KEGG   Oryctolagus cuniculus (rabbit): 100350803
Entry
100350803         CDS       T03373                                 
Name
(RefSeq) serine/threonine-protein kinase ULK1 isoform X1
  KO
K21357  serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04137  Mitophagy - animal
ocu04140  Autophagy - animal
ocu04150  mTOR signaling pathway
ocu04152  AMPK signaling pathway
ocu04211  Longevity regulating pathway
ocu05010  Alzheimer disease
ocu05014  Amyotrophic lateral sclerosis
ocu05016  Huntington disease
ocu05017  Spinocerebellar ataxia
ocu05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    100350803
   04150 mTOR signaling pathway
    100350803
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100350803
   04137 Mitophagy - animal
    100350803
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    100350803
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100350803
   05014 Amyotrophic lateral sclerosis
    100350803
   05016 Huntington disease
    100350803
   05017 Spinocerebellar ataxia
    100350803
   05022 Pathways of neurodegeneration - multiple diseases
    100350803
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100350803
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ocu04131]
    100350803
   03029 Mitochondrial biogenesis [BR:ocu03029]
    100350803
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100350803
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: Other
  ULK family [OT]
   100350803
Membrane trafficking [BR:ocu04131]
 Autophagy
  Autophagosome formation proteins
   ULK complex
    100350803
Mitochondrial biogenesis [BR:ocu03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    100350803
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ATG1-like_MIT2 ATG1-like_MIT1 Kdo ABC1 RIO1 Pkinase_fungal Kinase-like
Other DBs
NCBI-GeneID: 100350803
NCBI-ProteinID: XP_008251411
Ensembl: ENSOCUG00000015070
Position
Unknown
AA seq 1049 aa
MEPGRGGIETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL
GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTIRLFLQ
QIAGAMRLLHSKGIIHRDLKPQNILLANPGGRRANPSNIRVKIADFGFARYLQSNMMAAT
LCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLV
PTIPRETSAPLRQLLLALLQRNHKERMDFDEFFHHPFLDASASVKKSPPVPVPSYPSSGS
GSSSSSSCTSHLASPPSLGEMPPLQKTLTSPAAAAGFLHGSRDSGGSSKDSCDTDDFVMV
PAQFPGDLVAEAAGAKPLPDSLLYSGSSLVASAGLDSHGRTPSPSPPCSSTPSPSGRAGP
FSSSRCGASVPIPVPTQVHNYQRIEQNLQSPTQHQAPRSSSRSPAIRRSGSTSPLSLARA
SPSPPAHTDGALLARKLSLGGGRPYTPSPQVGAIPERLGWSRAPSPQAAEMRTGRSPRPG
SSAPEHSPRSTGLGYRLHSAPNLSDLHVVRPKLPKPPTDPLGVAFSPPQASPPQPSHGLQ
SCRPLRGSPKLPDFLQRNPLPPILGSPTKAMSSFDFPKTPSSQNLLTLLARQGMVMTPPR
NRTLPDLSEVGPFQGQQLGPGLRPTEDARGPVGRSFSTSRLTDLLLRAAFGTQASDWGST
DSLQEKPMDTAPSAGFGGNLHPGARAGGASSPAPVVFTVGSPPSGTTPPQGPRTAAFSVG
PAGSSTRPLVVGACGEAAPELPAPGHCCSFADPIAANLEGAVTFEAPDLPEETLMEQEHT
EILHSLRFTLVFVQHVLEIAALKGSASEAAAAPESQLQESVVADQISLLSREWGFAEQLV
LYLKVAELLSAGLQTAIDQIRAGKLCLSSTVKQVVRKLNALYKASVVSCQGLRLRLQRFF
LDKQRLLDRVHSITAEKLIFSHAVQMVQSAALDEMFQHHEGCVPRYHKALLLLEGLQQLL
SDQADIENIAKCKLCIERRLSALLTGIGA
NT seq 3150 nt   +upstreamnt  +downstreamnt
atggagcccggccgcggcggcatcgagaccgtgggcaagttcgagttctcccgcaaggac
ctgatcggccacggcgccttcgcggtggtgttcaagggccgccaccgggagaagcatgac
ctagaggtcgcagtcaagtgcattaacaagaagaacctagccaagtcccagacgctgttg
