KEGG   Ovis aries (sheep): 101116403Help
Entry
101116403         CDS       T03117                                 

Gene name
PLA2G4F
Definition
(RefSeq) cytosolic phospholipase A2 zeta isoform X1
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
oas  Ovis aries (sheep)
Pathway
oas00564  Glycerophospholipid metabolism
oas00565  Ether lipid metabolism
oas00590  Arachidonic acid metabolism
oas00591  Linoleic acid metabolism
oas00592  alpha-Linolenic acid metabolism
oas01100  Metabolic pathways
oas04010  MAPK signaling pathway
oas04014  Ras signaling pathway
oas04072  Phospholipase D signaling pathway
oas04217  Necroptosis
oas04270  Vascular smooth muscle contraction
oas04370  VEGF signaling pathway
oas04611  Platelet activation
oas04664  Fc epsilon RI signaling pathway
oas04666  Fc gamma R-mediated phagocytosis
oas04724  Glutamatergic synapse
oas04726  Serotonergic synapse
oas04730  Long-term depression
oas04750  Inflammatory mediator regulation of TRP channels
oas04912  GnRH signaling pathway
oas04913  Ovarian steroidogenesis
oas04921  Oxytocin signaling pathway
oas05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    101116403 (PLA2G4F)
   00565 Ether lipid metabolism
    101116403 (PLA2G4F)
   00590 Arachidonic acid metabolism
    101116403 (PLA2G4F)
   00591 Linoleic acid metabolism
    101116403 (PLA2G4F)
   00592 alpha-Linolenic acid metabolism
    101116403 (PLA2G4F)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101116403 (PLA2G4F)
   04010 MAPK signaling pathway
    101116403 (PLA2G4F)
   04370 VEGF signaling pathway
    101116403 (PLA2G4F)
   04072 Phospholipase D signaling pathway
    101116403 (PLA2G4F)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    101116403 (PLA2G4F)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101116403 (PLA2G4F)
   04664 Fc epsilon RI signaling pathway
    101116403 (PLA2G4F)
   04666 Fc gamma R-mediated phagocytosis
    101116403 (PLA2G4F)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101116403 (PLA2G4F)
   04913 Ovarian steroidogenesis
    101116403 (PLA2G4F)
   04921 Oxytocin signaling pathway
    101116403 (PLA2G4F)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101116403 (PLA2G4F)
  09156 Nervous system
   04724 Glutamatergic synapse
    101116403 (PLA2G4F)
   04726 Serotonergic synapse
    101116403 (PLA2G4F)
   04730 Long-term depression
    101116403 (PLA2G4F)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101116403 (PLA2G4F)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    101116403 (PLA2G4F)
Enzymes [BR:oas01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     101116403 (PLA2G4F)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B cPLA2_C2 C2
Motif
Other DBs
NCBI-GeneID: 101116403
NCBI-ProteinID: XP_004010525
Ensembl: ENSOARG00000020480
Position
7
AA seq 845 aa AA seqDB search
MLWALWPRWLTSKGLPLLGAVQLQKREKRGPQWKQWRRETHPFYDLQVKVLRAKNIQGTD
LLSKADCYVQLWLPSASPSPARTRVVANCSDPEWNETFHYRIHGAVKNVLELTLYDKDIL
DNDQLALLLFDLRSLKPGLPHRHTFPISQQESHELQVEFVLEKSQVPAPEVITNGVLVAQ
PCMRIQGTLRGDGTAPHLEHGPRQIQLAVPGAYEKPQLLPLQPPTETGVPAMFTFHVNPV
LSSRLEVGLGKKLMVQGDPRVKEETQTSKPGILLSSLALGQEQQCVVALGEGKEVAISVK
AEMSSGDLDLRLGFDLCDGEKEFLEKRKRLVSKAFQQALGLSHAPDSSQVPVVAVLGSGG
GTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYKDPAWSQVALQGPIERAQA
RVCSSKMGAMSTERLHYYAQELGIRESSGHSTSLVDLWGLLIEYFLYQEENPAKLSDQKE
AVSQGQNPYPIYASVNVRSNVSGEDFAEWCEFTPHEVGFPKYGAYVPTELFGSDFFMGRL
LQLRPESRICYLQGMWGSAFAASLDEIFLKTSGRGLSFLDWRKDSVNITDDCQDLQLHKP
GRLRTRLFTPQGPFYQALLDICTSRLTSAKNSNFTRGLYLHEDYASGREFVAWKDLHPDA
FPNQLTPMRDCLYLVDGGFAINSPFPLSLQPQRAVDLILSFDYSLDAPFEVLQMTEKYCL
DRGISFPRIEVSPEDIKEPHECYLFAKAEDPSSPIILHFPLVNRTFRTHLAPGVERKTAE
EKAGGDFVINGPDTPYGMMNFTYEPQEFEQLVALSRYNVLNNVETVRKALQLALDRRQTG
DRTGG
NT seq 2538 nt NT seq  +upstreamnt  +downstreamnt
atgctctgggcgctctggcccaggtggctgacaagcaaggggctgcccctcctgggtgcg
gtgcagctacagaagcgagagaagaggggacctcagtggaagcagtggcggcgagagacc
caccccttctatgacctccaggtgaaggtgctgagggccaaaaatatccagggcacagac
ctgctgtccaaagctgactgctatgtgcaactgtggctgccctcagcatcccccagcccc
gcccggaccagggtggtggccaactgcagtgaccccgagtggaacgagaccttccactac
cggatccatggtgccgtgaagaatgtcctggagctcaccctctatgacaaggacatcctg
gacaatgaccagctcgctctgctgctttttgatctgaggagcctcaagccaggcctacca
cacagacacaccttccccatcagccagcaggagtcacacgagctgcaggtggaatttgtt
ttggagaagagccaggtgcccgcacctgaagtcatcactaatggggtcctggtggctcag
ccatgtatgagaatccagggcaccctcaggggcgatgggacagccccacatctagagcac
ggtcctaggcagattcagctggcagtgcccggagcctacgagaagccccagctcttgccc
ttgcagcctcccacggagacgggcgtcccagccatgttcaccttccacgtgaatccagta
ctcagctccaggctggaggtgggcctaggaaagaagctcatggtccagggcgacccgagg
gtcaaggaggagacccagaccagcaagcctggcatcctgctctcatctctggccctaggc
caggagcagcagtgtgtcgtggccctgggggagggcaaggaggtggccattagtgtgaag
gcagagatgagctctggggaccttgacctgcgtcttggcttcgacctctgtgatggggag
aaggagtttctggagaagaggaagcggcttgtgtccaaggcctttcagcaggctttgggg
ttgagccacgctcctgatagtagccaggtgccagtggtggccgtgctgggttcaggaggt
gggacccgagccatgtcgtctttgtatggcagcctggctgggctacaggagctcggcctc
ttggacactgtgacctacctgagtggggtctccgggtccacctggtgcatctccacactc
tacaaggacccagcctggtcccaggtggccttgcagggccctattgagcgtgcccaggct
cgggtgtgcagcagtaagatgggggcaatgtccacggagcgcctgcattactacgcccag
gaactgggaatccgggaaagcagtggccacagcacttccctcgttgacctctggggcctt
cttattgaatatttcttgtaccaggaggaaaatcctgccaagctgtctgaccagaaggag
gcagtcagccagggccagaacccttaccccatctacgccagcgtcaacgtccgcagcaac
gtcagtggggaggactttgcagagtggtgcgagttcaccccccatgaggtcggcttcccc
aagtatggcgcatatgttcccaccgagctctttggctcagacttcttcatggggcgcctg
ctgcagctccggcccgagtcccggatctgctacctgcagggtatgtggggcagcgccttt
gcagccagcctggatgagatcttcctgaagacctctggccggggcctcagcttcctagac
tggcgcaaagacagtgtgaacatcacagatgactgccaagacctccagcttcacaaacca
gggcggctgagaaccaggctcttcacccctcagggacccttctatcaggctttgctggac
atatgcacctcccggttgacctcagccaagaactccaacttcacccggggcctctacctg
cacgaggactatgcgtctggcagggagtttgtggcctggaaagatttgcatccagacgcc
ttccccaaccagctcactcccatgagggactgtctatacttggtggacggaggctttgcc
atcaactccccattcccgctgagcctgcagccacaaagagctgtggacctcattctgtcc
ttcgactattccctggatgccccttttgaggtcttacagatgacagagaagtactgcctg
gaccgaggcatctccttccctaggattgaggtgtccccggaggacataaaggaaccccac
gagtgctacctgtttgccaaggctgaggacccaagctcacccatcatactgcacttcccc
ctggtcaaccgtaccttccgcacacacctggccccaggtgtggagcgaaaaacggctgag
gagaaggctggtggggactttgtcatcaacgggccagacactccctatggcatgatgaac
ttcacctacgagccccaagagtttgagcagctggtggccctgagtcgatacaatgtcctg
aacaatgtggagactgtgcggaaggccctccagctggctctagaccggcgacagactggg
gacaggactggaggctga

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