KEGG   Ornithorhynchus anatinus (platypus): 100092226
Entry
100092226         CDS       T01045                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform X1
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa03015  mRNA surveillance pathway
oaa04022  cGMP-PKG signaling pathway
oaa04024  cAMP signaling pathway
oaa04114  Oocyte meiosis
oaa04218  Cellular senescence
oaa04261  Adrenergic signaling in cardiomyocytes
oaa04270  Vascular smooth muscle contraction
oaa04390  Hippo signaling pathway
oaa04510  Focal adhesion
oaa04611  Platelet activation
oaa04720  Long-term potentiation
oaa04728  Dopaminergic synapse
oaa04750  Inflammatory mediator regulation of TRP channels
oaa04810  Regulation of actin cytoskeleton
oaa04910  Insulin signaling pathway
oaa04921  Oxytocin signaling pathway
oaa04931  Insulin resistance
oaa05031  Amphetamine addiction
oaa05034  Alcoholism
oaa05168  Herpes simplex virus 1 infection
oaa05205  Proteoglycans in cancer
oaa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    100092226 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    100092226 (PPP1CA)
   04024 cAMP signaling pathway
    100092226 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    100092226 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100092226 (PPP1CA)
   04218 Cellular senescence
    100092226 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100092226 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100092226 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100092226 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100092226 (PPP1CA)
   04921 Oxytocin signaling pathway
    100092226 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100092226 (PPP1CA)
   04270 Vascular smooth muscle contraction
    100092226 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    100092226 (PPP1CA)
   04720 Long-term potentiation
    100092226 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100092226 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100092226 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    100092226 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100092226 (PPP1CA)
   05034 Alcoholism
    100092226 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100092226 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100092226 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:oaa01009]
    100092226 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:oaa03021]
    100092226 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:oaa03019]
    100092226 (PPP1CA)
   03041 Spliceosome [BR:oaa03041]
    100092226 (PPP1CA)
Enzymes [BR:oaa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100092226 (PPP1CA)
Protein phosphatases and associated proteins [BR:oaa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100092226 (PPP1CA)
Transcription machinery [BR:oaa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100092226 (PPP1CA)
Messenger RNA biogenesis [BR:oaa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     100092226 (PPP1CA)
Spliceosome [BR:oaa03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100092226 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 100092226
NCBI-ProteinID: XP_028916312
Ensembl: ENSOANG00000011413
Position
3:615953..620493
AA seq 330 aa
MADSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLTPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atggccgacagcgagaagctcaacctcgactccatcatcggacgcctcctggaagtacaa
ggctcccgcccgggcaagaatgtgcagctgacggagaacgagatccggggcctgtgcctc
aaatcccgggagatcttcctgagccagcccatcctgctggaactggaggcccccctcaag
atctgcggcgatatccacggccagtactacgacctgctgcggctctttgagtacgggggc
ttccctcccgaaagcaactacctcttcctgggagactacgtggaccggggcaagcagtcg
ctggagaccatctgcctgctcctggcctacaagatcaagtacccggagaacttcttcctg
ctgcggggcaaccacgagtgcgccagcatcaaccgcatctacggcttctatgacgagtgc
aaacgacgttacaacatcaagctctggaaaaccttcaccgactgcttcaactgccttccc
atcgcggccatcgtagacgagaagatcttctgctgccatggggggctgtccccggacctg
cagtcgatggagcagatccggcgcatcatgcggcccacggacgtcccggaccagggcctg
ctctgcgacctgctgtggtccgacccggacaaggacgtgcagggctggggcgagaacgac
cgcggtgtctccttcaccttcggcgctgaggtcgtggccaagttcctgcacaagcacgac
ttggacctcatctgccgtgcacaccaggtggtggaagacggctacgagttctttgccaag
aggcagctggtgacgctcttctcggccccgaactactgtggcgagttcgacaatgcgggt
gccatgatgagcgtggacgagacgctcatgtgctccttccagatcctcaaaccagccgac
aagaacaaggggaagtacggccagttcagcggcctgactcccgggggccgccccatcacc
ccgccccgcaactctgccaaagccaaaaagtag

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Ontology (6)   
   KEGG BRITE (6)   
Pathway (22)   
   KEGG PATHWAY (22)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (2)   
   Pfam (2)   
All databases (69)   

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