KEGG   Oryctolagus cuniculus (rabbit): 100353573
Entry
100353573         CDS       T03373                                 
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF1 isoform X1
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04120  Ubiquitin mediated proteolysis
ocu04137  Mitophagy - animal
ocu04144  Endocytosis
ocu04340  Hedgehog signaling pathway
ocu04350  TGF-beta signaling pathway
ocu04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    100353573
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    100353573
   04350 TGF-beta signaling pathway
    100353573
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100353573
   04137 Mitophagy - animal
    100353573
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100353573
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ocu04131]
    100353573
   04121 Ubiquitin system [BR:ocu04121]
    100353573
   03029 Mitochondrial biogenesis [BR:ocu03029]
    100353573
Enzymes [BR:ocu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     100353573
Membrane trafficking [BR:ocu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    100353573
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    100353573
Ubiquitin system [BR:ocu04121]
 Ubiquitin ligases (E3)
  HECT type E3
   100353573
Mitochondrial biogenesis [BR:ocu03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    100353573
SSDB
Motif
Pfam: HECT WW C2
Other DBs
NCBI-GeneID: 100353573
NCBI-ProteinID: XP_051703729
Ensembl: ENSOCUG00000016326
Position
6:28606395..28714614
AA seq 757 aa
MSNPGTRRSGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP
KWNQHYDLYVGKSDSITISVWNHKKIHKKQGAGFLGCVRLLSNAVSRLKDTGYQRLDLCK
LNPSDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEGTVYEDSGPGRPLSCFMEEPA
PYTDGPGAAGGGGNCRFVESPSQDQRLQAQRLRTPEVRGSLQTPQNRPHGHQSPELPEGY
EQRTTVQGQVYFLHTQTGVSTWHDPRVPSPLGTIPGGDEAFLYEFLLQGHTAEPRDLNSV
NCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCRLKEPSQPLPLPS
EGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMR
PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNSYMLQINPDSS
INPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLV
WILENDITPVLDHTFCVEHNAFGRLLQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGI
EAQFLALQKGFSELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVR
WFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLP
KAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE
NT seq 2274 nt   +upstreamnt  +downstreamnt
atgtcgaaccccgggacgcgcagaagcggctccagcatcaagatccgtctgacagtgtta
tgtgccaagaaccttgcaaagaaggacttcttccggctcccggacccctttgcgaagatc
gtcgtggacgggtctggccagtgccactccaccgacaccgtgaaaaacacgctggaccca
aagtggaaccagcattacgacctgtacgtggggaaatcggactccataaccatcagcgtg
tggaaccacaagaagattcacaagaagcagggcgccggcttcctgggctgtgtgcggctg
ctctccaacgccgtcagccggctgaaagacaccggatatcagcgtttggatctatgcaaa
ctaaatccctcggacactgacgcagttcgtggccaaatagtggtcagtttacagacacga
gacaggataggcaccggcgggtccgtggtagactgcaggggactactagaaaatgaagga
accgtgtacgaagactcggggcctgggaggccgctcagctgcttcatggaggagccagcc
ccttacacggatggccctggagccgccggcggcggcgggaactgcaggttcgtggaatcc
ccgagtcaagatcagagacttcaggcccaacggctgcggactcccgaggtccgaggatcg
ctccaaacgccacagaaccgaccccacggccaccagtccccggaactgcccgaaggctac
gagcaaagaaccacagtgcaggggcaagtttactttctgcacacacagaccggagttagc
acgtggcacgacccccgggtacccagtcccttggggaccattcctgggggagatgaagct
tttctatacgagttccttctccaaggccatacagctgagcccagagacctcaacagcgtg
aactgtgatgagctcggcccgctgccccccggctgggaagtcaggagcacggtttcgggc
aggatctacttcgtcgaccacaataaccgcaccacgcagttcacggacccgaggctgcac
cacatcatgaatcaccagtgccggctgaaggagcccagccagcccctgcccttgcccagc
gaaggctcggtggaggacgaggagctccctgcccagaggtacgaacgcgacctcgtccag
aagctcaaagtcctcaggcacgagctgtcgctgcagcagccgcaggccggccactgccgc
atcgaggtttcccgagaagaaatatttgaggagtcttaccgccagataatgaagatgcgc
ccgaaggacttgaagaagcggctgatggtgaagttccgtggggaggagggcctggattac
ggcggcgtggcgagggagtggctttacttgctgtgccacgagatgctgaacccctactac
gggctcttccagtactccacggacaacagctacatgctgcagatcaaccccgactcctcc
atcaaccccgaccacttgtcttacttccacttcgtgggtcggatcatgggcctggccgtg
ttccacgggcactacatcaacgggggcttcacggtccccttctacaagcagctgctgggg
aagcccatccagctgtcggacctggagtcggtggacccggagctgcacaaaagcctggtg
tggatcctggagaatgacatcacgccggtgctggaccacacgttctgcgtggagcacaat
gctttcgggcggctccttcagcatgaactcaagcccaacggcaggaacgtgcccgtcacg
gaggagaacaagaaagaatacgtccggctgtacgtgaactggcggttcatgcgtgggatt
gaggcccagttcctagccctgcagaagggcttcagcgagctcatccctcagcacctcctg
aagccgttcgaccagaaggagctggagttgatcataggcggcctggacaagatcgacttg
aacgactggaagtcgaacacgcggctcaagcactgcgtggccgacagcaacatcgtgcgc
tggttctggcaggcggtggagaccttcgacgaggagcggagggcccggctgctgcagttc
gtgacggggtccacgcgcgtgccgctccaaggcttcaaggccttgcaaggttccacaggc
gccgcagggccccggctgttcaccatccacctgatagacgccaacacagacaacctcccc
aaagcgcatacctgctttaaccggatcgacatccccccgtatgagtcctacgagaagctc
tacgagaagctgctgaccgcggtggaggagacctgtgggtttgccgtggagtga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   RefSeq(pep) (6)   
DNA sequence (12)   
   RefSeq(nuc) (6)   
   GenBank (3)   
   EMBL (3)   
Protein domain (3)   
   Pfam (3)   
All databases (47)   

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