KEGG   Ovis aries (sheep): 101115372Help
Entry
101115372         CDS       T03117                                 

Gene name
PLA2G4B
Definition
(RefSeq) cytosolic phospholipase A2 beta isoform X2
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
oas  Ovis aries (sheep)
Pathway
oas00564  Glycerophospholipid metabolism
oas00565  Ether lipid metabolism
oas00590  Arachidonic acid metabolism
oas00591  Linoleic acid metabolism
oas00592  alpha-Linolenic acid metabolism
oas01100  Metabolic pathways
oas04010  MAPK signaling pathway
oas04014  Ras signaling pathway
oas04072  Phospholipase D signaling pathway
oas04217  Necroptosis
oas04270  Vascular smooth muscle contraction
oas04370  VEGF signaling pathway
oas04611  Platelet activation
oas04664  Fc epsilon RI signaling pathway
oas04666  Fc gamma R-mediated phagocytosis
oas04724  Glutamatergic synapse
oas04726  Serotonergic synapse
oas04730  Long-term depression
oas04750  Inflammatory mediator regulation of TRP channels
oas04912  GnRH signaling pathway
oas04913  Ovarian steroidogenesis
oas04921  Oxytocin signaling pathway
oas05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    101115372 (PLA2G4B)
   00565 Ether lipid metabolism
    101115372 (PLA2G4B)
   00590 Arachidonic acid metabolism
    101115372 (PLA2G4B)
   00591 Linoleic acid metabolism
    101115372 (PLA2G4B)
   00592 alpha-Linolenic acid metabolism
    101115372 (PLA2G4B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101115372 (PLA2G4B)
   04010 MAPK signaling pathway
    101115372 (PLA2G4B)
   04370 VEGF signaling pathway
    101115372 (PLA2G4B)
   04072 Phospholipase D signaling pathway
    101115372 (PLA2G4B)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    101115372 (PLA2G4B)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101115372 (PLA2G4B)
   04664 Fc epsilon RI signaling pathway
    101115372 (PLA2G4B)
   04666 Fc gamma R-mediated phagocytosis
    101115372 (PLA2G4B)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101115372 (PLA2G4B)
   04913 Ovarian steroidogenesis
    101115372 (PLA2G4B)
   04921 Oxytocin signaling pathway
    101115372 (PLA2G4B)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101115372 (PLA2G4B)
  09156 Nervous system
   04724 Glutamatergic synapse
    101115372 (PLA2G4B)
   04726 Serotonergic synapse
    101115372 (PLA2G4B)
   04730 Long-term depression
    101115372 (PLA2G4B)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101115372 (PLA2G4B)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    101115372 (PLA2G4B)
Enzymes [BR:oas01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     101115372 (PLA2G4B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B cPLA2_C2 C2 BMF
Motif
Other DBs
NCBI-GeneID: 101115372
NCBI-ProteinID: XP_004010521
Ensembl: ENSOARG00000020432
UniProt: W5QGU7
Position
7
AA seq 784 aa AA seqDB search
MALAKVPGTCLLTIRVLQAHGLPSKDLVTSSDCYVTLWLPTASSHQLQTRTVKNCRNPVW
NQSFHFRIHSQIKNIVHLRVFDQDLLTTDDPVLSVLFDVGTLRAGETRRKSFSLSPQGEE
RLEVEFRLQNLTDGAEYLFSNGILVARELSCLHVRLEKAGDFQESEGRVQLVVPGSCEGP
QEAFVGAGSFRFHWPACWEQELSIHLQDAPQEQLKVPLRALPSGQVVRLVFPTSQEPLMK
