KEGG   Ovis aries (sheep): 443453
Entry
443453            CDS       T03117                                 
Symbol
CAMK2A
Name
(RefSeq) calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
  KO
K04515  calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Organism
oas  Ovis aries (sheep)
Pathway
oas04012  ErbB signaling pathway
oas04020  Calcium signaling pathway
oas04024  cAMP signaling pathway
oas04066  HIF-1 signaling pathway
oas04114  Oocyte meiosis
oas04148  Efferocytosis
oas04217  Necroptosis
oas04261  Adrenergic signaling in cardiomyocytes
oas04310  Wnt signaling pathway
oas04360  Axon guidance
oas04713  Circadian entrainment
oas04720  Long-term potentiation
oas04722  Neurotrophin signaling pathway
oas04725  Cholinergic synapse
oas04728  Dopaminergic synapse
oas04740  Olfactory transduction
oas04750  Inflammatory mediator regulation of TRP channels
oas04911  Insulin secretion
oas04912  GnRH signaling pathway
oas04916  Melanogenesis
oas04921  Oxytocin signaling pathway
oas04922  Glucagon signaling pathway
oas04925  Aldosterone synthesis and secretion
oas04934  Cushing syndrome
oas04971  Gastric acid secretion
oas05012  Parkinson disease
oas05022  Pathways of neurodegeneration - multiple diseases
oas05031  Amphetamine addiction
oas05152  Tuberculosis
oas05200  Pathways in cancer
oas05205  Proteoglycans in cancer
oas05214  Glioma
oas05415  Diabetic cardiomyopathy
oas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    443453 (CAMK2A)
   04310 Wnt signaling pathway
    443453 (CAMK2A)
   04066 HIF-1 signaling pathway
    443453 (CAMK2A)
   04020 Calcium signaling pathway
    443453 (CAMK2A)
   04024 cAMP signaling pathway
    443453 (CAMK2A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    443453 (CAMK2A)
  09143 Cell growth and death
   04114 Oocyte meiosis
    443453 (CAMK2A)
   04217 Necroptosis
    443453 (CAMK2A)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    443453 (CAMK2A)
   04922 Glucagon signaling pathway
    443453 (CAMK2A)
   04912 GnRH signaling pathway
    443453 (CAMK2A)
   04921 Oxytocin signaling pathway
    443453 (CAMK2A)
   04916 Melanogenesis
    443453 (CAMK2A)
   04925 Aldosterone synthesis and secretion
    443453 (CAMK2A)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    443453 (CAMK2A)
  09154 Digestive system
   04971 Gastric acid secretion
    443453 (CAMK2A)
  09156 Nervous system
   04725 Cholinergic synapse
    443453 (CAMK2A)
   04728 Dopaminergic synapse
    443453 (CAMK2A)
   04720 Long-term potentiation
    443453 (CAMK2A)
   04722 Neurotrophin signaling pathway
    443453 (CAMK2A)
  09157 Sensory system
   04740 Olfactory transduction
    443453 (CAMK2A)
   04750 Inflammatory mediator regulation of TRP channels
    443453 (CAMK2A)
  09158 Development and regeneration
   04360 Axon guidance
    443453 (CAMK2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    443453 (CAMK2A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    443453 (CAMK2A)
   05205 Proteoglycans in cancer
    443453 (CAMK2A)
  09162 Cancer: specific types
   05214 Glioma
    443453 (CAMK2A)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    443453 (CAMK2A)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    443453 (CAMK2A)
   05022 Pathways of neurodegeneration - multiple diseases
    443453 (CAMK2A)
  09165 Substance dependence
   05031 Amphetamine addiction
    443453 (CAMK2A)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    443453 (CAMK2A)
   05415 Diabetic cardiomyopathy
    443453 (CAMK2A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    443453 (CAMK2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oas01001]
    443453 (CAMK2A)
Enzymes [BR:oas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     443453 (CAMK2A)
Protein kinases [BR:oas01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   443453 (CAMK2A)
SSDB
Motif
Pfam: Pkinase CaMKII_AD PK_Tyr_Ser-Thr DUF4440 SnoaL_3 SnoaL_2 APH Kdo SnoaL_4
Other DBs
NCBI-GeneID: 443453
NCBI-ProteinID: XP_004009021
EnsemblRapid: ENSOARG00020012100
UniProt: A0A6P3E9R3
Position
5:complement(59337153..59402652)
AA seq 489 aa
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR
SGAPSVLPH
NT seq 1470 nt   +upstreamnt  +downstreamnt
atggccaccatcacctgcacccgcttcacggaagagtaccagctcttcgaggaactagga
aagggagccttctcagtggtgcgcaggtgtgtgaaggtgctggccggccaggaatatgct
gccaagattatcaacacgaagaagctctcagccagagaccaccagaagctggagcgtgaa
gcccgcatttgccgcctgctgaagcaccccaatatcgtccggctccatgacagcatctct
gaggagggacaccattacctgatctttgacctcgtcaccggcggggagctgtttgaagac
atcgtggcccgggagtattacagtgaggcggatgccagtcactgcatccagcagatcctg
gaggctgtgctgcactgccaccagatgggggtggtgcaccgggaccttaagccggagaac
ctgttgctggcctccaagctcaagggcgctgcagtgaagctggcggactttggcctggcc
atagaggtagagggcgagcagcaggcatggtttgggttcgcagggacacccggatacctc
tccccagaagtgctgcggaaggacccatacgggaagcccgtggacctgtgggcctgcggg
gtcatcctgtacattctgctggtggggtaccccccgttctgggatgaggaccagcatcgc
ctgtaccagcagatcaaagctggcgcctatgatttcccatcaccagaatgggacaccgtt
accccggaagccaaggatctgatcaataagatgctgaccatcaacccatccaaacgcatc
acagccgctgaggccctcaagcacccctggatctcgcaccggtccactgtggcctcctgc
atgcacagacaggagaccgtggactgcctgaagaagttcaacgccaggagaaaactgaag
ggagccatcctcaccactatgctggccaccaggaacttctctggcgggaagagtggggga
aacaagaagaacgatggtgtgaagaaaagaaagtccagttccagcgttcagttaatggaa
tcttcagagagcaccaataccaccattgaggatgaagacaccaaagtgcggaaacaagag
atcataaaagtgacagagcagctgattgaagccataagcaatggagactttgagtcctac
acgaaaatgtgtgaccctgggatgacggccttcgaacccgaggccctggggaacctggtc
gagggcctggacttccatcgattctattttgaaaacctgtggtcccggaacagcaagcct
gtgcacaccaccatcctgaacccccacatccacctgatgggtgacgagtcggcctgcatc
gcctacatccgcatcacgcagtacctggacgccggcggcatcccccgcacggcccagtcg
gaagagactcgcgtctggcaccgccgggatggcaaatggcagatcgtccacttccacaga
tccggggcgccttccgtcctgccgcactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (34)   
   KEGG PATHWAY (34)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (60)   

Download RDF
DBGET integrated database retrieval system