KEGG   Neisseria meningitidis M01-240149 (serogroup B): NMBM01240149_1046
Entry
NMBM01240149_1046 CDS       T01930                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
nmm  Neisseria meningitidis M01-240149 (serogroup B)
Pathway
nmm00290  Valine, leucine and isoleucine biosynthesis
nmm00620  Pyruvate metabolism
nmm01100  Metabolic pathways
nmm01110  Biosynthesis of secondary metabolites
nmm01210  2-Oxocarboxylic acid metabolism
nmm01230  Biosynthesis of amino acids
Module
nmm_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:nmm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    NMBM01240149_1046 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NMBM01240149_1046 (leuA)
Enzymes [BR:nmm01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     NMBM01240149_1046 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ADY97628
Position
complement(1195087..1196640)
AA seq 517 aa
MTQANRVIIFDTTLRDGEQSPGAAMTKEEKIRVARQLEKLGVDIIEAGFAAASPGDFEAV
NAIAKTITKSTVCSLSRAIERDIRQAGEAVAPAPKKRIHTFIATSPIHMEYKLKMKPKQV
IEAAVKAVKIAREYTDDVEFSCEDALRSEIDFLAEICGAVIEAGATTINIPDTVGYSIPY
KTEEFFRELIAKTPNGGKVVWSAHCHNDLGLAVANSLAALKGGARQVECTVNGLGERAGN
ASVEEIVMALKVRHDLFGLETGIDTTQIVPSSKLVSTITGYPVQPNKAIVGANAFSHESG
IHQDGVLKHRETYEIMSAESVGWSANRLSLGKLSGRNAFKTKLADLGIELESEEALNAAF
ARFKELADKKREIFDEDLHALVSDEMGNMNTESYKFISQKISTETGEEPRADIVFSIKGE
EKRASATGSGPVDAIFKAIESVAQSGATLQIYSVNAVTQGTESQGETSVRLARGNRVVNG
QGADTDVLVATAKAYLSALSKLEFSAAKPKAQGSGTI
NT seq 1554 nt   +upstreamnt  +downstreamnt
atgacacaggccaaccgcgttatcattttcgacaccaccctgcgcgacggcgagcagtcg
cccggcgctgctatgaccaaagaggaaaaaatccgcgtcgcccgccagctggaaaaattg
ggtgtggacatcatcgaagcgggttttgccgctgccagcccgggcgatttcgaggcggtc
aatgcgattgcgaaaaccattaccaaatcaacggtctgttcattgtcccgcgccatcgag
cgggacatccgtcaggcgggtgaggccgttgcgcccgcgccgaaaaaacgcatccacacc
ttcatcgccaccagccccatccatatggagtacaaattgaagatgaagccgaagcaggtg
attgaggcggcggtcaaagcggtgaaaatcgctcgtgaatacaccgacgatgtggaattt
tcctgcgaagacgcgttgcgttcggaaatcgatttccttgccgaaatctgcggcgcggta
attgaagcgggcgcgaccaccatcaatattcccgataccgtcggctattccatcccgtac
aaaaccgaagaatttttccgcgaactgattgccaaaacgcccaacggcggcaaagtcgtt
tggtcggcacactgccacaacgatttgggcttggcggttgccaattcgcttgccgcatta
aaaggcggtgcgcgtcaggtggaatgtactgtcaacggcttgggcgaacgtgcaggcaat
gcttcggttgaagaaatcgtgatggcgttgaaagtgcgccacgacttgttcggcttggaa
accggcatcgataccacgcaaatcgtgccttcgtccaaactggtgtccaccattacgggc
tatcccgtgcagcccaacaaagccattgtcggtgccaatgccttttcgcatgaatcgggc
atccatcaggacggggtgctgaaacaccgcgaaacttacgagattatgtctgccgaatcg
gtcggttggtcggctaaccgattgagcttgggcaaattgtccggccgcaacgccttcaaa
accaagctggcggatttgggcatcgagttggaaagcgaagaggcactgaacgcggcattt
gcacgcttcaaagaactcgccgacaaaaaacgcgaaatcttcgatgaagacctgcacgcg
ctggtgtcggacgaaatgggcaatatgaataccgaaagctacaaattcatttcccaaaaa
atcagcaccgaaaccggcgaagagccgcgcgccgacatcgtgttcagcatcaaaggcgaa
gaaaaacgcgcttccgcaaccggttccggtccggttgatgcaattttcaaagcgattgaa
agcgtggcgcaaagcggcgcgactttgcagatttattccgtcaatgccgtcacgcaaggt
acggaaagccaaggcgaaaccagcgtccgtctggcacgcggcaaccgcgtcgtcaacggt
cagggcgcggataccgacgttttggttgccaccgccaaagcctacctttccgccttgagc
aaactggaatttagtgccgccaaaccgaaagcgcaaggcagcggtacgatttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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