KEGG   Numida meleagris (helmeted guineafowl): 110402541
Entry
110402541         CDS       T06015                                 
Symbol
DPYD
Name
(RefSeq) dihydropyrimidine dehydrogenase [NADP(+)] isoform X1
  KO
K00207  dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
Organism
nmel  Numida meleagris (helmeted guineafowl)
Pathway
nmel00240  Pyrimidine metabolism
nmel00410  beta-Alanine metabolism
nmel00770  Pantothenate and CoA biosynthesis
nmel00983  Drug metabolism - other enzymes
nmel01100  Metabolic pathways
Module
nmel_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
KEGG Orthology (KO) [BR:nmel00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    110402541 (DPYD)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    110402541 (DPYD)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    110402541 (DPYD)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    110402541 (DPYD)
Enzymes [BR:nmel01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.2  dihydropyrimidine dehydrogenase (NADP+)
     110402541 (DPYD)
SSDB
Motif
Pfam: DHO_dh Fer4_20 Fer4_21 Pyr_redox_2 NAD_binding_8 Dus Pyr_redox_3 Fer4_10 Fer4_7 Pyr_redox Fer4_2 Fer4_6 Fer4_9 Fer4 MurD-like_N Thi4 DAO FAD_binding_2
Other DBs
NCBI-GeneID: 110402541
NCBI-ProteinID: XP_021260409
Position
7:12584813..12918158
AA seq 1025 aa
MARVLSRDPVDIENLLALNPRTQSHATLHSTVTKKQVKKHWKRNSDKSCSNCEKLENNFD
DIKHTTLSERGALREAMRCLKCADAPCQKSCPTNLDIKSFIMSIANKNYYGAAKMIFSDN
PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMNIPQIRNPSLPPPE
DMPEAYHVKIALLGAGPASLSCASFLARLGYSNITIFEKQEYVGGLSASEIPQFRLPYDV
VNFEAELMKDLGVKIIFSKGLAVDGMTLSTLKEEGYEAVFIGIGLPEPNRDSIFQGLRMD
QGFYTSKDFLPLVAVASKPGMRACHSPLPSIHGTVIVLGAGDTAFDCATSALRCGARRVF
VVFRKGFTNIRAVPEEMELAKEEKCEFLPFLSPRKVVLRSGRIVAMEFVRTEQGNDGNWK
EDEDQVVHLKADVVISAFGSVLSDAKVREAMAPIKFNRWGLPEVDPETMQTSEPWVFAGG
DISGLANTTVESVNDGKQASWYIHRYIQSLYGAEVSVTPELPLFYTPIDLVDISVLMAGL
KFPNPFGIASATPATSSSMIRRAFEAGWGFAVTKTFSLDKDIVTNVSPRIVRGVTSGPVY
GPGQGSFLNIELISEKTAAYWCRSITELKGDFPNQILIASIMCSYSKDDWTELSKMAEAA
GADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVNI
AMAAQEGGADGVTATNTVSGLMGLKADGTPWPAVGAGLRTTYGGVSGNAIRPIALRAVSA
IARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIDDYCTGLRALLYL
KSIEELGDWNGQSPATMRHQKGKPVSGIADLIGKKLPHFGPYLELRKKITAENKIKLKEQ
GTATVLPEKKHFIPKKPIPAIKDVIGKALQYIGTYGELCNTEQAVALIDEEMCINCGKCY
MTCNDSGYQAIQFDAETHLPTVTDSCTGCTLCLSVCPIIDCIRMVPRTTTYVPQRGLPLA
LSPLC
NT seq 3078 nt   +upstreamnt  +downstreamnt
atggctcgggtgctgagccgggacccggtggacattgagaaccttctggcattaaatccc
cgaacacagagtcatgcaactcttcattcaactgtaacaaagaaacaagtcaagaagcat
tggaaaaggaattctgacaaaagttgttctaactgtgagaaactagaaaataattttgat
gacatcaagcacacgactcttagtgagcgaggagcacttcgagaagcaatgagatgctta
aagtgtgcagatgccccctgtcagaagagttgcccaactaatctggacatcaagtcattc
atcatgagtattgcgaacaagaactattatggagctgccaaaatgattttttctgacaat
ccacttggtctgacatgcggaatggtgtgtcccacatcagatctttgcgttggtggctgc
aatttgtatgccactgaggagggaccaattaatattggtggattgcagcagtttgctact
