KEGG   Orcinus orca (killer whale): 101279717
Entry
101279717         CDS       T05247                                 
Symbol
ARHGEF1
Name
(RefSeq) rho guanine nucleotide exchange factor 1 isoform X1
  KO
K12330  Rho guanine nucleotide exchange factor 1
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04270  Vascular smooth muscle contraction
oor04611  Platelet activation
oor04810  Regulation of actin cytoskeleton
oor04928  Parathyroid hormone synthesis, secretion and action
oor05135  Yersinia infection
oor05163  Human cytomegalovirus infection
oor05200  Pathways in cancer
oor05205  Proteoglycans in cancer
oor05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oor00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101279717 (ARHGEF1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101279717 (ARHGEF1)
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    101279717 (ARHGEF1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101279717 (ARHGEF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101279717 (ARHGEF1)
   05205 Proteoglycans in cancer
    101279717 (ARHGEF1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101279717 (ARHGEF1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101279717 (ARHGEF1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101279717 (ARHGEF1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oor04131]
    101279717 (ARHGEF1)
Membrane trafficking [BR:oor04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    101279717 (ARHGEF1)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PH_13 HA Syntaxin_2
Other DBs
NCBI-GeneID: 101279717
NCBI-ProteinID: XP_033286747
Position
20:complement(47924996..47944117)
AA seq 969 aa
MEAEDVARGAAPGPPRPGLVPISIIGAEDEDFENELKTNPEEQNNQYQSLDQVKRHPAHL
MALLQHVAMQFEPGPLLCCLHADMLGSLGPKEAKKAFGDFCHSFLDKCAILRVTVPPTVA
FELDRTRPDLLSEDVQRHFVQEVVQTQQAAVSRQLEDFRSKKLMGMTPWEQELIQLGAWV
GRDRATYEARERHLAERQLAHLEDMQHTISNDEEKSAAVVSAITLYMRHLGVRTKSGDKK
SGRNFFRKKVMGNRRSEEPTKTKKGLSSFLDAARWNRGEPQAPDFRHLKVEADGEKPGLT
ERKGGLGVPSRDRNVGAPGQDTPGVSLHPLSGDSPDREPGVDALPELGDPPPQGPASLEP
AAPLESTEEGADTERLSGRLGRSESLRVSDRRRPSRGSLGAKGRGGGRSRSDVDMDPSSA
TAVLGPARRATPEPGDEGEPGRSGLELEPEEPPGWRELVPPGTLHSLPKSQVKRQEVISE
LLVTEAAHVRMLRVLYDLFYQPMADGGFFSLEELQNIFPSLDELIEVHSLFLDRLMKRRQ
DSGYLIEEIGDVLLAQFDGTEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEA
ESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPAEREKVELAAECCREILHHVN
QAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKA
VEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDHK
AFYVIFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPARTSRPKHRPSPSSTREP
LLSSSENGNGGREMPPADGRMERIFSALLPFCRPGPEGQLAAKALQKVLSLKQLLLPSEE
DSGVGPPLEGDGVPGGGPPSPVQPQEIREELLSLEETIKQLEEVEEEFCRLRLLLSPLGE
NTVPQSGCT
NT seq 2910 nt   +upstreamnt  +downstreamnt
atggaggccgaagacgtcgcccgaggggcggccccagggcccccccggcctggcctggtg
cccatcagcatcatcggggctgaggacgaggattttgagaatgagctgaagacgaacccc
gaggagcaaaacaaccagtaccagagcctggatcaggtgaagcggcacccggcccacctc
