KEGG T05247: 101270798

Orcinus orca (killer whale): 101270798

Entry

101270798         CDS       T05247

Symbol

RRM2

Name

(RefSeq) ribonucleoside-diphosphate reductase subunit M2 isoform X4

K10808

ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]

Organism

oor Orcinus orca (killer whale)

Pathway

oor00230

Purine metabolism

oor00240

Pyrimidine metabolism

oor00480

Glutathione metabolism

oor00983

Drug metabolism - other enzymes

oor01100

Metabolic pathways

oor01232

Nucleotide metabolism

oor04115

p53 signaling pathway

Module

oor_M00053

Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP

oor_M00938

Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP

Brite

KEGG Orthology (KO) [BR:oor00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101270798 (RRM2)
   00240 Pyrimidine metabolism
    101270798 (RRM2)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101270798 (RRM2)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    101270798 (RRM2)
09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    101270798 (RRM2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:oor03400]
    101270798 (RRM2)
Enzymes [BR:oor01000]
1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     101270798 (RRM2)
DNA repair and recombination proteins [BR:oor03400]
Eukaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    101270798 (RRM2)

SSDB

Motif

Pfam:

Ribonuc_red_sm

Other DBs

NCBI-GeneID:

101270798

NCBI-ProteinID:

XP_004274938

Position

13:complement(84477399..84533660)

AA seq 392 aa
MLSVRVPLATIADPQQQHPLQLSPMKGLSLADKENTPPSLSGTRVLASKTARRIFQEPAE
PNPKLSAPSVEEEPLLKENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE
ALKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYS
LLIDTYIKDSKEREFLFNAIETMPCVKKKADWALCWIGDKEATYGERVVAFAAVEGIFFS
GSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLLHKPSEQRVKDIIVNAV
RIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEG
KTNFFEKRVGEYQRMGVMSSPTENSFTLDADF

NT seq 1179 nt +upstreamnt +downstreamnt
atgctctccgtccgtgtccctctcgccaccatcgctgacccgcagcagcagcatcccctc
cagctctcgcccatgaaggggctcagcctggcggacaaggagaacactcccccgtccctc
agcgggacccgcgtgctggccagcaagaccgcgaggaggatcttccaggagcccgccgag
ccaaaccctaagctatctgcccccagtgtggaggaggaaccacttctgaaagaaaacccc
cgccgctttgtcatctttcctatcgaataccatgatatctggcagatgtataagaaagct
gaggcttccttttggacagctgaggaggtggacctttccaaagacattcagcactgggaa
gccctgaagcctgaggagagatatttcatttcgcatgttctggctttctttgcagcaagt
gatggcatagtaaatgaaaacttggtggagcggtttagccaagaagttcagattacggaa
gcccgttgtttctatggcttccaaattgccatggaaaacatacattctgaaatgtatagt
ctcctcattgacacttacattaaagattccaaagaaagggaatttctcttcaacgccatt
gagacaatgccttgtgtaaagaagaaggcagattgggccttgtgctggattggggacaaa
gaggctacgtatggagaacgtgttgtagcctttgctgcagtggaaggaatcttcttttct
ggttcttttgcatcgatattctggctcaaaaaacgaggactgatgcctggcctcacattt
tccaatgaacttattagcagagacgagggtttacactgtgactttgcctgcctgatgttc
aaacacctgctacacaaaccttcggagcagagagtcaaagatatcatcgtcaatgcagtt
aggatagaacaggagttcctcacggaggccctgccagtgaagctcattggaatgaattgc
actttgatgaagcagtacatcgaattcgtggcagacagactcatgctggagctgggtttt
agcaaggttttcagagtagaaaatccatttgactttatggagaatatttcactggaaggg
aagactaacttctttgagaagagagtaggcgagtatcagaggatgggagtgatgtccagt
ccgacagagaattcctttaccttggatgctgacttctaa

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