KEGG   Oryctolagus cuniculus (rabbit): 100009274
Entry
100009274         CDS       T03373                                 
Symbol
ACE
Name
(RefSeq) angiotensin-converting enzyme isoform 1 precursor
  KO
K01283  peptidyl-dipeptidase A [EC:3.4.15.1]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04614  Renin-angiotensin system
ocu04924  Renin secretion
ocu05142  Chagas disease
ocu05171  Coronavirus disease - COVID-19
ocu05410  Hypertrophic cardiomyopathy
ocu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    100009274 (ACE)
   04614 Renin-angiotensin system
    100009274 (ACE)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100009274 (ACE)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100009274 (ACE)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100009274 (ACE)
   05415 Diabetic cardiomyopathy
    100009274 (ACE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ocu01002]
    100009274 (ACE)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ocu04147]
    100009274 (ACE)
   04090 CD molecules [BR:ocu04090]
    100009274 (ACE)
Enzymes [BR:ocu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.15  Peptidyl-dipeptidases
    3.4.15.1  peptidyl-dipeptidase A
     100009274 (ACE)
Peptidases and inhibitors [BR:ocu01002]
 Metallo peptidases
  Family M2
   100009274 (ACE)
Exosome [BR:ocu04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   100009274 (ACE)
CD molecules [BR:ocu04090]
 Proteins
  100009274 (ACE)
SSDB
Motif
Pfam: Peptidase_M2 Peptidase_M32
Other DBs
NCBI-GeneID: 100009274
NCBI-ProteinID: NP_001075864
Ensembl: ENSOCUG00000001555
UniProt: P12822
Position
19:45862887..45882079
AA seq 1310 aa
MGAAPGRRGPRLLRPPPPLLLLLLLLRPPPAALTLDPGLLPGDFAADEAGARLFASSYNS
SAEQVLFRSTAASWAHDTNITAENARRQEEEALLSQEFAEAWGKKAKELYDPVWQNFTDP
ELRRIIGAVRTLGPANLPLAKRQQYNSLLSNMSQIYSTGKVCFPNKTASCWSLDPDLNNI
LASSRSYAMLLFAWEGWHNAVGIPLKPLYQEFTALSNEAYRQDGFSDTGAYWRSWYDSPT
FEEDLERIYHQLEPLYLNLHAYVRRVLHRRYGDRYINLRGPIPAHLLGNMWAQSWESIYD
MVVPFPDKPNLDVTSTMVQKGWNATHMFRVAEEFFTSLGLLPMPPEFWAESMLEKPEDGR
EVVCHASAWDFYNRKDFRIKQCTQVTMDQLSTVHHEMGHVQYYLQYKDQPVSLRRANPGF
HEAIGDVLALSVSTPAHLHKIGLLDHVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRW
GVFSGRTPSSRYNFDWWYLRTKYQGICPPVVRNETHFDAGAKFHIPSVTPYIRYFVSFVL
QFQFHQALCMEAGHQGPLHQCDIYQSTRAGAKLRAVLQAGCSRPWQEVLKDMVASDALDA
QPLLDYFQPVTQWLQEQNERNGEVLGWPEYQWRPPLPNNYPEGIDLVTDEAEASRFVEEY
DRSFQAVWNEYAEANWNYNTNITTEASKILLQKNMQIANHTLTYGNWARRFDVSNFQNAT
SKRIIKKVQDLQRAVLPVKELEEYNQILLDMETIYSVANVCRVDGSCLQLEPDLTNLMAT
SRKYDELLWVWTSWRDKVGRAILPYFPKYVEFTNKAARLNGYVDAGDSWRSMYETPTLEQ
DLERLFQELQPLYLNLHAYVGRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVA
PFPSASTMDATEAMIKQGWTPRRMFEEADKFFISLGLLPVPPEFWNKSMLEKPTDGREVV
CHASAWDFYNGKDFRIKQCTTVNMEDLVVVHHEMGHIQYFMQYKDLPVALREGANPGFHE
AIGDVLALSVSTPKHLHSINLLSSEGGGYEHDINFLMKMALDKIAFIPFSYLVDEWRWRV
FDGSITKENYNQEWWSLRLKYQGLCPPAPRSQGDFDPGAKFHIPSSVPYIRYFVSFIIQF
QFHEALCKAAGHTGPLHTCDIYQSKEAGKRLADAMKLGYSKPWPEAMKVITGQPNMSASA
MMNYFKPLMDWLLTENGRHGEKLGWPQYTWTPNSARSEGSLPDSGRVNFLGMNLDAQQAR
VGQWVLLFLGVALLLASLGLTQRLFSIRYQSLRQPHHGPQFGSEVELRHS
NT seq 3933 nt   +upstreamnt  +downstreamnt
atgggggccgcgccgggccgccgggggccgaggctgctgcggccgccgccgccgctgctg
ctgctgctcctgctgctgcggccgccgcccgccgccctgacgctggaccctgggctgctg
cccggcgactttgccgccgacgaggccggcgcgcggctcttcgcgagcagctacaactcg
agcgccgagcaggttctgtttcggagcaccgcagccagctgggcgcacgacaccaacatc
accgcggagaacgcaaggcgccaggaggaagaagccctgctcagccaagagtttgcagag
gcctggggcaagaaggctaaggagctctatgacccggtgtggcagaacttcaccgaccca
gagctgcgcaggatcatcggggctgtgcgcaccctgggccctgccaacctgcccctggcc
aagcggcagcagtacaactctctgctgagcaacatgagccaaatctactccacgggcaag
gtctgcttccccaacaagactgccagctgctggtccctggacccagacctcaacaacatc
