KEGG   Ornithorhynchus anatinus (platypus): 100081728
Entry
100081728         CDS       T01045                                 
Symbol
MLKL
Name
(RefSeq) mixed lineage kinase domain-like protein
  KO
K08849  mixed lineage kinase domain-like [EC:2.7.11.1]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04217  Necroptosis
oaa04623  Cytosolic DNA-sensing pathway
oaa04668  TNF signaling pathway
oaa05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    100081728 (MLKL)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100081728 (MLKL)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    100081728 (MLKL)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100081728 (MLKL)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oaa01001]
    100081728 (MLKL)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100081728 (MLKL)
Protein kinases [BR:oaa01001]
 Serine/threonine kinases: TKL group
  Other
   100081728 (MLKL)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase RPW8 EST1_DNA_bind TssC Saf4_Yju2 COG6_N
Other DBs
NCBI-GeneID: 100081728
NCBI-ProteinID: XP_007655108
Position
11:complement(36665084..36682954)
AA seq 502 aa
MEILGHILDLAQKIYDRCETVKCCQKQCRRLGDRILILKTPLERLRDLQEEDWSGELEYI
LNKLQGALEKAKSLIEQFSQKDIFQKFLSISSTEEDFALVNDHMSDAAEGLSLLLQTEQR
QLIRETFRRETRQRQDRRDAKEDRAHWEELLKGNKEIKAEVQKVQNSMIHVESSMENLAT
DMKKILRLAEQSQQSSSPAAQEKIKEIKIEQLIKTPWVLRMENKYHMLYIGEYYKSPVSI
KVFKDTQGTSPRAIRKIFNKEIETMKKFEYPNILRIYGICIDERGPQPRFLLVMEYCELG
TLGELLEAKPDLTWEERVFLALGAARGLYRLHHSEEKTKLHGCITSAKFLVAKGYEVKLA
GLELSQTESSISRNSKGEKAKETHASAYVSPQSLENLNHEYDIPAEIYSFGIVLWEIATG
KIPFQGCSIQEIFQQVYKERYQEPVRGDCPQALKEITDQCRAYHPSERPSAEDIVDKLSA
LCDELNGVKSGLKKSKTQEASS
NT seq 1509 nt   +upstreamnt  +downstreamnt
atggagatcttgggacacatcttggatttagctcagaagatctacgatcggtgtgagact
gtgaaatgctgtcagaaacaatgtaggcgcctcggtgaccggatcctcatcctgaaaacc
cccttggagaggcttcgggacctacaggaagaagactggtccggcgagctggaatacatc
ctgaacaagctacagggggctctagagaaagccaaatcactgatagagcaattcagccaa
aaagacatattccaaaagttcctgagcatcagtagcaccgaggaagatttcgccctggtg
aacgaccacatgagcgatgctgccgagggcctctccctcctgctccagacagagcagcgg
cagcttatccgggagaccttccggagggagacccgccagcggcaagatcgccgggatgcc
aaggaagacagggcccactgggaagaactgcttaaaggcaacaaagaaatcaaagctgaa
gtgcagaaggtccagaattctatgatacacgtggaaagcagcatggaaaatttggctact
gatatgaagaaaattcttagattagcagaacaatctcagcagtcatccagtcctgctgca
caagagaaaattaaggagattaagatagagcagcttataaagaccccttgggttctgagg
atggaaaacaaatatcacatgctctacattggagaatattacaagtccccagtgtccatc
aaagtcttcaaagacactcagggcaccagtccaagagcaataaggaagattttcaacaaa
gagattgaaaccatgaagaaattcgagtatccaaatatcttgcgaatatatgggatatgc
attgatgagagaggacctcagcctcgcttcttgctggtcatggaatattgcgaacttggg
actctgggcgaactgctggaagccaaaccggacctcacctgggaggagcgtgtgttcctg
gccctgggagcagccaggggcctgtacaggttgcaccattcagaggagaagactaaattg
cacggctgcatcaccagtgccaagttcctcgtggctaaaggctatgaggtgaaactggca
ggattagaactgagccaaacggagtcttccatcagtcggaactcgaaaggggaaaaagca
aaggaaacccatgcttcagcgtatgtttctcctcagagcctggaaaatctaaaccacgag
tacgacatccctgctgaaatctacagctttgggatcgtcctctgggaaatcgccactggg
aagatcccattccagggttgcagcatccaagagatcttccagcaggtgtataaggagcgt
taccaagagcctgtgaggggggactgcccccaggccctgaaggagatcactgaccagtgc
cgggcctaccatccctctgaacgcccttcggccgaagacatcgtggacaagctgtctgct
ctctgtgatgaactaaatggcgtaaaatcaggtctgaagaagagcaagacccaagaagct
tcatcataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (30)   

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