atggccctcctgcagcacgtggccatgcagttcgagccaggacccctgctctgctgcctg
cacgcggacatgctgggctcactgggccccaaggaggccaagaaggccttcggcgacttc
tgccacagcttcctggataagtgtgcgattctgcgggtgacggtccctcccaccgtggcc
tttgaacttgaccgcacgcggcccgatctcctctccgaggatgtccagcggcatttcgtg
caggaggtggtgcagacccagcaggcagccgtcagccggcagctggaggacttccgctcc
aagaagctcatgggcatgacaccctgggagcaggagctgatccagctgggggcctgggtt
gggcgggaccgcgccacctatgaggcccgggagcggcacctggccgagcggcagctggcc
cacctggaggacatgcaacacaccatctctaacgatgaggaaaagagtgctgctgtggtc
agtgccatcaccctgtacatgcgccacctcggggtgcggaccaagagtggagacaagaag
tcggggaggaatttcttccggaaaaaggtgatggggaaccggcggtcagaagagccgacc
aagaccaagaagggactgagcagcttcctggatgctgcccgctggaaccggggagagccc
caggccccagattttcgacacctcaaagttgaggctgatggtgagaagccaggccttaca
gaacgtaagggaggtctgggggtgccctcccgggaccggaatgtcggagcccctgggcag
gacacccccggagtttctctgcaccctctgtctggggacagccctgaccgggaaccaggt
gttgacgccctcccggagctgggggacccgcccccgcagggcccagccagcctggagcct
gcagcgcccctggagagcacagaggagggtgctgacacggagaggctgtcggggcgtctg
gggcgctcggagagcctgcgggtgagtgaccgccgccggccttcccggggcagcctcggg
gctaagggccggggtgggggccgctcccggagcgacgtggacatggaccccagctccgcc
acggccgtgcttggccctgcccgacgagccacccccgagcctggagacgagggggagccg
ggccgatcgggactagagctggaaccagaagagccccccggttggcgggagctcgtcccc
ccgggcaccctgcacagccttcccaagagccaggtgaagcggcaggaggtcatcagcgag
ctgctggtgacagaggcggcccacgtgcgcatgctccgggtgctctatgacctcttctac
cagcccatggcggatgggggcttcttctccctggaggagctacagaacatcttccccagc
ctggacgagctcatcgaggtgcattccctgttccttgatcgcctgatgaagcggaggcag
gacagtggctacctcattgaggagatcggagatgtgctgctggcccagtttgatggtacc
gagggctcctggttccagaaaatctcctcccgcttctgcagccgccagtcgtttgcctta
gagcagctcaaagccaaacagcgcaaggagcctcggttctgtgccttcgtgcaggaggcc
gagagccgcccccggtgccgccgcctgcagctgaaggacatgatccccacggagatgcag
cgtctgaccaagtacccgctgcttctgcagagcatcgggcagaacacagaagagcctgcg
gaacgggagaaagtggagctggccgctgagtgctgcagggaaattctgcaccacgtcaac
caagccgtgcgcgacatggaggacctgctgcggctcaaggattatcagaggcgcctggat
ttgtcccacctgcggcagagcagcgaccccatgctgagcgagttcaagaacctggatatc
accaagaagaagctggtccatgagggcccgctgacgtggcgggtgactaaggacaaggct
gtggaggtccacgtcctgctgctggacgacctgctgctgctgctgcagcgccaggatgag
cggctgctgctcaaatcgcacagccggacgctgacgcccacgcccgacggcaagaccatg
ctgcggccggtgctgcggctcacctccgccatgacccgagaggtggccaccgatcacaaa
gccttctatgtcatttttacctgggaccaggaggcccagatatacgagctggtggcccag
accgtgtcggagcggaagaactggtgtgccctcatcactgagaccgctggatccctgaag
gtccctgcccgcacctcccgacccaaacaccggcccagccccagcagcacccgtgaaccc
ctgctcagcagctctgagaacggcaacggtggccgagagatgcctccggctgacggccgg
atggagagaatcttcagcgccctcctgcccttctgcagaccaggccctgagggccagctc
gccgccaaggcccttcagaaagtgctgtccctgaagcagctcctgcttccctcggaggaa
gacagcggggtggggcctccgctcgaaggcgatggagtcccagggggcggccccccaagc
ccagtacagccccaggaaattcgggaggagctgctcagcctggaggagaccattaaacag
ctggaggaggtggaggaggagttttgccgcctgagactcctcctgtctccgctcggggag
aacactgtcccccagtctggctgtacctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (6)   
   Pfam (6)   
All databases (49)   

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