KEGG   Oryctolagus cuniculus (rabbit): 100009073
Entry
100009073         CDS       T03373                                 
Symbol
GSTM2
Name
(RefSeq) glutathione S-transferase Mu 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00480  Glutathione metabolism
ocu00980  Metabolism of xenobiotics by cytochrome P450
ocu00982  Drug metabolism - cytochrome P450
ocu00983  Drug metabolism - other enzymes
ocu01100  Metabolic pathways
ocu01524  Platinum drug resistance
ocu05200  Pathways in cancer
ocu05204  Chemical carcinogenesis - DNA adducts
ocu05207  Chemical carcinogenesis - receptor activation
ocu05208  Chemical carcinogenesis - reactive oxygen species
ocu05225  Hepatocellular carcinoma
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100009073 (GSTM2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100009073 (GSTM2)
   00982 Drug metabolism - cytochrome P450
    100009073 (GSTM2)
   00983 Drug metabolism - other enzymes
    100009073 (GSTM2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100009073 (GSTM2)
   05204 Chemical carcinogenesis - DNA adducts
    100009073 (GSTM2)
   05207 Chemical carcinogenesis - receptor activation
    100009073 (GSTM2)
   05208 Chemical carcinogenesis - reactive oxygen species
    100009073 (GSTM2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100009073 (GSTM2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100009073 (GSTM2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100009073 (GSTM2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ocu02000]
    100009073 (GSTM2)
Enzymes [BR:ocu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100009073 (GSTM2)
Transporters [BR:ocu02000]
 Other transporters
  Pores ion channels [TC:1]
   100009073 (GSTM2)
SSDB
Motif
Pfam: GST_C GST_N GST_C_3 GST_N_3 GST_N_2 GST_C_6 GST_C_2
Other DBs
NCBI-GeneID: 100009073
NCBI-ProteinID: NP_001075721
UniProt: P46409
Position
13:complement(54701700..54707086)
AA seq 218 aa
MPMTLGYWDVRGLALPIRMLLEYTDTSYEEKKYTMGDAPNYDQSKWLSEKFTLGLDFPNL
PYLIDGTHKLTQSNAILRYLARKHGLCGETEEERIRVDILENQLMDNRFQLVNVCYSPDF
EKLKPEYLKGLPEKLQLYSQFLGSLPWFAGDKITFADFLVYDVLDQNRIFVPGCLDAFPN
LKDFHVRFEGLPKISAYMKSSRFIRVPVFLKKATWTGI
NT seq 657 nt   +upstreamnt  +downstreamnt
atgcccatgacgctgggttactgggacgtccgtgggctggctctgccaatccgcatgctc
ctggaatacacggacaccagctatgaggaaaagaaatacaccatgggggatgctcccaac
tatgaccaaagcaagtggctgagtgagaagttcaccctgggcctggactttcccaatctg
ccctacctaattgatgggactcacaagctcacgcagagcaacgccatcctgcgctacctg
gcccgcaagcacggcctgtgtggggagacggaagaggagaggattcgcgtggacattctg
gagaatcagctgatggacaaccgcttccaacttgtaaacgtctgctacagtcccgacttt
gagaagctcaagcccgagtacctgaaggggctccctgagaagctgcagctgtactcgcag
ttcctgggaagcctcccctggttcgcaggggacaagatcaccttcgccgatttccttgtc
tacgacgttcttgaccagaaccggatatttgtgcctgggtgcctggacgcgttcccaaac
ctgaaggactttcatgtccgctttgagggcctgccgaagatctctgcctacatgaagtcc
agccgctttatccgagtccctgtgtttttaaagaaggccacgtggacgggaatatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (124)   

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