KEGG   Ovis aries (sheep): 101107354
Entry
101107354         CDS       T03117                                 
Symbol
VAV1
Name
(RefSeq) proto-oncogene vav
  KO
K05730  guanine nucleotide exchange factor VAV
Organism
oas  Ovis aries (sheep)
Pathway
oas04015  Rap1 signaling pathway
oas04024  cAMP signaling pathway
oas04062  Chemokine signaling pathway
oas04510  Focal adhesion
oas04650  Natural killer cell mediated cytotoxicity
oas04660  T cell receptor signaling pathway
oas04662  B cell receptor signaling pathway
oas04664  Fc epsilon RI signaling pathway
oas04666  Fc gamma R-mediated phagocytosis
oas04670  Leukocyte transendothelial migration
oas04810  Regulation of actin cytoskeleton
oas05135  Yersinia infection
oas05205  Proteoglycans in cancer
oas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101107354 (VAV1)
   04024 cAMP signaling pathway
    101107354 (VAV1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101107354 (VAV1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101107354 (VAV1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    101107354 (VAV1)
   04660 T cell receptor signaling pathway
    101107354 (VAV1)
   04662 B cell receptor signaling pathway
    101107354 (VAV1)
   04664 Fc epsilon RI signaling pathway
    101107354 (VAV1)
   04666 Fc gamma R-mediated phagocytosis
    101107354 (VAV1)
   04670 Leukocyte transendothelial migration
    101107354 (VAV1)
   04062 Chemokine signaling pathway
    101107354 (VAV1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101107354 (VAV1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101107354 (VAV1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101107354 (VAV1)
SSDB
Motif
Pfam: RhoGEF SH3_1 SH3_2 CAMSAP_CH CH SH2 SH3_9 C1_1 PH CDC24 C1_2 LZ3wCH
Other DBs
NCBI-GeneID: 101107354
NCBI-ProteinID: XP_027825564
EnsemblRapid: ENSOARG00020015323
Position
5:complement(15406620..15472087)
AA seq 844 aa
MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREV
NLRPQMSQFLCLKNIRTFLSTCYEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPI
AQNKGIMPFPTEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEVYEDLMRSE
PVPMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLNHQDIEIIFINIE
DLLHVHIHFLKEMKEALANPSAATLYQVFIKYKERFLIYGRYCSQVESASKHLDRVATAR
EDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDAMEKDNLRLALD
AMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMD
RYAFLLDKALLICKRRGDSYDLKDFVNLHSFQIRDDSSGERDNKKWTHMFLLIEDQGAQG
YELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEDTASCKACQMLLRGTFY
QGYRCQRCRAPAHKECLGRVPPCGRHGQDYSGTMKKDKPHRRAQDKKRNELGLPKMEVCQ
EYYGLPPPPGAIGPFLRLSLGDIVELTKAEAEQNWWEGRNTSTNEVGWFPCNRVKPYVHG
PPQDLSVHLWYAGPMERAGAESILTNRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIM
TAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPERRAISKPPAGST
KYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPSNYVEEDY
SEYC
NT seq 2535 nt   +upstreamnt  +downstreamnt
atggagctgtggcgccagtgcacccactggctcatccagtgccgggtgctaccgcccagc
caccgtgtgacctgggatggagcccaggtgtgcgagctggcgcaggccctccgggatggc
gtccttctgtgccagctgctcaacaacctgctgccccacgctatcaacctgcgggaagtc
aacctgcgtccccagatgtcccagttcctctgccttaagaatatccgcactttcctgtct
acctgctatgagaagtttggcctcaagaggagtgaactctttgaggccttcgacctcttc
gatgtgcaggattttggcaaggtcatctacaccctatccgctctgtcctggaccccgatt
gcccagaacaaggggatcatgcccttccccactgaggagagtgtgggtgatgaagacatc
tacagtggactgtccgaccagatcgacgacacggtggaggaggatgaggacctgtacgac
tgcgtggagaacgaggaggcagagggcgatgaggtctacgaggacctcatgcgctcggag
ccggtacccatgccgcccaagatgacagagtatgacaagcggtgctgctgtctgcgggag
atccagcagacggaggagaagtatacggacacgctgggctccatccaacagcattttatg
aagcccttgcagcggttccttaaccaccaagacatcgagattatcttcatcaacattgag
gacctgcttcatgtgcacatccatttcctaaaggagatgaaggaagccctggccaacccc
agtgcagccaccctctaccaggtcttcatcaaatacaaggagaggttcctcatctacggc
cgctactgcagccaggtggagtcggccagcaagcacctggaccgcgtggccacagcccgg
gaggatgtacaaatgaagctggaagaatgttctcagcgtgccaacaacgggaggttcacc
ttaagggacctgttgatggtccccatgcagcgagtgctcaaatatcacctcctgctccag
gagctggtgaagcacacacaggatgcgatggagaaggacaacctgcggctggccctagat
gccatgagggacctggcacagtgcgtaaacgaggtcaagcgggacaatgagacgctgcgg
cagattaccaacttccaactgtccatcgagaacctggaccagtctctagcccactatggc
cgacccaagatcgatggtgagctgaagataacttcggtggagaggcgctccaagatggac
aggtatgccttcctgcttgacaaagctctgctcatctgtaagcgccgaggggactcctat
gacctcaaggactttgtgaacctgcacagcttccagattcgagatgactcctccggagag
agggacaacaagaagtggactcacatgttcctcctgattgaggaccaaggtgctcagggc
tatgagctgttcttcaagacacgagaactaaagaagaagtggatggagcagttcgagatg
gccatctccaacatctaccctgagaacgccactgccaatggtcatgacttccagatgttt
tcctttgaggacaccgcatcctgcaaggcttgccagatgctgctgagaggcactttctat
caggggtaccgctgtcaacggtgccgagcacctgcacacaaggagtgtcttgggagggtc
cctccatgtggtcgacatggacaagattattcaggaactatgaagaaggataagccacat
cggcgggctcaagacaaaaagaggaatgagctaggcctgcccaagatggaggtgtgccag
gaatactatgggctgcccccaccccctggagccattggaccttttctacgcctcagcctg
ggagacatcgtggagctcactaaggctgaagccgaacagaactggtgggagggaaggaat
acgtctaccaatgaagtcggctggtttccctgcaatagggtcaagccctacgtgcatggt
cccccccaggacctgtctgttcatctctggtacgctggccccatggagcgagccggggcg
gaaagcattcttaccaaccgctcggatgggacgttcttggtgcggcagagggtgaaggat
gctgcagaatttgccatcagcattaagtataatgttgaagtcaagcatattaaaatcatg
acagcagaaggactgtaccggattacagaaaagaaagctttcagggggcttacggagctg
gtggaattctaccagcagaactctctgaaggattgcttcaagtcactggacaccaccctg
cagttccccttcaaggagcctgagaggagagccattagcaaaccaccagccgggagcacc
aagtactttggcacggccaaagcccgctatgacttctgcgcccgggaccgatcagagctg
tccctcaaagagggcgacattatcaagatccttaacaagaaggggcagcagggctggtgg
cgaggggagatctacggccgggttggctggttcccctccaactatgtggaagaggactat
tctgagtactgctga

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (12)   
   Pfam (12)   
All databases (35)   

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