KEGG   Ovis aries (sheep): 443318
Entry
443318            CDS       T03117                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I precursor
  KO
K05459  insulin-like growth factor 1
Organism
oas  Ovis aries (sheep)
Pathway
oas01521  EGFR tyrosine kinase inhibitor resistance
oas01522  Endocrine resistance
oas04010  MAPK signaling pathway
oas04014  Ras signaling pathway
oas04015  Rap1 signaling pathway
oas04066  HIF-1 signaling pathway
oas04068  FoxO signaling pathway
oas04114  Oocyte meiosis
oas04115  p53 signaling pathway
oas04150  mTOR signaling pathway
oas04151  PI3K-Akt signaling pathway
oas04152  AMPK signaling pathway
oas04211  Longevity regulating pathway
oas04213  Longevity regulating pathway - multiple species
oas04510  Focal adhesion
oas04550  Signaling pathways regulating pluripotency of stem cells
oas04730  Long-term depression
oas04750  Inflammatory mediator regulation of TRP channels
oas04913  Ovarian steroidogenesis
oas04914  Progesterone-mediated oocyte maturation
oas04935  Growth hormone synthesis, secretion and action
oas04960  Aldosterone-regulated sodium reabsorption
oas05200  Pathways in cancer
oas05202  Transcriptional misregulation in cancer
oas05205  Proteoglycans in cancer
oas05214  Glioma
oas05215  Prostate cancer
oas05218  Melanoma
oas05224  Breast cancer
oas05410  Hypertrophic cardiomyopathy
oas05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    443318 (IGF1)
   04014 Ras signaling pathway
    443318 (IGF1)
   04015 Rap1 signaling pathway
    443318 (IGF1)
   04066 HIF-1 signaling pathway
    443318 (IGF1)
   04068 FoxO signaling pathway
    443318 (IGF1)
   04151 PI3K-Akt signaling pathway
    443318 (IGF1)
   04152 AMPK signaling pathway
    443318 (IGF1)
   04150 mTOR signaling pathway
    443318 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    443318 (IGF1)
   04115 p53 signaling pathway
    443318 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    443318 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    443318 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    443318 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    443318 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    443318 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    443318 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    443318 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    443318 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    443318 (IGF1)
   04213 Longevity regulating pathway - multiple species
    443318 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    443318 (IGF1)
   05202 Transcriptional misregulation in cancer
    443318 (IGF1)
   05205 Proteoglycans in cancer
    443318 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    443318 (IGF1)
   05218 Melanoma
    443318 (IGF1)
   05215 Prostate cancer
    443318 (IGF1)
   05224 Breast cancer
    443318 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    443318 (IGF1)
   05414 Dilated cardiomyopathy
    443318 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    443318 (IGF1)
   01522 Endocrine resistance
    443318 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:oas04052]
    443318 (IGF1)
Cytokines and neuropeptides [BR:oas04052]
 Cytokines
  Growth factors (RTK binding)
   443318 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 443318
NCBI-ProteinID: NP_001009774
EnsemblRapid: ENSOARG00020009650
UniProt: P10763 A0A836D4F5 A0FJ28
Position
3:complement(171766875..171847317)
AA seq 154 aa
MGKISSLPTQLFKCCFCDFLKQVKMPVTSSSHLFYLALCLLAFSSSATAGPETLCGAELV
DALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKAAKSAR
SVRAQRHTDMPKAQKEVHLKNTSRGSAGNKNYRM
NT seq 465 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aagcaggtgaagatgccagtcacatcctcctcgcatctcttctatctggccctgtgcttg
ctcgccttcagcagctctgccacggcgggacctgagaccctctgcggggctgagttggtg
gatgctctccagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtac
ggctcgagcagtcggagggcgccccagacaggaatcgtggatgagtgctgcttccggagc
tgtgatctgaggaggctggagatgtactgtgcgcctctcaaggccgccaagtcggcccgc
tcagtccgtgcccagcgccacaccgacatgcccaaggctcagaaggaagtacatttgaag
aacacaagcagagggagtgcaggaaacaagaactacagaatgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (31)   
   KEGG PATHWAY (31)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (35)   
   RefSeq(nuc) (13)   
   GenBank (11)   
   EMBL (11)   
Protein domain (1)   
   Pfam (1)   
All databases (92)   

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