KEGG   Ornithorhynchus anatinus (platypus): 114817945
Entry
114817945         CDS       T01045                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa00480  Glutathione metabolism
oaa00980  Metabolism of xenobiotics by cytochrome P450
oaa00982  Drug metabolism - cytochrome P450
oaa00983  Drug metabolism - other enzymes
oaa01100  Metabolic pathways
oaa01524  Platinum drug resistance
oaa05200  Pathways in cancer
oaa05204  Chemical carcinogenesis - DNA adducts
oaa05207  Chemical carcinogenesis - receptor activation
oaa05208  Chemical carcinogenesis - reactive oxygen species
oaa05225  Hepatocellular carcinoma
oaa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    114817945 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    114817945 (MGST1)
   00982 Drug metabolism - cytochrome P450
    114817945 (MGST1)
   00983 Drug metabolism - other enzymes
    114817945 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114817945 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    114817945 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    114817945 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    114817945 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    114817945 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    114817945 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    114817945 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:oaa02000]
    114817945 (MGST1)
Enzymes [BR:oaa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     114817945 (MGST1)
Transporters [BR:oaa02000]
 Other transporters
  Pores ion channels [TC:1]
   114817945 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 114817945
NCBI-ProteinID: XP_028938485
Ensembl: ENSOANG00000039546
Position
2:167166699..167190629
AA seq 152 aa
MEGLMDNEILRAFASYATIVLSKMMLMSTITAYFRITRKAFANPEDAASLGKGENPKKFV
RTDEAVERVRRAHLNDLENVVPFLGVGLLYALSGPDLGAALLHFRLFAFSRLYHGVAYLV
PLPQPNRGLAFFLGYGVTLSMACGLLRRHLYL
NT seq 459 nt   +upstreamnt  +downstreamnt
atggaggggctaatggacaacgagatcctgagggcctttgcttcctacgcgaccatcgtg
ctgtccaaaatgatgctcatgagcaccatcaccgcctacttcagaatcaccaggaaggct
ttcgccaacccggaagacgcagcgtccctggggaagggagagaacccgaagaagtttgtc
cggacggatgaggccgtggagagagtacgcagggctcacctgaacgacttggagaacgtg
gtgccgttcctgggcgtggggctgctgtacgccctgagcgggccggacctgggggccgcc
ctgctgcacttccgcctcttcgccttctcccgcctctaccacggcgtggcctacctcgtc
cccctgccccagcccaaccgcggcctcgccttcttcctcggctacggcgtcaccctctcc
atggcctgcggtctcctcagacgccacctctacctctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (91)   

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