gggaaggagattaaaatcctaaaggaactgaaacacgaaaacattgtggcattatatgac
ttccaggaaatggccaactctgtctacctggtcatggagtactgtaacggcggggacctg
gctgactacctgcacaccatgcggacgctgagcgaggacaccatccggctgttcctgcag
cagatcgccggcgccatgcggctgctgcacagcaaaggcatcatccaccgcgacctgaag
ccccagaacatcctgctggccaaccccggagggcgccgcgccaaccccagcaacatccgc
gtcaagattgctgacttcgggttcgcgcgctacctccagagcaacatgatggcggccacg
ctctgcggctcccccatgtacatggcccccgaggtgatcatgtcccagcactacgatggg
aaggcagacctgtggagtatcggcaccatcgtttaccagtgcctgacagggaaggcgccc
ttccaggccagcagcccccaggacctccgcctgttctacgagaagaacaagacgctggtc
cccaccatcccccgcgagacctcagcccccctcaggcagctgctcctggccctgctgcag
cgcaaccataaagaacgcatggacttcgatgagttcttccatcaccctttcctcgacgcc
agcgcctcggtcaagaagtccccgcccgtgcctgtgccctcgtacccaagctcagggtct
ggcagcagctccagcagcagctgcacctcccatctggcttccccaccgtccctgggggag
atgcccccgttacagaagacgctcacctccccggctgcggccgccggcttcctgcatggc
tcgcgcgactcagggggcagcagcaaggactcctgcgacacagacgacttcgtcatggtc
cccgcccagtttccaggtgacctggtggctgaggcggctggtgccaagcccctgccggac
agcctgctgtacagtgggagctcgctggtggcctctgctggcctggacagccacggccgg
actccttctccatcccccccatgcagtagcacccccagcccctcaggccgggctggcccg
ttctccagctccaggtgtggtgcctctgtccccatcccagtgcctacgcaggtgcacaac
taccagcgcatcgagcagaacctgcagtcccccacccagcaccaggcgccccggtcctcc
tccaggtctcctgccattcgcaggtcaggaagcaccagccctctgagcttggccagggcc
agcccctcgcccccagcccacaccgacggagccctcctggccaggaagttgtccctgggt
gggggccgaccctacacaccgtctccacaagttggagccatccctgagcggctgggctgg
agcagggctccctccccacaagcagctgagatgcggactggcaggtccccgcgtccaggc
tcctctgctcccgagcactcgccccgctccaccggcctgggctatcgcctgcacagcgcc
cccaacctgtctgacctgcatgtcgtccgccccaagctgcccaagccacccacggacccg
ctgggcgtggccttcagccccccacaggccagccctccccagccgtcccatggtctgcag
tcctgccggcccctgcgcggctcacccaagctgcccgacttcctgcagaggaaccccttg
ccccccatcctgggctcccccaccaaggccatgtcctccttcgacttccccaagaccccc
agctcccagaacctgctgaccctcctggcccggcagggcatggtgatgacgcccccacgg
aaccggacactgcccgacctctcagaggtggggcccttccaggggcagcagctgggccct
ggcctgcggcccacagaggatgccaggggccccgtcggccggtccttcagcaccagccgc
ctcaccgacctgctgctcagggcagcatttgggacgcaggcctcggactggggcagcaca
gacagcctgcaggagaagcccatggacactgcgccctctgctggcttcggagggaacctg
cacccaggagctcgtgctggcggggccagcagccccgcgccagtggtattcaccgtgggc
tctcccccaagtgggaccacgccgccccagggcccacgcactgcagccttctcagtgggc
cctgccggctcctccacgcgccccctggtggtcggggcctgcggcgaggctgctccagag
ctgccggcccctggccactgctgcagctttgccgaccccattgccgccaacctggagggg
gctgtgacctttgaagcccccgacctccctgaggagacgctcatggagcaagagcacacg
gagatcctgcacagcctgcgcttcacgctcgtcttcgtccagcacgtcctggagatcgcc
gccctgaagggcagcgccagcgaggcggccgcggcccccgagtcccagctgcaggagagc
gtggtggccgaccagatcagcctgctgagccgcgagtggggcttcgcagagcagctggtg
ttgtacctgaaggtggccgagctgttgtctgctggcctgcagacagccatagaccagatc
cgggccggcaagctctgcctgtcgtctaccgtgaagcaagtggtgcgcaagctgaacgcg
ctgtacaaggccagcgtggtgtcctgccagggcctgcgcctgcgcctgcagcgcttcttc
ctggacaagcagcgactgctggaccgcgtccacagcatcaccgccgagaagctcatcttc
agccacgccgtgcagatggtgcagtcggccgccctggacgagatgttccagcaccatgag
ggctgcgtgccacgctaccacaaggccctgctgctcctggaggggctgcagcagctgctg
tctgaccaggccgacattgagaacatcgccaagtgcaaactgtgcatcgagcggagactc
tcggctctgctgaccggcattggtgcctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG ORTHOLOGY (1)   
   RefGene (36)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (9)   
   Pfam (9)   
All databases (81)   

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