFHLAESCQKPVNVVDDRDHCSFIFPSVIDRN
PVQIAVSSSGSAPVLARLLRERLEALLPPSLGDMAEISGRWRDAVKGKLKSVTERRRFWE
KQFNGRFAALVKNRQNTLAERELAGQLEQSRQNDQGGSVSLVGAGPGDAGLLTLKGLQEI
QQADVVLYDALVSDGILSLVRRDAERIFVGKRARGERTPQEDTNALMVRLAREGRRVVRL
KGGDPFVFGRGGEELETLARHQIPFSVVPGITAAVGATAYAGIPLTHRDYAQSAVFVTGH
RKADAPDIEWQTLARSRQTLVIYMGALKAALIAERLQQHGRSPDTPAAVISQGTLPAQKT
ATGTLANLAELAETAPNPALIVIGEVVGLHEKLAWFGENGEGENRVGQTYPALGGLNAGQ
RAA
NT seq 1452 nt NT seq  +upstreamnt  +downstreamnt
gtgaattatttccctattttcgccaacctcgccggccgccccgtattggtcgtaggcggc
ggcgcggtcgccgcacgcaaaatcagcctgctgctgaaggcgggcgcagaggtcagggtt
gccgcaaaacacctgaatgccgaactctccgcgttggcggcggaaaacaaaatcctgtgg
cttgccgaagaatttcgtgccgaacacatccgcacggttttcctcatcattgcggcaagc
agcgaccaagccctcaaccggcgcgttttccatcttgccgaaagctgccaaaagccggtc
aacgtggtggacgaccgcgaccattgcagcttcatcttcccgtcggttatcgaccgcaac
ccggttcagattgccgtttccagctccggcagcgcgcccgtcctcgcccgactgctgcgt
gaaaggctggaagccctgctgccgccgtctttgggcgatatggcggaaatttcaggaagg
tggcgcgatgccgtcaagggcaaactgaaatccgttaccgaacgccgccgcttttgggaa
aagcagtttaacggacgtttcgccgccctcgtcaaaaaccggcaaaacacccttgccgaa
cgggaattggcaggccaattggaacaaagtcgtcaaaatgatcaaggcggctccgtctcg
ctggtcggcgcgggtcccggcgatgcggggctgctgacgctcaaagggctgcaggaaatc
cagcaggcagacgtggtgctttacgacgcgctggtttcagacggcatactgtccctcgtc
cgccgcgatgcggaacggatttttgtcggcaagcgcgcccggggcgagcgcaccccgcaa
gaggacaccaatgcgcttatggtcaggctggcccgcgaaggcaggcgcgtggtgcgtttg
aaaggcggagaccctttcgtgttcggacgcggcggcgaagaattggaaaccttggcacgc
catcagattccgttttcggtcgtccccggcattaccgccgccgtcggcgcgaccgcctat
gccggcatcccgctcacgcaccgcgattatgcccaaagtgcggttttcgtaaccggccac
cgcaaggcggatgcgcccgacatcgaatggcagaccctcgcccgcagccgccagaccttg
gtgatttatatgggtgcgctcaaagccgccctgattgccgaacggctgcaacagcacgga
cgctcgcccgacacgccggcagccgttatcagccaaggcacgctgccggctcaaaaaacc
gcaaccggcacgctcgccaaccttgccgaactcgccgaaaccgcgccgaatccggcattg
attgtcataggcgaagtggtggggctgcacgaaaaactcgcctggttcggtgaaaacggc
gaaggagaaaaccgggtcgggcagacgtatcccgcattgggcggactgaatgccggacaa
cgggcggcataa

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