KEGG T05026: 104218186

Nicotiana sylvestris (wood tobacco): 104218186

Entry

104218186         CDS       T05026

Name

(RefSeq) thiamine biosynthetic bifunctional enzyme TH1, chloroplastic isoform X1

K14153

hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]

Organism

nsy Nicotiana sylvestris (wood tobacco)

Pathway

nsy00730

Thiamine metabolism

nsy01100

Metabolic pathways

nsy01240

Biosynthesis of cofactors

Module

nsy_M00897

Thiamine biosynthesis, plants, AIR (+ NAD+) => TMP/thiamine/TPP

nsy_M00899

Thiamine salvage pathway, HMP/HET => TMP

Brite

KEGG Orthology (KO) [BR:nsy00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    104218186
Enzymes [BR:nsy01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     104218186
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     104218186
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     104218186

SSDB

Motif

Pfam:

Phos_pyr_kin TMP-TENI PfkB HK

Other DBs

NCBI-GeneID:

104218186

NCBI-ProteinID:

XP_009766916

UniProt:

A0A1U7VPN3

Position

Unknown

AA seq 550 aa
MAYFCTQVLSTSFFTPKPQIPVLLNPGVACIKSFHQYRFLHIKAMQDDKVSTPTPSDECM
VRVPHVLTVAGSDSGAGAGIQADLKACAARGVYCSTVITAVTAQNTVGVQGVNIVPEDFV
AEQLRSVLSDMHPDVVKTGMLPSIGIVKTLCQSLKEFPVQALVVDPVMVSTSGHTLAGPS
ILDSFREELLPMADIVTPNLKEASALLGGVPLETIADMHYAAKAIHDIGPRNVLVKGGDL
PASLDAVDVFYDGKDFYVFQSSRIMTPNTHGTGCTLASSVAAELAKGSQMLSAVKVAKRY
IEAALSYSKNIAIGGGRQGPVDHLLKLKSNVQRRPFDPCDLFLYAVTDSRMNKRWGRSIV
DAVKAAIEGGATIIQLREKEVETSDFLEAAKACLKICRVHGVPLLINDRIDVALASDADG
VHIGQSDMPAHVARALLGPDKIIGVSCKTPEHALQAWIDGADYIGSGGVYPTTTKENNKT
IGLDGLKTVCLSSKLPVVAIGGIGTSNAQAIMGLGVPNLKGVAVVSALFDRECVLTETRK
LLEVLKESTK

NT seq 1653 nt +upstreamnt +downstreamnt
atggcgtatttctgcactcaggttctatccacttccttctttactcccaaacctcagatt
ccagtgctgttgaatccaggcgtagcttgcatcaaaagctttcatcagtataggtttttg
catattaaggcaatgcaagacgataaggtttccacgcctacgccgtcggatgagtgcatg
gttagagttccgcatgttctgacggttgccggctccgattccggcgccggagccggaatt
caagcggatctcaaggcttgtgctgctcggggagtttattgctccactgtgatcactgct
gttactgctcaaaacaccgtaggggttcagggcgtgaacattgtgccagaggattttgtg
gcggagcagttgaggtcggtgctttctgatatgcatcccgatgtggtgaaaacaggcatg
cttccgtcaattggcatagtgaaaactctctgtcagagtctgaaggaattcccggtacaa
gccttggtggttgaccctgttatggtatccacaagtggacatacgctagctggtccctct
attttggatagttttagggaggagcttcttcccatggctgatatagtgaccccaaatttg
aaagaggcgtccgctttactaggtggtgtgccattggaaacaattgctgacatgcattat
gctgcaaaagcgatacatgacattggtccaagaaatgtacttgtgaaaggaggtgatctc
cctgcttcccttgatgctgtggatgtgttttatgatgggaaggatttctatgtgtttcag
tcttcacgcataatgacaccaaatactcatggaactggctgcactttggcttcttctgtc
gcagctgagctagcaaagggttctcaaatgctttctgctgttaaggtagctaaacgctac
attgaagcagccttgtcttatagtaagaacattgccattggaggtggtcgtcaaggtcct
gtggatcatcttttgaagcttaagagtaatgtgcagcgacgaccttttgatccttgtgat
ctctttctgtatgctgtcactgactccaggatgaacaaaaggtggggtcgttcaatagtt
gatgcggtaaaggctgccatagaaggaggtgccaccattattcagctgagggaaaaggag
gttgaaactagtgattttctggaagcagcaaaagcttgtttaaaaatctgcagagttcat
ggtgttcctctgctgatcaatgacaggattgatgtagctcttgctagtgatgctgatggt
gttcatattgggcaatccgacatgcctgctcatgttgcacgggctcttcttgggcctgac
aaaatcattggtgtatcatgcaaaacaccggagcacgccctgcaagcatggatagatggg
gctgattacattggctctgggggtgtatatccaaccactaccaaagagaacaataagacg
attggtttggatggcctgaaaactgtttgtttgtcatccaaattaccagttgtagccatt
ggcggcataggcacctctaatgctcaggctataatgggactaggggtcccaaacctgaaa
ggcgttgctgttgtatctgctctatttgatagggaatgtgttttgacagagaccagaaag
ctactcgaggtgctcaaggagtcgaccaaatga

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