KEGG   Orcinus orca (killer whale): 101270049
Entry
101270049         CDS       T05247                                 
Symbol
CBL
Name
(RefSeq) E3 ubiquitin-protein ligase CBL isoform X1
  KO
K04707  E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04012  ErbB signaling pathway
oor04120  Ubiquitin mediated proteolysis
oor04144  Endocytosis
oor04910  Insulin signaling pathway
oor05100  Bacterial invasion of epithelial cells
oor05200  Pathways in cancer
oor05205  Proteoglycans in cancer
oor05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:oor00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101270049 (CBL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101270049 (CBL)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101270049 (CBL)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101270049 (CBL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101270049 (CBL)
   05205 Proteoglycans in cancer
    101270049 (CBL)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    101270049 (CBL)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    101270049 (CBL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oor04131]
    101270049 (CBL)
   04121 Ubiquitin system [BR:oor04121]
    101270049 (CBL)
Enzymes [BR:oor01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     101270049 (CBL)
Membrane trafficking [BR:oor04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    101270049 (CBL)
Ubiquitin system [BR:oor04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   CBL proteins
    101270049 (CBL)
SSDB
Motif
Pfam: Cbl_N Cbl_N3 Cbl_N2 zf-C3HC4 zf-C3HC4_3 Prok-RING_4 zf-RING_2 UBA zf-C3HC4_2 zf-RING_UBOX zf-RING_5 zf-C3HC4_4
Other DBs
NCBI-GeneID: 101270049
NCBI-ProteinID: XP_004273348
Position
8:95694223..95783112
AA seq 910 aa
MAGNVKKSSGAGGGGGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCW
KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFME
NLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFR
ITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFE
FDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRL
GQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDH
IKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCR
CEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDSLFMMKELAGAKVER
PPSPFSMAPQASLPPVPPRLDLLQQRISIPSSASGLGTASKAPSGSLHKDKPLPIPPTLR
DLPPPPPPDRPYSGGAETRPQRRPLPCTPGDCPSRDKLPPVPSGRAGEASWLPRPIPKVP
VVAPNPSDPWTGRELTNRHSLPFSLPSQMEPRTDVPRLGSTFSLDTSMNTNSSPLAGPEC
EHPKIKPSASANAIYSLAARPLPVPKPPPGEQCKSEEDTEYMTPSSRPVGLQKPEVKWPL
ETTQSSRACDCNQQIDSCTYEAMYNIQSQAAPSVTESGTFGEGNLAAAHANTGPEESENE
DDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLEGDPTTNFAEGSQVPERPPKPFPRR
INSERKAGSCQQSTAATSPQLSSEIESLMSQGYSYQDIQKALVIAHNNIEMAKNILREFV
SISSPAHVAT
NT seq 2733 nt   +upstreamnt  +downstreamnt
atggccggcaatgtgaaaaagagctctggggccgggggcggcggcggctccgggggttcg
ggctcgggaggcctgatcgggctcatgaaggacgccttccagccgcaccaccaccaccac
caccacctcagcccccaccctccgggcaccgtggacaagaagatggtggagaagtgctgg
aagctcatggacaaggtggtgcggttgtgtcagaacccaaagctggcgctaaagaatagc
ccaccttatatcttagacctgctgccagacacctaccagcatctccgcactatcttgtca
agatatgaggggaagatggagacccttggagaaaatgagtattttagggtgttcatggag
aatttgatgaagaaaactaagcagaccataagcctcttcaaggaggggaaagaaagaatg
tatgaggagaattctcagcctaggcgaaacctaaccaaactgtccctgatcttcagccac
atgctggcagaactaaaaggaatctttccaagtggactctttcaaggagacacatttcgg
attactaaagcagatgctgcagaattttggaggaaagcttttggggaaaagacaatagta
ccttggaagagcttcagacaggcccttcatgaagtacatcccatcagttctgggctggag
gccatggctctgaaatccactattgatctgacctgcaatgattatatttcagtgtttgaa
ttcgacatctttacacgactctttcagccctggtcttctttgctcaggaactggaacagt
cttgctgtaactcatcctggttacatggctttcctgacatatgatgaagtgaaagctcgg
ctccagaaattcattcacaaacctggcagttacattttccggctgagctgtactcgtctg
ggtcagtgggctattgggtatgtcactgctgatgggaacattctccagacaattcctcac
aataaacctctcttccaagcgctgattgatggcttcagggaaggcttctatttgtttcct
gatggacggaatcagaatccagacctgacaggcttatgtgaaccaactccccaagaccac
atcaaagtgacccaggaacaatatgaattatactgtgagatgggctccacattccaactg
tgtaaaatatgtgctgaaaatgataaagatgtaaagattgagccctgtggacacctcatg
tgcacatcctgtctaacatcctggcaggaatcagaaggccagggctgtcccttctgccga
tgtgaaattaaaggtactgagcccattgtggtcgatccctttgatcctagaggaagtggc
agcctgctgaggcaaggagcagagggagctccctccccaaattatgatgatgatgacgat
gaacgagctgatgattctctcttcatgatgaaggaattggctggtgccaaggtggaacga
cctccttctccattctccatggccccacaagcttcccttcccccagtgccaccacgactt
gaccttctacaacagcgaatatctattccttcaagtgcttctggtcttggaactgcttct
aaggctccttctggctcccttcataaggacaaaccattaccaatacctcccactcttcga
gatcttccaccaccaccccctccagaccggccatattctggtggagcggaaacacggcct
cagagacgccccttgccatgtacaccaggcgactgtccgtccagagacaaactgccccct
gtcccctctggccgtgctggagaagcatcatggctgcctcggccaatccccaaagtacca
gtagttgcgccaaaccctagtgacccctggacagggagagaattaaccaaccggcactca
cttccattttccttgccctcacaaatggaacccagaaccgatgtgcctaggcttggaagc
acattcagtctggatacctccatgaatacgaatagcagcccgttagcaggtccagagtgt
gagcatcccaaaatcaaaccttctgcatctgccaatgccatttattctctggctgccaga
cctcttcctgtgccaaagccgccacctggggagcagtgtaaaagtgaggaggacacagag
tatatgactccttcctctaggcctgtgggacttcaaaagccagaagtgaagtggcctctg
gagacaacccagagttcacgagcctgtgattgtaaccagcagatcgatagttgtacatac
gaagcaatgtataatattcagtcccaggcggcaccgtctgtcacagagagcggcaccttt
ggtgaagggaatttggctgcagcccatgccaacactggccctgaggaatcagaaaatgaa
gacgacgggtacgatgtccccaagccacctgtgcccgcagtgctggcccgccgcacgctc
tctgacatctccaacgccagctcctccttcggctggctgtctctggaaggtgatcccaca
acgaacttcgctgagggttcccaagttcctgagaggccacccaaaccgttccctcggaga
atcaactctgaacgaaaagcaggtagctgtcagcaaagcaccgccgccacctcaccgcag
ctctccagcgagattgagagcctcatgagtcagggatactcctaccaggacattcagaaa
gctctggtcattgcccacaacaatattgaaatggccaaaaacatcctccgggaatttgtt
tctatttcttctcctgcccatgtagccacctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (12)   
   Pfam (12)   
All databases (49)   

Download RDF
DBGET integrated database retrieval system