KEGG   Ornithorhynchus anatinus (platypus): 100080076
Entry
100080076         CDS       T01045                                 
Symbol
KL
Name
(RefSeq) klotho
  KO
K14756  klotho [EC:3.2.1.31]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa00040  Pentose and glucuronate interconversions
oaa00053  Ascorbate and aldarate metabolism
oaa01100  Metabolic pathways
oaa04211  Longevity regulating pathway
oaa04928  Parathyroid hormone synthesis, secretion and action
oaa04961  Endocrine and other factor-regulated calcium reabsorption
Module
oaa_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    100080076 (KL)
   00053 Ascorbate and aldarate metabolism
    100080076 (KL)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    100080076 (KL)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100080076 (KL)
  09149 Aging
   04211 Longevity regulating pathway
    100080076 (KL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:oaa02000]
    100080076 (KL)
   04147 Exosome [BR:oaa04147]
    100080076 (KL)
Enzymes [BR:oaa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.31  beta-glucuronidase
     100080076 (KL)
Transporters [BR:oaa02000]
 Other transporters
  Accessory factors involved in transport [TC:8]
   100080076 (KL)
Exosome [BR:oaa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   100080076 (KL)
SSDB
Motif
Pfam: Glyco_hydro_1
Other DBs
NCBI-GeneID: 100080076
NCBI-ProteinID: XP_028904310
Ensembl: ENSOANG00000015486
Position
20:4078692..4121979
AA seq 1003 aa
MAPGASPLAPLLVLLSLGGPQQPRGAPGDGAWTWGRFSRPRGLEEQRGAQGTFPDGFLWA
VGSAAYQTEGGWRRHGKTPSVWDAFTHRAQGTPTGDVSGDGYHHVGRDAEALRALGVSHY
RFSISWARVLPRGLGGKPNRRGLRYYRRLLRRLGELGVEPVVTLNHWDLPADLQDAYGGW
ASRAVGDRFRDYAELCFRHFGARVKYWITLDNPYVVAWHGYATGRLAPGVRGGRRLGYQV
AHNLLLAHAKVWHLYNTSFRPTQGGQVSIALGSHWINPQNMTESDIRECQKSLDFVLGWF
AKPIFLDGDYPQSMKDNLSSLLPDFTESEKRFIKGTADFFALSFGPTLSFHLLDSQMKFQ
QLESPSLRQLLTWIDLEYNHPQIFIVENGWFVSGSSQRDDAKYLYYLKNFIMETLKAIRY
DAVNVIGYTAWSLVDGFEWHRGYSIRRGLFYVDFLSREKKLLPKSSALFYQKLIEKNGFP
PLPENQPIEGTFPCGFAWGTVDNYIQVDTTLSQFTDPNVYLWDVRESQKLIKVAGVVTPK
REPHCVDFATIRLQISLLQEMHITHFLFSLKWDLILPLGNQSQVNHTMLHYYRCFVSELA
RVNITPVVALWQYTPDHQGLPLPLAKQGAWENPQTIQAFVDYARLCFRDLGPYVKLWLTM
KEPFLQNLTYPAGHNLLKAHALAWHAYDRSFRSSQKGQISIALEANWVEPACPFSQKDRE
VTDRVLEFGIGWLAEPIFGSGDYPQAMRRWLHRQNDFLLPYFTEDEKKLIRGSYDFFALS
HYTTVLMNWEKENPAKYDAYLEVQPMKDITWINSPKMVAVVPWGLRKVLNWIKGKYGDIP
IYITSNGIDDDPHLMQDKLRGYYMQNYINEALKAYILDDINLCGYFFYSFNDRTSPSYGL
YRYAANQYEAKPSMRHYRKIIDSNGFPGPGTLGRFCPEEPDLCTECSFFQTRKSLLAFTS
FLLFACIVTISLIIYYSRATPTPQKLNPPGGGGKDKRLSGILP
NT seq 3012 nt   +upstreamnt  +downstreamnt
atggcccccggggcttcgcctctcgcccctctcttggtgctgctgagcctgggggggccc
cagcagcctcggggggcccccggggacggcgcctggacgtgggggcgtttctcgcggcct
cggggcctggaggagcagcgtggagcgcagggtaccttccccgacggcttcctctgggcg
gtgggcagtgccgcctaccagacggagggcggctggaggcggcacggcaagaccccctcg
gtgtgggacgccttcacccaccgggcccagggcacccccacgggggacgtgtccggggac