gaggtgttcaaagccatgaacattcctcagatcagaaatccttccttacctcctccagaa
gatatgcctgaagcttatcatgtgaagatagcacttcttggtgcaggacctgcaagttta
agttgtgcttcctttttggctcgactgggctattcaaacatcaccatatttgaaaagcag
gagtatgttggtggcttaagcgcatctgaaatccctcagttcagattgccatatgatgta
gtgaattttgaagctgagcttatgaaggatcttggagtgaagataatctttagtaaaggc
cttgcagtggatggaatgacactcagtaccttgaaagaagagggctatgaagcagtcttt
attggaataggtttaccagaaccaaatagagacagtatattccaagggctgcgaatggat
caaggattttacacatcaaaagacttcctacctttggtagccgtggcaagtaaaccaggg
atgcgtgcctgtcactctccattgccatcaatacatggaactgtgattgtacttggggca
ggagacactgcttttgactgcgcaacatctgctttacgctgtggagctcgtcgtgtgttt
gtggtcttcagaaagggcttcactaatatcagggctgtcccagaagagatggaacttgca
aaagaagagaagtgtgaatttctgcctttcctctcccctcggaaagttgtacttagaagt
ggacgtattgttgcaatggagtttgttcgaactgaacagggcaatgacggaaactggaaa
gaagatgaggatcaggttgttcatctgaaagctgacgtggtgatcagcgcctttggttca
gttttgagtgatgctaaagtcagagaggccatggcacctatcaagtttaacagatggggt
cttcctgaagtagatccagaaactatgcaaacgagtgaaccctgggtttttgcaggcggt
gatatcagtggtcttgctaacactacagtggaatcagtaaatgatggaaaacaagcctct
tggtacatacatagatacatacagtccttgtatggtgctgaagtttcagttactccagaa
ctaccactcttctatactcctatagatttagtagacatcagtgtattaatggctggactg
aagtttccaaatccttttggcattgccagtgcaacccctgctactagttcttcaatgatt
cggagagcttttgaagctggatggggctttgctgtcactaaaacattctccctggacaag
gatattgtgacgaatgtttctccaaggattgtgcgtggagttacttcggggcctgtctat
ggcccaggccaaggctcttttctaaacattgaactgatcagtgagaaaacagcggcatat
tggtgtagaagtattactgagctgaagggtgacttcccaaaccaaatcctgattgccagc
atcatgtgcagctatagcaaggacgactggactgaactttcaaaaatggctgaggctgct
ggtgcagatgcactggagttaaatctatcgtgtcctcatggcatgggggagagaggcatg
ggcctggcctgtgggcaggatccagagctggtgcggaacatctgccgctgggttagacaa
gctgttcagattcctttctttgccaagctgaccccaaatgtcactgatattgtgaatatt
gcgatggctgcgcaggaaggtggcgcagatggtgttacagccaccaacacagtgtcagga
ctgatgggactgaaagcagacggcacaccttggccagcagttggtgcaggactgaggacc
acatatggtggcgtgtcaggaaatgctattaggcccattgcgctccgtgcagtatctgct
atagcccgtgctcttccaggatttcctatcttagcaactggaggcatcgactctgctgaa
agtgggctccagtttctgcacagtggagcttctgttttacaggtgtgcagtgcaatccag
aatcaagatttcactgttattgatgactactgcactggactgcgagctcttctttacctg
aaaagcattgaggaacttggagactggaatgggcagagtcctgcaaccatgcgccatcag
aaaggaaaaccagtatctggaattgctgatctgataggaaagaaactaccccattttggg
ccttacctggaactacgcaaaaaaattacagctgagaacaagattaaactgaaggaacaa
ggtacagctactgtgcttcctgaaaaaaagcatttcattccaaagaagcccattccagca
atcaaggatgtaattggaaaagcactgcagtatattggaacatatggtgagctctgcaac
acggagcaagctgtggctctgattgacgaggaaatgtgtatcaactgtggcaaatgttac
atgacctgtaatgattctggctaccaggcaatccagttcgatgctgaaacccacctgccc
acggtcaccgacagctgcacgggctgcaccctgtgcctgagtgtctgccccatcatcgac
tgcatccgcatggttcccaggaccaccacgtacgtgccccagcgagggctgcccctggcc
ctgagccccctgtgctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (11)   
   RefSeq(pep) (11)   
DNA sequence (13)   
   RefSeq(nuc) (11)   
   GenBank (1)   
   EMBL (1)   
Protein domain (18)   
   Pfam (18)   
All databases (67)   

Download RDF
DBGET integrated database retrieval system