KEGG   Numida meleagris (helmeted guineafowl): 110405798
Entry
110405798         CDS       T06015                                 
Symbol
SMURF1
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF1 isoform X1
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
nmel  Numida meleagris (helmeted guineafowl)
Pathway
nmel04120  Ubiquitin mediated proteolysis
nmel04137  Mitophagy - animal
nmel04144  Endocytosis
nmel04340  Hedgehog signaling pathway
nmel04350  TGF-beta signaling pathway
nmel04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:nmel00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    110405798 (SMURF1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    110405798 (SMURF1)
   04350 TGF-beta signaling pathway
    110405798 (SMURF1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    110405798 (SMURF1)
   04137 Mitophagy - animal
    110405798 (SMURF1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    110405798 (SMURF1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:nmel04131]
    110405798 (SMURF1)
   04121 Ubiquitin system [BR:nmel04121]
    110405798 (SMURF1)
   03029 Mitochondrial biogenesis [BR:nmel03029]
    110405798 (SMURF1)
Enzymes [BR:nmel01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     110405798 (SMURF1)
Membrane trafficking [BR:nmel04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    110405798 (SMURF1)
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    110405798 (SMURF1)
Ubiquitin system [BR:nmel04121]
 Ubiquitin ligases (E3)
  HECT type E3
   110405798 (SMURF1)
Mitochondrial biogenesis [BR:nmel03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    110405798 (SMURF1)
SSDB
Motif
Pfam: HECT WW C2
Other DBs
NCBI-GeneID: 110405798
NCBI-ProteinID: XP_021267154
Position
13:complement(4498876..4542318)
AA seq 817 aa
MVAPRRLSSRALTSRPETRGGAEAERRRCPGRAGSGWRRRLRRAAAAAGPAAGGARRAAG
GSAGPHGVARGRGLISPRGAMSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKV
VVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRL
LSNAISRLKDTGYQRLDLCKLNPTDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEG
FPIFRTVYEDSGPGRPLSCFMEEPAPYTDTTGAAGGGNCRFVESPSQDQRLQAQRLRTPE
VRGHVQTPQNRPHGHQSPDLPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNC
DELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQQPLPAPNE
GSLEEGEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMR
PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSS
INPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLV
WILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNIPVTEENKKEYVRLYVNWRFMRGI
EAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCMADSNIVK
WFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLP
KAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE
NT seq 2454 nt   +upstreamnt  +downstreamnt
atggtggcgccgcgccgcctctcctcccgcgcgctgacgtcacgccccgagacgcggggc
ggggctgaggcggagcggaggcgctgtccgggccgggccgggtcgggctggcggcggcgg
ctgaggcgggcggcggcggcggcgggtccggccgcgggcggagcgcggagagcggccggg
ggttcagcaggcccgcatggggttgcgcggggccgcgggttgatctcgccgcggggcgcg
atgtcgaaccccgggacgcgtcggaacggctccagcatcaagatccgcctcacagtatta
tgtgccaagaatcttgcaaagaaagatttcttcagacttcctgacccgtttgcaaaagta
gttgttgatgggtcaggtcagtgccactcaactgacactgtgaagaacacgttggacccc
aaatggaaccagcattatgatctatatgttgggaagacagattccataaccatcagtgta
tggaaccataaaaaaatccacaagaaacagggagctggcttcctggggtgtgtccgactc
ctctccaatgccatcagcaggctaaaagatactggataccagcgtttggatctatgcaaa
ctaaatcccacggataccgatgccgtacgaggccaaatagtggtcagtttacagacacgg
gacagaataggcaccggaggttctgtagtagactgcagagggcttttggagaatgaaggt
ttccccattttcagaacggtttatgaagattccggaccggggaggccactgagctgtttt
atggaagaaccagcaccctacacagacactacgggggctgctggtggaggcaattgtcgc
tttgtagagtcccccagtcaagatcagaggcttcaggcacagcgacttcggactcctgaa
gtcagaggtcatgtacagacaccccagaacagaccgcatggtcaccagtctcctgacctg
cctgaaggctatgaacaaagaacaacggtacagggacaggtttattttttgcacacgcag
actggagttagcacatggcatgaccctaggataccaagagaccttaacagtgtgaattgt
gatgaactaggacctctgcctccaggttgggaagttagaagtactgtttcaggaagaata
tattttgtagatcataacaacagaaccacacaattcacagatccacgactacatcacatc
atgaaccatcaatgccagctaaaagagcccagccagcagcctctgccagctccaaatgag
gggtccctggaagagggtgaggagttgcctgcacagagatacgaaagagacttggtgcaa
aagctgaaagttcttagacatgagctctcccttcagcaaccgcaggcaggtcactgccga
attgaagtatccagagaggaaatatttgaggaatcctaccgtcagataatgaagatgagg
ccaaaggatttgaaaaagaggcttatggtaaaatttcgaggcgaggaaggcctggattat
ggaggagtagcaagagaatggttgtatttactgtgccatgaaatgctgaatccgtactat
ggactcttccagtactctacagataatatttacatgctgcaaatcaatccagactcctct
atcaatcctgaccatttgtcttatttccattttgttggtcggataatgggtttggctgtg
ttccatggacactatatcaatggagggttcacagttcccttttataaacagctcctgggg
aaacccattcagctctctgatctggaatctgttgacccagaactacacaaaagtttagtc
tggattctagagaacgatatcaccccggttctggaccatactttctgtgtggaacacaat
gcttttgggcggattttacagcacgaactcaaacccaacggcaggaacattccagtgaca
gaagagaacaagaaagaatatgtcaggttgtatgtaaactggcgatttatgagaggcata
gaagcacagttcttggctctgcagaaaggttttaatgaacttattccccaacatctcctc
aagccttttgaccagaaggaacttgagctaatcataggaggcctggataagatagacctg
aatgactggaagtcaaacacacgtctaaagcactgcatggcagatagcaatattgtgaag
tggttctggcaagcagtggaaacatttgatgaagaaagaagggcaaggcttttgcagttt
gtgacgggttcgacgcgtgtcccacttcaaggtttcaaggctttacaaggttctacaggc
gctgcaggacccagactgtttaccatccatttaatagatgcaaacacagacaaccttcca
aaagcccacacttgctttaaccggattgacatcccgccttatgagtcatatgagaagctt
tacgagaagctgttgacagctgtggaagagacatgtgggtttgctgtggagtga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (7)   
   RefSeq(nuc) (5)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (31)   

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