KEGG   Oryctolagus cuniculus (rabbit): 100341946
Entry
100341946         CDS       T03373                                 
Name
(RefSeq) hexokinase-4
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00010  Glycolysis / Gluconeogenesis
ocu00052  Galactose metabolism
ocu00500  Starch and sucrose metabolism
ocu00520  Amino sugar and nucleotide sugar metabolism
ocu00524  Neomycin, kanamycin and gentamicin biosynthesis
ocu01100  Metabolic pathways
ocu01200  Carbon metabolism
ocu01250  Biosynthesis of nucleotide sugars
ocu04910  Insulin signaling pathway
ocu04911  Insulin secretion
ocu04917  Prolactin signaling pathway
ocu04922  Glucagon signaling pathway
ocu04930  Type II diabetes mellitus
ocu04950  Maturity onset diabetes of the young
ocu05230  Central carbon metabolism in cancer
Module
ocu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ocu_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
ocu_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100341946
   00052 Galactose metabolism
    100341946
   00500 Starch and sucrose metabolism
    100341946
   00520 Amino sugar and nucleotide sugar metabolism
    100341946
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100341946
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100341946
   04910 Insulin signaling pathway
    100341946
   04922 Glucagon signaling pathway
    100341946
   04917 Prolactin signaling pathway
    100341946
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    100341946
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100341946
   04950 Maturity onset diabetes of the young
    100341946
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100341946
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1 Tho2
Other DBs
NCBI-GeneID: 100341946
NCBI-ProteinID: XP_008260040
Position
10:complement(41678031..41688871)
AA seq 466 aa
MTMEATRRQAQTATSLVEQILAEFQLHEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQLKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRMVDESSANPGQQLYEKLIGGKYMG
ELVRLLLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRKQTYNILSTLGLRP
SAADCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRGMDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLAQ
NT seq 1401 nt   +upstreamnt  +downstreamnt
atgaccatggaagccacaaggaggcaggcccagacagccacgagtctggtggagcagatc
ctggcggaattccagctgcacgaggaggacctgaagaaggtgatgcggcgcatgcagaag
gagatggaccgaggcctgcggctggagacccacgaggaggccagcgtgaagatgctgccc
acctacgtgcgctccaccccggaaggctcggaagtcggggacttcctctccctggacctg
ggtggcaccaacttccgggtgatgctggtgaaggtgggggagggcgaggaggggcagtgg
agcgtgaagaccaagcaccagatgtactccatccctgaggacgccatgaccggcaccgct
gagatgctcttcgactacatctccgagtgcatctccgacttcctggacaagcaccagctg
aagcacaagaagctgccactgggtttcaccttctcctttcctgtgcggcacgaagacatc
gacaagggcatcctcctcaactggaccaagggcttcaaggcctcgggggctgaagggaac
aacatcgtggggctcctgcgagatgccatcaagcgcagaggggactttgagatggacgtg
gtggccatggtgaacgacacggtggccaccatgatctcctgctactacgaagaccgccag
tgcgaggtcggcatgatcgtgggcactggctgcaacgcctgctacatggaggagatgcag
aacgtggagctggtggagggcgacgagggccgcatgtgcgtcaacaccgagtggggcgcc
ttcggggactcgggcgagctggacgagttcctgctggagtacgaccgcatggtggacgag
agctccgcgaaccccggtcagcagctgtacgaaaagctcatcggcggcaagtacatgggc
gagctggtgcggctcctgctgctgaagctggtggacgagaacctgctgttccacggcgag
gcctcggagcagctgcgcacgcgcggcgccttcgagacgcgctttgtgtcccaggtggag
agcgactccggggaccgcaagcagacctacaacatcctgagcacgctggggctgcggccc
tcggccgccgactgcgacatcgtgcggcgcgcctgcgagagcgtgtccacgcgcgccgcg
cacatgtgctcggccgggctggcgggcgtcatcaaccgcatgcgcgagagccgcggcatg
gacgtgatgcgcatcacggtgggcgtggacggctcggtgtacaagctgcaccccagcttc
aaggagcggttccacgccagcgtgcgcaggctgacgcccagctgcgagatcaccttcatc
gagtcggaggaaggcagcggccggggtgccgcgctggtctcggccgtggcctgcaagaag
gcctgcatgctggcccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (15)   
   KEGG MODULE (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (48)   

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