KEGG   Orcinus orca (killer whale): 101271879
Entry
101271879         CDS       T05247                                 
Symbol
CAMK2A
Name
(RefSeq) calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
  KO
K04515  calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04012  ErbB signaling pathway
oor04020  Calcium signaling pathway
oor04024  cAMP signaling pathway
oor04066  HIF-1 signaling pathway
oor04114  Oocyte meiosis
oor04148  Efferocytosis
oor04217  Necroptosis
oor04261  Adrenergic signaling in cardiomyocytes
oor04310  Wnt signaling pathway
oor04360  Axon guidance
oor04713  Circadian entrainment
oor04720  Long-term potentiation
oor04722  Neurotrophin signaling pathway
oor04725  Cholinergic synapse
oor04728  Dopaminergic synapse
oor04740  Olfactory transduction
oor04750  Inflammatory mediator regulation of TRP channels
oor04911  Insulin secretion
oor04912  GnRH signaling pathway
oor04916  Melanogenesis
oor04921  Oxytocin signaling pathway
oor04922  Glucagon signaling pathway
oor04925  Aldosterone synthesis and secretion
oor04934  Cushing syndrome
oor04971  Gastric acid secretion
oor05012  Parkinson disease
oor05022  Pathways of neurodegeneration - multiple diseases
oor05031  Amphetamine addiction
oor05152  Tuberculosis
oor05200  Pathways in cancer
oor05205  Proteoglycans in cancer
oor05214  Glioma
oor05415  Diabetic cardiomyopathy
oor05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101271879 (CAMK2A)
   04310 Wnt signaling pathway
    101271879 (CAMK2A)
   04066 HIF-1 signaling pathway
    101271879 (CAMK2A)
   04020 Calcium signaling pathway
    101271879 (CAMK2A)
   04024 cAMP signaling pathway
    101271879 (CAMK2A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101271879 (CAMK2A)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101271879 (CAMK2A)
   04217 Necroptosis
    101271879 (CAMK2A)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    101271879 (CAMK2A)
   04922 Glucagon signaling pathway
    101271879 (CAMK2A)
   04912 GnRH signaling pathway
    101271879 (CAMK2A)
   04921 Oxytocin signaling pathway
    101271879 (CAMK2A)
   04916 Melanogenesis
    101271879 (CAMK2A)
   04925 Aldosterone synthesis and secretion
    101271879 (CAMK2A)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101271879 (CAMK2A)
  09154 Digestive system
   04971 Gastric acid secretion
    101271879 (CAMK2A)
  09156 Nervous system
   04725 Cholinergic synapse
    101271879 (CAMK2A)
   04728 Dopaminergic synapse
    101271879 (CAMK2A)
   04720 Long-term potentiation
    101271879 (CAMK2A)
   04722 Neurotrophin signaling pathway
    101271879 (CAMK2A)
  09157 Sensory system
   04740 Olfactory transduction
    101271879 (CAMK2A)
   04750 Inflammatory mediator regulation of TRP channels
    101271879 (CAMK2A)
  09158 Development and regeneration
   04360 Axon guidance
    101271879 (CAMK2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101271879 (CAMK2A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101271879 (CAMK2A)
   05205 Proteoglycans in cancer
    101271879 (CAMK2A)
  09162 Cancer: specific types
   05214 Glioma
    101271879 (CAMK2A)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    101271879 (CAMK2A)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    101271879 (CAMK2A)
   05022 Pathways of neurodegeneration - multiple diseases
    101271879 (CAMK2A)
  09165 Substance dependence
   05031 Amphetamine addiction
    101271879 (CAMK2A)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101271879 (CAMK2A)
   05415 Diabetic cardiomyopathy
    101271879 (CAMK2A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101271879 (CAMK2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oor01001]
    101271879 (CAMK2A)
Enzymes [BR:oor01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     101271879 (CAMK2A)
Protein kinases [BR:oor01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   101271879 (CAMK2A)
SSDB
Motif
Pfam: Pkinase CaMKII_AD PK_Tyr_Ser-Thr DUF4440 SnoaL_3 SnoaL_2 SnoaL_4 APH Kdo
Other DBs
NCBI-GeneID: 101271879
NCBI-ProteinID: XP_004280401
Position
3:58978487..59043091
AA seq 489 aa
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
VHTTILNPHIHLMGDEAACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIIHFHR
SGAPSVLPH
NT seq 1470 nt   +upstreamnt  +downstreamnt
atggccaccatcacctgcacccgcttcacggaagagtaccagctcttcgaggaactggga
aagggagccttctcagtggtgcgcaggtgtgtgaaggtgctggctggccaggaatatgct
gccaagatcatcaacactaagaagctctcggccagagaccaccagaagctggagcgtgaa
gcccgcatctgccgcctgctgaagcaccccaacattgtccggctccacgacagcatctcc
gaggagggacaccattacctgatctttgacctcgtcaccggcggggagctgtttgaagac
atcgtggcccgggagtattacagtgaggcagatgccagtcactgtatccagcagatcctg
gaggccgtgctgcactgccaccagatgggggtggtacaccgggacttgaagccggagaat
ctgttgcttgcctccaagctcaagggcgctgcagtgaagctggcggactttggcctggcc
atagaggtggagggggaacagcaggcatggtttgggttcgcaggaacacccggatacctc
tccccagaagtgctgcggaaggacccgtacgggaagcctgtggatctgtgggcctgtggg
gtcatcctgtacatcctgctggttgggtatcccccgttctgggatgaggaccagcaccgc
ctgtaccagcagatcaaagctggcgcctatgatttcccgtcaccagaatgggacaccgtc
accccggaagccaaggatctgatcaacaagatgctgaccatcaacccatccaaacgcatc
acggccgccgaggccctcaagcacccctggatctcgcaccggtccaccgtggcctcctgc
atgcacagacaggagaccgtggactgcctgaagaagttcaacgccaggagaaaactgaag
ggagctatcctcaccactatgctggccaccaggaacttctccggcgggaagagtggagga
aacaagaagaacgatggtgtgaagaaaagaaagtccagttccagcgttcagttaatggaa
tcttcagagagcaccaacaccaccattgaggatgaagacaccaaagtgcggaaacaagaa
attataaaagtgacagaacagctgattgaagccataagcaatggagattttgagtcctac
acgaagatgtgtgaccctgggatgacagccttcgaacccgaggccctagggaacctggtc
gagggcctggacttccatcgattctattttgaaaacctgtggtcccggaacagcaagcct
gtgcacaccaccatcctgaatccccacattcacctgatgggtgacgaggcggcctgcatc
gcctacatccgcatcacgcagtacctggatgcgggcggcatcccccgcacggcccagtcg
gaagagacccgcgtctggcaccgccgggatggcaaatggcagatcatccacttccacaga
tctggggcgccctccgtcctgccccactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (34)   
   KEGG PATHWAY (34)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (9)   
   Pfam (9)   
All databases (63)   

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