KEGG   Neisseria meningitidis 8013 (serogroup C): NMV_0458
Entry
NMV_0458          CDS       T01928                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase; D-alanyl-D-alanine-adding enzyme)
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
nmt  Neisseria meningitidis 8013 (serogroup C)
Pathway
nmt00300  Lysine biosynthesis
nmt00550  Peptidoglycan biosynthesis
nmt01100  Metabolic pathways
nmt01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:nmt00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    NMV_0458 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    NMV_0458 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    NMV_0458 (murF)
Enzymes [BR:nmt01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     NMV_0458 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: CAX49392
UniProt: A0A9K2PQF0
Position
434260..435618
AA seq 452 aa
MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRVGDVFFALAGGRFDAHDFVEDVLAA
GAAAVVVSREDCVAMDGALKVDDTLAALQTLAKAWRENVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDGMALIPQEDANMAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGDERAAVVLPVPGRHNVHNAAAAAALSLAAG
LSLNDVAEGLQGFSNIKGRLNVKAGIKGATLIDDTYNANPDSMRAAIDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDPLIQ
VLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq 1359 nt   +upstreamnt  +downstreamnt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
agcaaacccgtgtcgcgcatcgtaaccgacagccgcgacatccgcgtaggcgatgtgttt
ttcgcattggcgggcgggcggtttgacgcgcatgattttgttgaagacgtattggctgcg
ggtgcggcggcggttgtggtttcgcgcgaagattgcgttgcaatggatggcgcgttgaaa
gtcgatgacacgcttgccgcattgcaaacgctggcaaaggcgtggcgcgagaatgtgaac
ccgtttgtgttcggtattaccggctcgggcggtaagacgacggtgaaggaaatgttggct
gcggtattgcgccgccgtttcggcgataatgccgttttggcgacggcaggcaacttcaac
aaccacatcggattgccgttgactttgttgaaattaaacgaaaaacaccgctatgccgtg
attgaaatgggtatgaaccattttggcgaactggcggttttgacacaaatcgccaaaccc
gatgccgcattggtcaacaacgccatgcgcgcccatgtcggctgcggtttcgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatcaaggcttatgttcagacggcatggcg
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgtccacgcggaaaatatcgtgctgaaaccg
ttgtcgtgcgaatttgatttggtgtgcggcgacgaacgcgccgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctgtctttggctgcgggt
ttgagtctgaacgatgtggcggaaggtttgcaaggcttcagcaacatcaaaggccgtctg
aacgtcaaagccggcatcaagggcgcgaccctgattgacgatacctacaacgcgaacccc
gacagcatgagggcagcgattgacgtgttggcgcgtatgcctgcgccgcgcatttttgtg
atgggcgatatgggcgaactgggtgaggacgaagccgccgccatgcacgccgaagtcggc
gcgtacgcccgcgaccaaggcatcgaagcggcttattttgtcggagacaacagcgtcgaa
gcggcggaaaaatttggcgcggacggtttgtggttcgccgccaaagacccgttgattcaa
gtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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