KEGG   Oryctolagus cuniculus (rabbit): 100008993
Entry
100008993         CDS       T03373                                 

Gene name
MMP9
Definition
(RefSeq) matrix metallopeptidase 9
  KO
K01403  matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04657  IL-17 signaling pathway
ocu04668  TNF signaling pathway
ocu04670  Leukocyte transendothelial migration
ocu04915  Estrogen signaling pathway
ocu04926  Relaxin signaling pathway
ocu05161  Hepatitis B
ocu05200  Pathways in cancer
ocu05202  Transcriptional misregulation in cancer
ocu05205  Proteoglycans in cancer
ocu05206  MicroRNAs in cancer
ocu05215  Prostate cancer
ocu05219  Bladder cancer
ocu05415  Diabetic cardiomyopathy
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    100008993 (MMP9)
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    100008993 (MMP9)
   04670 Leukocyte transendothelial migration
    100008993 (MMP9)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    100008993 (MMP9)
   04926 Relaxin signaling pathway
    100008993 (MMP9)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100008993 (MMP9)
   05202 Transcriptional misregulation in cancer
    100008993 (MMP9)
   05206 MicroRNAs in cancer
    100008993 (MMP9)
   05205 Proteoglycans in cancer
    100008993 (MMP9)
  09162 Cancer: specific types
   05219 Bladder cancer
    100008993 (MMP9)
   05215 Prostate cancer
    100008993 (MMP9)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100008993 (MMP9)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100008993 (MMP9)
   05418 Fluid shear stress and atherosclerosis
    100008993 (MMP9)
   05415 Diabetic cardiomyopathy
    100008993 (MMP9)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100008993 (MMP9)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ocu01002]
    100008993 (MMP9)
Enzymes [BR:ocu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.35  gelatinase B
     100008993 (MMP9)
Peptidases and inhibitors [BR:ocu01002]
 Metallo peptidases
  Family M10
   100008993 (MMP9)
SSDB
Motif
Pfam: Peptidase_M10 fn2 Hemopexin PT PG_binding_1 Peptidase_M66 Reprolysin_3 Reprolysin_4 DUF4953
Other DBs
NCBI-GeneID: 100008993
NCBI-ProteinID: NP_001075672
Ensembl: ENSOCUG00000016101
UniProt: P41246
Position
Un
AA seq 707 aa
MSPRQPLVLALLVLGCCSAAPRRRQPTLVVFPGELRTRLTDRQLAEEYLFRYGYTRVASM
HGDSQSLRLPLLLLQKHLSLPETGELDNATLEAMRAPRCGVPDVGKFQTFEGDLKWHHHN
ITYWIQNYSEDLPRDVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYP
FDGKDGLLAHAFPPGPGIQGDAHFDDEELWSLGKGVVVPTYFGNADGAPCHFPFTFEGRS
YTACTTDGRSDGMAWCSTTADYDTDRRFGFCPSERLYTQDGNADGKPCEFPFIFQGRTYS
ACTTDGRSDGHRWCATTASYDKDKLYGFCPTRADSTVVGGNSAGELCVFPFVFLGKEYSS
CTSEGRRDGRLWCATTSNFDSDKKWGFCPDKGYSLFLVAAHEFGHALGLDHSSVPERLMY
PMYRYLEGSPLHEDDVRGIQHLYGPNPNPQPPATTTPEPQPTAPPTACPTWPATVRPSEH
PTTSPTGAPSAGPTGPPTASPSAAPTASLDPAEDVCNVNVFDAIAEIGNKLHVFKDGRYW
RFSEGSGRRPQGPFLIADTWPALPAKLDSAFEEPLTKKLFFFSGRQVWVYTGASVLGPRR
LDKLGLGPEVPHVTGALPRAGGKVLLFGAQRFWRFDVKTQTVDSRSGAPVDQMFPGVPLN
THDVFQYREKAYFCQDRFFWRVSTRNEVNLVDQVGYVSFDILHCPED
NT seq 2124 nt   +upstreamnt  +downstreamnt
atgagccccagacagcccctggtcctggcgctcctcgtgctgggctgttgctcagccgcc
cctcgccgccgccagcccaccttggtggtcttcccaggagagctgagaaccaggctcacc
gacaggcagctggcagaggagtacctgttccgctatggttacacccgcgtagccagcatg
cacggagacagccagtccctgcggctgccgctgctacttctgcagaagcatctgtccctg
ccggagacgggggagctggataatgccaccctggaggccatgcgggccccgcgctgcggc
gtcccggacgtgggcaaattccagaccttcgagggtgacctcaagtggcaccaccacaac
atcacgtactggatccaaaactactccgaagacctgccgcgcgacgtcatcgacgacgcc
ttcgcccgcgcctttgcgctgtggagcgcggtgacgccactcaccttcacccgcgtgtac
agccgggacgcagacattgtcatccagtttggggtcgcggagcacggagacgggtatcct
ttcgacggcaaggacgggctcctggcgcacgccttccctcctggccccggcattcaggga
gatgcccacttcgacgacgaagagctgtggtccctgggcaagggcgtcgtggttcccacg
tactttggaaacgccgacggcgccccctgccacttccccttcaccttcgagggccgctcc
tacaccgcctgcaccacggacggccgctctgacggcatggcctggtgcagcaccacggcc
gactatgacaccgaccgtcggtttggcttctgccccagcgaaagactctacacccaggac
ggcaacgcagacggcaagccctgcgagtttccgttcatcttccagggccgtacctactcc
gcctgcaccacggacggccgctccgacggccaccgctggtgcgccaccaccgccagctac
gacaaggacaagctctacggcttctgcccgacccgagctgactccacggtggtcgggggc
aactcggcgggagagctgtgtgtcttccccttcgtcttcctgggcaaagagtactcgtcc
tgtaccagcgagggtcgcagggatgggcgcctctggtgtgccaccacttccaactttgac
agcgacaagaagtggggcttctgccctgataaaggatacagcctgttcctcgtggcagcc
cacgagttcggccatgcactgggcttggatcactcctctgtgccggagcgcctcatgtac
cccatgtaccgctacctagaggggtcccccctgcacgaggacgacgtcaggggcatccag
catctatatggtcctaaccccaacccccagcctccagccaccaccacacctgagccgcag
cccacggctcccccgacggcctgccccacctggccggccactgtgcgcccctccgagcac
cccactaccagccctaccggcgccccctcagctggccctaccggtccccccacggccagc
ccctctgcggcccccactgcgtccttggacccagctgaagacgtctgcaacgtgaatgtc
ttcgacgccatcgccgagatagggaacaagctgcatgtcttcaaggatgggaggtactgg
cggttctccgagggcagtgggcgccggccgcagggccccttcctcatcgccgacacctgg
cccgcgctgccggccaagctggactccgcctttgaggagccgctcaccaagaagctgttc
ttcttctcggggcgccaagtgtgggtgtacacaggcgcgtcggtgctgggcccgaggcgt
ctggacaagctgggcctgggtcccgaggtgccgcacgtcaccggagccctcccgcgcgcc
gggggcaaggtgctgctgttcggcgcgcagcgcttctggaggttcgacgtgaagacgcag
acggtggattcccggagcggcgctccggtggatcagatgttccccggggtgcctttgaac
acacacgacgtcttccagtaccgagagaaagcctacttctgccaggaccgcttcttctgg
cgtgtgagtacccggaacgaggtgaacctagtggaccaggtgggctacgtgagctttgac
atcctgcactgccctgaggactag

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