ctggcttcctcacggagctacgccatgctgctgtttgcctgggagggctggcacaatgcc
gtgggcatcccattgaagcccctctaccaggaattcaccgcgctcagcaacgaggcctac
cggcaggatggcttctcggacacgggggcctactggcgctcctggtatgactcgcccacc
ttcgaggaggacctggagcgcatctaccatcagttagagcccctctacctgaacctgcac
gcctatgtccggcgagtgctccaccgccgctacggggacagatacatcaacctcagggga
cccatccccgcacacctgctggggaacatgtgggcccagagctgggaaagcatctacgac
atggtggtgccctttccagacaagcccaacctggatgtcaccagcaccatggtgcagaag
ggctggaatgctacacacatgttccgggtggccgaggagttcttcacctccctggggctc
ttacccatgcctcctgaattctgggctgagtcgatgctggagaagccggaggatgggcgg
gaggtggtgtgccacgcctcggcctgggacttctacaaccggaaggacttcaggattaag
cagtgcacgcaggtgacgatggaccagctgtccacggtgcaccatgagatgggccacgtg
cagtactacctccagtacaaagaccaacctgtctccctgcgccgagccaaccccggcttc
cacgaggccatcggcgacgtgctagcgctgtcagtctccacgcctgcacatctgcacaaa
atcggtctcctggaccacgtcaccaatgacacagaaagtgacatcaattacttgctgaag
atggcactggaaaaaatcgccttcctgccctttggctatttggtggaccagtggcgctgg
ggggtcttcagtgggcggacgccctcttcccgctacaactttgactggtggtatcttcgc
accaagtatcagggcatctgccctcccgtcgtgagaaatgagacccactttgatgccgga
gctaagttccatatcccaagtgtgacgccgtacatcaggtactttgtgagctttgtcctg
cagttccagttccatcaagccctgtgcatggaggccggccaccagggtccactgcaccag
tgtgacatctaccagtccacccgcgcaggggccaagctccgggcggtgctgcaggcaggc
tgctccaggccctggcaggaggtgctcaaggacatggtcgcctccgacgccctggacgcc
cagccgctgctcgactacttccagccagtcacccagtggctgcaggagcagaacgagcgc
aatggcgaggtcctgggctggccggagtatcagtggcgcccaccgctgcccaacaactac
ccggaaggcatcgacctggtgaccgatgaggctgaggccagccggttcgtggaggagtat
gaccggtcgttccaggcagtgtggaatgagtacgcggaggccaactggaactataacacc
aacatcaccacagaggccagcaagatcctgctgcagaaaaacatgcagatagccaaccac
accctcacgtacggcaactgggccaggaggtttgatgtgagcaacttccagaacgccacc
agcaagcgcatcataaagaaggttcaggacctgcagcgggcagtgctgcccgtcaaggag
ctggaggagtacaaccagatcctgctggacatggagaccatttacagcgtggccaacgtg
tgccgcgtggacggctcttgtctccagctggagcctgatctgaccaatctgatggccacg
tctcggaaatacgacgaactgttgtgggtgtggacaagctggcgggacaaggtggggaga
gccatcctcccgtattttccgaaatatgtggagttcaccaacaaggctgcccggctcaat
ggctacgttgatgcaggggactcctggaggtccatgtacgagacgccgaccctggagcaa
gacctggagcggctcttccaggagctgcagccgctctacctgaacctgcacgcctacgtc
ggccgcgccctgcaccgccactacggagcccagcacatcaacctggagggccccattcct
gcacacctgctggggaacatgtgggcgcagacctggtccaacatctatgacctggtggct
cctttcccttcagcctccacgatggatgccacagaggccatgatcaagcagggctggact
cccaggagaatgtttgaggaagctgacaagttcttcatctccctggggctgctgcccgtg
cctcccgagttctggaacaagtcgatgctggagaagcccaccgacgggcgggaggtggtg
tgccacgcctcggcctgggacttctacaatggcaaggatttcaggatcaagcagtgcacc
acggtgaacatggaggacctggtggtggtccaccacgagatgggtcacatccagtacttc
atgcagtacaaggacttgcccgtggccttgcgggagggcgccaaccccggctttcacgag
gccatcggggacgtgctggccctctcggtgtccacgcccaagcacttacacagcatcaac
ctgctgagcagcgagggcggcggctacgagcacgacatcaacttcctcatgaagatggca
ctcgacaagatcgcctttatccccttcagctacctcgtggacgagtggcgctggagggta
tttgacgggagcattaccaaggagaactacaaccaggagtggtggagcctcaggctgaag
taccagggcctctgtcccccggcgcctaggtctcaaggtgactttgatccaggggccaag
ttccacatcccttcaagtgtgccttacatcaggtactttgtcagcttcatcatccagttc
cagttccacgaggcactgtgcaaggcagctggccacactggccccttgcacacctgtgac
atctaccagtccaaggaggcagggaagcgcctggcggatgccatgaagctgggctacagt
aagccgtggccagaagccatgaaggtgattacaggccagcccaacatgtcagcctcggcc
atgatgaactacttcaagccgctgatggactggctcctcaccgagaacgggcggcacggg
gagaagctgggctggccgcagtacacctggactccaaactctgctcgctcggaaggctcc
ctcccagactccggccgcgtcaacttcctgggcatgaacctggacgcgcagcaggcccgc
gtgggccagtgggtgctgctcttcctgggcgtcgccttgctcttggccagcttgggcctc
acccagcggctcttcagtatccgctaccagagcctccgccagccccaccacgggccccag
ttcggctccgaggtggagctaagacactcctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (2)   
   Pfam (2)   
All databases (53)   

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