ggctaccaccacgtggggcgggacgccgaggccctgcgggccctgggggtcagccactac
cgcttctccatctcctgggcccgcgtcctgccccggggtttgggcgggaaacccaaccgc
cggggcctgcgttattaccggcgcctgctgcggaggctgggcgagctgggcgtggagccg
gtggtcaccctcaaccactgggacctgcccgccgacctgcaggacgcctacggaggctgg
gccagccgggccgtgggggacaggttccgcgactacgccgagctctgcttccgacacttc
ggggcccgggtcaagtactggatcacgctggacaacccctacgtggtggcctggcacggc
tacgccaccggacggctggcccccggggtccgaggaggtcgccggctcggctaccaggtg
gcccacaacctgctgctggctcatgccaaagtctggcacctctacaatacttcatttcgt
cctactcaaggaggccaagtgtccattgcacttggctcccattggataaatcctcaaaac
atgaccgagagtgacatcagagagtgtcaaaagtcccttgactttgtgctgggctggttt
gctaagcccatatttctagatggcgactacccccaaagcatgaaggataacctctcatct
cttctgcctgatttcactgaatccgagaaaaggttcatcaagggcacggctgactttttt
gctctttcctttggaccaactctgagttttcacctcttggactctcaaatgaagttccag
cagttggaatccccaagcctgaggcagctccttacctggatagaccttgaatataaccac
ccccagatattcattgtggagaatggctggttcgtctctggcagttcccagagagatgat
gccaagtatttgtattatctcaaaaatttcattatggaaaccttaaaagccatcagatat
gacgcggtcaatgtcattgggtacactgcgtggtccctcgtggatggcttcgaatggcac
agaggatacagcattaggcgtggactgttctacgtcgatttcctgagccgcgagaagaag
ttgctgcccaagtcttcagccttgttctaccagaagttgatcgagaaaaatggcttcccc
cccttacctgaaaatcagcccatcgaggggacgtttccctgcggctttgcctgggggact
gttgacaactacattcaagtggacacgactctttcccagtttactgacccaaacgtatac
ctgtgggatgtccgcgagagccagaaacttattaaagtggccggggttgttaccccgaag
cgggagccgcactgtgtggactttgctaccatccgactccagatctccttacttcaggaa
atgcacataactcattttctcttctcgttgaagtgggacctgattctccccttgggcaac
cagtctcaagtcaaccatacgatgttgcactattaccggtgttttgttagcgaactggct
cgggtcaacatcacgccggtggttgctctgtggcagtacaccccggatcaccaaggactc
cccctccccttagccaagcagggggcctgggagaacccccagaccatccaggccttcgtg
gactacgcccggctctgttttagagacctcggcccctacgtcaaattgtggctcacgatg
aaggaacctttcctgcagaatctgacctaccccgccgggcataacctgttgaaagcccac
gcgttggcctggcacgcgtacgacagatcatttagaagttcccagaagggccagatctcc
atagccctggaagccaactgggtggagccggcttgccctttctcccagaaagacagagag
gtgacagaccgcgtcctggaatttggcatcggttggctcgccgaacccatcttcggcagc
ggtgactacccccaggcgatgaggaggtggctgcaccggcaaaacgactttctcttgcct
tacttcacggaagatgagaagaagctgatccggggatcttacgacttcttcgccttgagc
cactacacgaccgtcctgatgaactgggaaaaagagaatccggccaagtacgatgcttac
ctagaagtgcagcccatgaaagacatcacctggataaactcccccaaaatggtggccgtg
gtgccctgggggctgcgcaaggtccttaactggattaaaggcaaatacggcgacatcccc
atctacatcacttccaatggcattgatgatgatcctcatctgatgcaggataagctgagg
gggtattatatgcagaattacatcaatgaagccttaaaagcctacatattggatgatatc
aacctctgtggctactttttttattcgtttaatgaccgaacctctccctcgtacggactc
taccgttacgccgctaatcaatatgaggcgaagccatccatgagacactatcgtaaaatt
attgacagcaacggctttccaggccccgggactctgggaaggttctgcccggaagagcca
gatctgtgcaccgaatgcagcttcttccagacccgaaagtccctgctggccttcacctca
ttcctcctttttgcttgtatcgttaccatttctctgatcatttactactccagggccaca
ccgacaccccagaaactgaaccccccggggggtggagggaaagacaaacgcctgagcggg
atactgccctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (1)   
   Pfam (1)   
All databases (47)   

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