KEGG T05247: 101276233

Orcinus orca (killer whale): 101276233

Entry

101276233         CDS       T05247

Symbol

RPS6KA1

Name

(RefSeq) ribosomal protein S6 kinase alpha-1 isoform X2

K04373

ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]

Organism

oor Orcinus orca (killer whale)

Pathway

oor04010

MAPK signaling pathway

oor04114

Oocyte meiosis

oor04150

mTOR signaling pathway

oor04714

Thermogenesis

oor04720

Long-term potentiation

oor04722

Neurotrophin signaling pathway

oor04914

Progesterone-mediated oocyte maturation

oor04931

Insulin resistance

oor05135

Yersinia infection

oor05207

Chemical carcinogenesis - receptor activation

Brite

KEGG Orthology (KO) [BR:oor00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101276233 (RPS6KA1)
   04150 mTOR signaling pathway
    101276233 (RPS6KA1)
09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101276233 (RPS6KA1)
09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    101276233 (RPS6KA1)
  09156 Nervous system
   04720 Long-term potentiation
    101276233 (RPS6KA1)
   04722 Neurotrophin signaling pathway
    101276233 (RPS6KA1)
  09159 Environmental adaptation
   04714 Thermogenesis
    101276233 (RPS6KA1)
09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    101276233 (RPS6KA1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101276233 (RPS6KA1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101276233 (RPS6KA1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oor01001]
    101276233 (RPS6KA1)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:oor03019]
    101276233 (RPS6KA1)
Enzymes [BR:oor01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101276233 (RPS6KA1)
Protein kinases [BR:oor01001]
Serine/threonine kinases: AGC group
  RSK family [OT]
   101276233 (RPS6KA1)
Messenger RNA biogenesis [BR:oor03019]
Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     101276233 (RPS6KA1)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Kinase-like Kdo ABC1 Pkinase_fungal Pkinase_C Haspin_kinase YrbL-PhoP_reg

Other DBs

NCBI-GeneID:

101276233

NCBI-ProteinID:

XP_004266684

Position

1:complement(192068184..192104285)

AA seq 746 aa
MERDPKLPRLRLWALLPWLPRKQRPRISQTSLPAPGPGPGPGPRRDSDEDVLKEISITHH
VKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRT
KMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA
ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM
APEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEA
QSLLRSLFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTF
YFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRATQAPLHSVVQQLHG
KNLVFSDGYVVKETIGVGSYSECKRCVHKATTMEYAVKVIDKSKRDPSEEIEILLRYGQH
PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ
GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ
GYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSDTAK
DLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQLSHQDLQTVKGAMAATYSALNSSK
PTPQLKPIESSILAQRRVRKLPSTTL

NT seq 2241 nt +upstreamnt +downstreamnt
atggagcgggatcccaagctgccccgtctgcggctctgggccctgctcccctggctgccc
aggaagcagcggcccaggatcagccagacttctctgcctgcccctggccctggccctggc
cccggccccaggcgggattcggatgaagacgtcctcaaggagatctccatcacgcaccat
gtcaaggctggctccgagaaggccgacccatcccactttgagctcctcaaggttctgggc
caggggtcctttggcaaagtcttcctggtgcggaaggtcacccggcctgacagtgggcac
ctgtatgccatgaaggtactaaagaaggcgacactgaaagtgcgtgaccgcgttcggacc
aagatggagagagacatcctggctgatgtaaaccatccgtttgtggtgaagctgcactac
gccttccagactgagggcaagctctaccttattctggacttcctgcgtggcggagacctc
ttcacacggctctctaaagaggttatgttcacggaggaggatgtgaaattttacctggcc
gagctggctttgggcctggaccacctgcacagcctgggcatcatctacagagacctgaag
cctgagaacatccttctggatgaggaaggccacatcaaactcactgacttcggcttgagc
aaggaggccattgaccacgagaagaaggcctattccttctgtgggacggtggagtacatg
gcccccgaggtcgtcaaccgccagggccacacccacagtgcagactggtggtcctatggg
gtgctgatgtttgagatgctgacgggctccctgcccttccaggggaaggaccggaaggag
accatgacactgattctgaaggcaaagctaggcatgccccagtttctgagcacggaagcc
cagagcctcctgcggtccctgttcaagcggaatcctgccaaccggctcggctccggccct
gatggggcagaggaaatcaagcggcatgtcttctactccaccattgactggaataagctg
taccggcgcgagatcaagccacccttcaagccggctgtggcacaacccgatgacaccttc
tactttgacactgagttcacatcccgcacgcccaaggactccccaggcatcccccccagc
gctggtgcccatcagctgttccgtggcttcagcttcgtggccactggcctgatggaggac
gacggcaagcctcgggccacgcaggcgcccctgcactcggtggtacagcaactacatgga
aagaacctggtttttagcgacggctatgtggtaaaagagacgatcggtgtgggctcctac
tccgagtgcaagcgctgtgtccacaaggccaccaccatggagtatgctgtcaaggtcatc
gacaagagcaagcgagatccctcggaagagattgagattcttctgcggtacgggcagcac
cccaacatcatcactctgaaagatgtgtacgatgatggcaaacacgtgtacctggtgaca
gagctgatgcggggaggggagctgctggataagatcctacggcagaaattcttctcagag
cgtgaggccagcttcgtcctgcataccatcggcaagaccgtggagtatctgcactcccag
ggggttgtgcacagggacctcaagcccagcaacatcctgtatgtggacgagtctgggaac
cctgagtgcctgcgcatctgcgactttggctttgccaagcagctgcgggctgagaacggg
cttctcatgacaccttgctacaccgccaacttcgtggcgccggaggtactgaagcgccag
ggctatgacgagggctgcgacatctggagcctgggcattctgctgtacaccatgctggcg
ggatacactccatttgccaatggacccagtgacacaccagaggaaatcctgacccggatc
ggcagtgggaagttcaccctcagcgggggaaattggaacacggtttcagacacagccaag
gacctggtatccaagatgctgcatgtggacccgcaccagcgcctcacagctaagcaggtc
ctgcagcacccgtggatcacccagaaagacaagctcccccagagccagctatcccaccag
gacctacagactgtgaagggagccatggcagcgacatactctgcgctcaacagctccaag
cccacccctcagctgaagcccatcgagtcgtctatcctggcccagcggcgggtgaggaag
ctgccatcgaccaccctgtga

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