KEGG   Ovis aries (sheep): 101120753
Entry
101120753         CDS       T03117                                 
Symbol
SLC8A3
Name
(RefSeq) sodium/calcium exchanger 3 isoform X1
  KO
K05849  solute carrier family 8 (sodium/calcium exchanger)
Organism
oas  Ovis aries (sheep)
Pathway
oas04020  Calcium signaling pathway
oas04022  cGMP-PKG signaling pathway
oas04260  Cardiac muscle contraction
oas04261  Adrenergic signaling in cardiomyocytes
oas04371  Apelin signaling pathway
oas04740  Olfactory transduction
oas04961  Endocrine and other factor-regulated calcium reabsorption
oas04974  Protein digestion and absorption
oas04978  Mineral absorption
oas05410  Hypertrophic cardiomyopathy
oas05412  Arrhythmogenic right ventricular cardiomyopathy
oas05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    101120753 (SLC8A3)
   04020 Calcium signaling pathway
    101120753 (SLC8A3)
   04022 cGMP-PKG signaling pathway
    101120753 (SLC8A3)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    101120753 (SLC8A3)
   04261 Adrenergic signaling in cardiomyocytes
    101120753 (SLC8A3)
  09154 Digestive system
   04974 Protein digestion and absorption
    101120753 (SLC8A3)
   04978 Mineral absorption
    101120753 (SLC8A3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    101120753 (SLC8A3)
  09157 Sensory system
   04740 Olfactory transduction
    101120753 (SLC8A3)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101120753 (SLC8A3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101120753 (SLC8A3)
   05414 Dilated cardiomyopathy
    101120753 (SLC8A3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:oas02000]
    101120753 (SLC8A3)
   00536 Glycosaminoglycan binding proteins [BR:oas00536]
    101120753 (SLC8A3)
Transporters [BR:oas02000]
 Solute carrier family (SLC)
  SLC8: Na+/Ca2+ exchanger
   101120753 (SLC8A3)
Glycosaminoglycan binding proteins [BR:oas00536]
 Heparan sulfate / Heparin
  Others
   101120753 (SLC8A3)
SSDB
Motif
Pfam: Calx-beta Na_Ca_ex_C Na_Ca_ex
Other DBs
NCBI-GeneID: 101120753
NCBI-ProteinID: XP_027827765
EnsemblRapid: ENSOARG00020004383
Position
7:complement(79861677..80028457)
AA seq 928 aa
MAWLRLQPLTSAFLHFGLITFVLFLNGLRAEAGSSGDVPSTGQNNESCTGSSDCKEGVIL
PIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGE
TSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFI
IIGICVYVIPDGETRKIKHLRVFFVTAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFF
FPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGH
LVPLEGKEVDESRREMIRILKDLKQKYPEKDLDQLVEMANYYALSHQQKSRAFYRIQATR
MMTGAGNILKKHAAEQAKKTSSMSEVHADEPEDFVSKVFFDPCSYQCLENCGAVLLTVVR
KGGDTSKTLYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHF
FVRLSNVRMEEEQPEEGMSPRVRNSLPLPRAVLVSPCVATVTILDDDHAGIFTFECDTIH
VSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDIYGELEFKNDETVKTVHI
KVIDGEAYEKNKNYFLEMMVPRMVDMSFQKALLLSPEVTDRKLTVEEEEAKRIAEMGKPI
LGEHPKLEVIIEESYEFKTTVDKLIRKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDES
GEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFVVSILIIGMLTAIIGDLASHF
GCTIGLKDSVTAVIFVAFGTSVPDTFASKAAAIQDVYADASIGNVTGSNAVNVFLGIGLA
WSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKL
ATTWLFVSLWLLYILFATLEAYCYIKGF
NT seq 2787 nt   +upstreamnt  +downstreamnt
atggcgtggttaaggttgcagcctctcacctctgccttcctccattttgggctgattacc
tttgtgctcttcctgaatggtcttcgggcagaggctggcagctcaggggatgtgcccagc
acagggcagaacaatgagtcctgtacagggtcatcggactgcaaggagggtgtcatcctg
cccatctggtacccggagaacccttcccttggagacaagattgccagggtcattgtctat
tttgtggccctgatatacatgttcctcggggtgtccatcattgctgatcgcttcatggca
tctattgaagtcatcacttctcaagagagagaggtgactatcaaaaagcccaatggagag
accagcacaaccaccattagggtctggaacgaaactgtctccaacctgactcttatggcc
ctgggttcctctgctcctgagatcctcctgtctttaattgaggtatgtggtcatgggttc
attgctggtgatctgggaccttctaccattgtcggcagtgcagccttcaatatgttcatt
atcattggtatctgcgtctatgtgatccccgatggagagactcgcaagattaagcaccta
cgagtcttctttgtcactgctgcttggagcatctttgcctacatctggctctatatgatc
ctggctgtcttctctcctggtgtggtccaggtttgggaaggcctcctcactctcttcttc
tttccagtgtgtgtccttctggcctgggtggcagataagcgactgctcttctacaaatac
atgcacaaaaagtaccgcacagataaacaccgaggaattatcatagagaccgagggcgac
caccccaagggcattgagatggatgggaaaatgatgaattcccacttccttgatgggcac
ctggtgcccctggaagggaaggaagtggatgagtcccgcagggagatgatacggattctc
aaggacctgaagcaaaaatacccagagaaggacttagatcagctggtcgagatggccaac
tactatgctctctcccatcagcagaagagccgcgccttctaccggatccaggccacccgt
atgatgactggtgcgggcaatatcctgaagaagcacgcagcagaacaagccaaaaagacc
tccagcatgagcgaggtacatgccgacgagccggaggactttgtctccaaggtcttcttt
gacccgtgctcttaccagtgcctggagaactgtggggctgtgctcctgacagtggtgagg
aaaggcggggacacgtccaagaccctgtatgtggactacaaaacagaggatggttctgcc
aacgcaggggctgactatgagttcacagagggcactgtggttctaaagcccggagagacc
cagaaggagttctctgtgggcatcatcgatgatgacatttttgaggaggatgagcacttc
tttgtgaggctgagcaacgttcgcatggaggaggagcagcccgaggaggggatgtctccc
agagtacgcaatagtcttcccttgcctcgggctgtcctggtgtccccttgtgtggccaca
gtcaccatcttggatgatgaccacgcaggcatcttcacttttgaatgtgacactattcat
gtcagtgaaagcattggtgtcatggaggtcaaggttctgcggacatcaggtgcccggggc
acagtcatcgtcccctttaggacagtagaagggaccgccaagggtggtggtgaggatttt
gaagacatatatggggagttggagttcaagaatgatgaaaccgtcaaaacagttcacatc
aaggtaattgatggtgaggcgtatgagaaaaacaagaattacttccttgagatgatggtc
ccccgcatggtggatatgagttttcagaaagcgctcctgttatcgccagaggtgacagac
aggaagctgactgtggaagaagaagaagccaagaggatagcagaaatgggaaagccaata
ttgggtgaacaccccaaactagaggtcatcatcgaggagtcctatgagttcaagactacc
gtggacaagctgattaggaagacaaacctggccttggtcgtggggacccattcctggagg
gaccagttcatggaggccatcactgtcagtgcagcaggggacgaggatgaggatgagtca
ggcgaggagaggctgccttcctgctttgactacgtcatgcacttcctcacggtcttctgg
aaggtgctgtttgcctgcgtgccccccacagagtactgccacggctgggcctgcttcgtt
gtctccattctcatcatcggcatgctcaccgccatcatcggggacctggcctcccacttc
ggctgcaccattggcctcaaggactcggtcacggctgttatttttgtggcattcggcacc
tccgtgccagatacgtttgccagcaaagcggctgccatccaggacgtgtacgcagacgcc
tccatcggcaacgtcacgggcagcaacgccgtcaatgtcttcctgggcattggcctggcc
tggtccgtggccgccatctactgggccctgcagggacaggagttccacgtgtcggccggc
acgctggccttctccgtcaccctcttcaccatcttcgcgttcgtgtgcatcagcgtgctc
ttgtaccgccggcggccccacctgggcggggagctgggcggccctcgtggctgcaagctg
gccacgacttggctctttgtgagcctgtggcttctctacatactctttgccacgctggag
gcctactgctacatcaaggggttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (3)   
   Pfam (3)   
All databases (37)   

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