VELKNEEGSRELAVRLGCGPCAEEQAFLSRRKQVVAKALQQALQLDGDLREEEIPVVAVM
ATGGGIRAMTSLYGQLAGLKALGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPIE
SLKTQVTKSKLGVLAPRQLLRYQQELAERARLGHPTCFTNLWALVNEALLHDEPHDYKLS
DQREALSRGQNPLPIYCALNTKEQNLTTFEFGEWCEFSPYEVGFPKYGAFIPPELFGSEF
FMGRLTKQLPESRICFLEGIWSNLYAANLQDSLYWSSEPSQFWDRWAQARASLDKEQVPL
LKIEEPPTVAGSIAEVFTDLLTRRPLAQATHNFLRGFSFHKDYFQHPHFSAWKATKLDGL
PNELTPAEPYLCLLDVGYLVNTSCPPLLPPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE
QGIPFPPISPSPEEQCQPQECHLFSDPARPDIPAVLHFPLVNASFRDHSAPGVRRTAEEQ
AAGEVNLSESDSPYHYSKVTYSLEDVDKLLRLTQYNICNNQERLLEALREAMQRRRQRTQ
RRPE
NT seq 2355 nt NT seq  +upstreamnt  +downstreamnt
atggctctggcaaaggtgcctgggacctgcttactcaccattcgtgtcctgcaggcccat
ggcctgccctccaaggaccttgtgacctcctctgactgctacgtgaccctgtggctgccc
acggcctccagccaccagctgcagacgcgcacagtcaagaactgcagaaaccctgtctgg
aatcagagctttcacttccgaatccatagccagatcaagaacattgtgcatctcagagtc
tttgaccaagaccttctgaccacggatgaccctgtgttgtcagtgctgtttgacgtgggg
accttgcgggctggggagacccggcgcaagagcttctcgctgagccctcagggtgaggaa
cgcctggaagttgaatttcggctgcaaaatctgactgatggtgctgagtacctcttcagc
aatggcatcctagtggcccgggagctctcctgcttgcatgttcgactggagaaggcaggg
gactttcaggagtcggagggcagagttcagcttgtggttcctgggtcctgtgagggtcca
caggaagccttcgtgggtgccggctccttccgcttccattggccagcctgctgggagcag
gagctgagtattcacctgcaggatgccccccaagagcagctgaaggtgcccctgagggct
ctgccctctggccaagtggtgcgactcgtcttccctacgtcccaggagcccctgatgaaa
gtggagctgaaaaatgaagaaggatccagggaactggctgtgcggctgggctgcgggccc
tgtgctgaggagcaggccttcctgagcaggaggaagcaggtggtagccaaggccctgcag
caggccctgcagctggatggagacctgcgggaagaggagattccagtggttgctgttatg
gccactggtggtggtatccgggccatgacctcactgtatggacagctggctggcctaaag
gcgcttggcctcttggattgtgtctcctacatcacaggggcctcgggctccacctgggct
ttggccaacctctacgaggatccagagtggtctcagaaggacctggcagggcccatcgag
tcactgaagacccaggtgaccaagagcaagctgggtgtgctagcccccaggcagctactg
cggtaccagcaggagctggctgagcgtgcccgcctgggccacccgacctgcttcaccaac
ctgtgggccctcgtcaacgaggcgctgctacatgacgagcctcatgactacaagctctca
gaccagcgggaggccctgagtcgaggccagaaccccctgcccatttactgtgctctcaac
accaaggaacagaatctgaccacctttgaatttggggagtggtgtgagttctccccctac
gaggtcggctttcccaagtacggcgccttcatcccccccgagctcttcggctctgagttc
ttcatggggcgcctgacaaaacagcttcctgagtcccgtatctgtttcctggaaggtatc
tggagcaacctgtacgcagccaacctccaggacagcctgtactggtcatccgagcccagc
cagttctgggaccgctgggcacaagctcgagccagcctggacaaggagcaggtccccctt
ctgaagatagaagagcctcccacggtggccggcagcatagcggaggttttcaccgacctt
ctgacgcggcgtccacttgcccaggccacccacaacttcctacgtggcttctccttccac
aaggactatttccagcaccctcacttttctgcctggaaagctaccaaactggacggcctt
cccaacgagctgacacctgcagagccctacctttgcttgctggatgttgggtaccttgtc
aataccagctgcccacccctcctgccgcccacacgggacgtggacctcatcctgtcgcta
gattacaatctccatggagccttccagcagctgcagcttctgggtcggttctgccaagag
cagggcatcccgttcccgcccatctcgcccagccccgaggagcagtgccagccccaagag
tgccaccttttctcggaccccgcccgccctgacatccctgccgtgctgcacttccctctg
gtcaatgcctccttcagggaccactctgcccccggggtccgacggacagcagaggagcag
gcggctggggaagtgaacctatctgaatccgactccccctaccactactcgaaggtgacc
tacagcctggaggacgtggacaagctgctccgcctgacgcagtacaacatttgcaacaac
caggagcggctgctggaggccctgcgtgaggccatgcagaggcggaggcagcgcacgcag
cgccggcctgagtga

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