KEGG   Orcinus orca (killer whale): 101275708
Entry
101275708         CDS       T05247                                 
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
  KO
K18437  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00230  Purine metabolism
oor01100  Metabolic pathways
oor04927  Cortisol synthesis and secretion
oor04934  Cushing syndrome
oor05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101275708 (PDE8A)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    101275708 (PDE8A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    101275708 (PDE8A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101275708 (PDE8A)
Enzymes [BR:oor01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     101275708 (PDE8A)
SSDB
Motif
Pfam: PDEase_I PAS PAS_9 PDE8 PAS_4 PAS_3 Response_reg PAS_8 Band_7_C DUF5894
Other DBs
NCBI-GeneID: 101275708
NCBI-ProteinID: XP_012391637
Position
2:complement(60729961..60867218)
AA seq 840 aa
MGCAQSIHASESRVVYHGGNEAEDAPGPAAPPLQPGGPRLPPGQTTAASARSCGSSLVES
ELSIGSGSSIGSAVAVADIQFGPMRFHPDQLQVLLVFPKEDKQCNGFCRACEKAGFKCTV
IKEAQTALACFLDKHHDIIIIDHRNPQQLDGEVLCRSIRSSELSENTVIVGVVRRAVREE
SSVMSLIEAGFTRRYVENPSAMACYNELLQMEFGLVRPQLKLRACNSMFTALEKSQEAIE
ITSEDHIVQYANPAFETTMGYESGELIGKDLAEVPVNEKKADLLDTINSCIRIGKEWQGI
CSAKEKNGDNVQQNVKILPVIGQGGKIRHYVSIVRACNGNNKATKIAECVQSDTHTDHQS
GKHNDRRKSSLDVRTAASRTGKVSSQRRRSSTARIHSMKIEAPITKAINIISAAQESSPM
PVTEALDRVLEILRTTELYSPQFDAKDDDPHAIDLVGGLMSDVFRRPSRNEYVLSTKNLQ
QASSSVITPTSLHDIPSQITQAMENEESWDFDIFELEAATHKRPLIYLGLKIFARFGVCE
VLKCSETTLRSWLQIIEANYHASNPYHNSTHSADVLHATAYFLCKERIKQTLDPLDEVTA
LIAATVHDLDHPGRTNSFLCNAGSELAILYNDTAVLERHHAALAFQLTTGDDKCNIFKNM
ERNDYRMLRQSIIDMVLATEMTKHFEHVNKFVNSINKPLAALEEDGETDKNQEAIITMLR
TPDNRSLIKRMLIKCADVSNPCRPLEQCIEWAARISEEYFSQTDEEKRQDLPVVMPVFDR
NTCSIPKSQISFIDYFITDMFAAWDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq 2523 nt   +upstreamnt  +downstreamnt
atgggctgtgcccagagcatccacgcttccgagagccgggttgtgtaccacggcggcaac
gaggccgaggacgcgccgggccccgcggcgccgccgttgcagcccggcgggccgcgcctc
ccacccggccagacgacggctgcctcggcccggtcctgtggctccagcctcgtggagtcc
gagctaagcatcggcagcggcagcagcatcggcagcgcggtagcagtagctgatatacag
tttggccccatgagatttcatccagatcagctccaggtacttttagtgtttcccaaagaa
gataagcagtgtaatggattctgtagggcatgtgaaaaagcagggtttaagtgtacagtt
atcaaggaggctcagacggcccttgcctgtttcctggacaaacatcatgacatcatcatc
attgaccacagaaatccccaacagctggacggggaggtgctgtgcaggtctatcagatca
tcagaactctcagaaaacacagttattgttggtgtagtacgcagggcggttagagaagag
tcatctgtaatgtccctcattgaggctggctttacaaggaggtatgtagaaaaccccagc
gccatggcctgttacaatgaactgctccagatggagtttggattggtgcgcccacagctg
aaactcagggcttgtaactcaatgttcactgcattagagaaaagtcaagaagcaattgaa
attacaagtgaagaccacattgtacagtatgcaaatccagcatttgaaacaacaatgggc
tatgagtcaggtgaattaatagggaaggatttagcagaagtgcctgtaaatgaaaaaaag
gctgatttgctcgatactataaattcatgcatcaggataggcaaggaatggcaaggaatt
tgctctgccaaagagaagaacggagataatgtacaacaaaatgtgaagatactacctgtc
atcgggcagggaggaaaaattagacactatgtgtccattgtcagagcgtgcaatggcaac
aataaggctacgaaaatagctgaatgtgttcagtctgacactcatacagatcatcagtca
ggcaaacataatgacaggaggaaaagctcactagatgtcagaactgctgcctctcgaaca
ggcaaagtttccagccagagacgacgctcctccacggcccggatacattccatgaagatc
gaggcgcccatcaccaaggcaatcaatatcatcagtgctgcccaggaaagcagtcccatg
cctgtgacagaagccttagatcgtgtgctggaaattctaagaaccactgaattatattca
ccacaattcgatgctaaggacgatgatcctcatgccatcgaccttgttgggggcttaatg
tctgacgtttttcgaagaccgtccaggaatgagtatgttctttcaacaaaaaaccttcag
caggcttccagcagtgtgatcacccccacctcccttcacgacatcccatcacagataact
caggccatggaaaatgaggaatcctgggactttgatatttttgaactggaggctgccact
cataaaaggcctttgatttatcttggtctcaaaatatttgctcgctttggagtctgtgaa
gtcttaaaatgctctgagacaacgctgagatcgtggctgcaaattatcgaagccaattat
catgcttctaacccctaccacaattctacacattctgccgacgtgcttcatgccactgcc
tattttctctgcaaggagaggataaagcaaactttagatccacttgatgaggtcactgcc
ctcattgcagccactgtccatgacctggaccatcccgggagaaccaactccttcctgtgc
aatgctgggagtgagctggccattctgtataacgacactgctgtgctcgagagacaccac
gcggccttggccttccagctgaccactggtgatgataaatgcaacatctttaaaaacatg
gagaggaatgactaccggatgctgcgccagagtattatcgacatggtcttagccacagaa
atgacaaagcactttgagcacgtcaacaaatttgtcaacagcatcaacaagcccttggca
gcattagaggaagatggggaaactgataaaaatcaagaagccataatcactatgctcaga
actccagacaaccgcagtttgatcaaacgaatgctgattaagtgtgctgatgtgtccaat
ccctgccgacccctggagcagtgcattgagtgggccgcacgtatctcagaagaatatttt
tctcagactgatgaagagaagcgacaggacttgcctgtggtgatgccagtttttgacaga
aatacctgcagcatccccaaatcccaaatctctttcattgactacttcatcacagacatg
tttgctgcttgggacgcctttgtagacctgcctgagttaatgcagcatcttgacaacaat
tttaaatactggaagggactggacgaaatgaagctgcggagcctccgcccacctcctgaa
tag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (10)   
   Pfam (10)   
All databases (40)   

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